Technologies

Moderna booster shot and omicron: CDC guidance, effectiveness, side effects and more

Scientists and health officials strongly urge booster shots for Moderna and Pfizer as the omicron variant of the virus that causes COVID-19 begins to circulate in the US.

For the most up-to-date news and information about the coronavirus pandemic, visit the WHO and CDC websites.

Nearly 7 million booster shots — from Moderna, Pfizer and Johnson & Jonhson — were given last week in the US, a record high so far. The reason? In part, according to White House Coronavirus Response Coordinator Jeff Zients, is that people want to protect themselves against the omicron variant. «The best thing you can do if you’re concerned about omicron is to get boosted,» he said during a White House briefing on Tuesday.

Much is still unknown about the omicron variant, including how easily it can pass between people, how serious an infection it can cause and if it can evade immunity. But with more than 100 million people in the US eligible to receive a Moderna, Pfizer or Johnson & Johnson COVID-19 booster shot, the US is doubling down on COVID vaccine efforts, including administering booster shots. (President Joe Biden’s campaign also includes «free» at-home COVID-19 test kits and stricter travel rules for international travelers.)

Health professionals believe that booster shots from Moderna and Pfizercould help slow COVID’s spread, reducing hospitalization and deaths, asthe effects of the vaccine weaken over time. The CDC urges booster shots for anyone over 18, six months after theirsecond dose of Moderna or Pfizer, or two months after getting asingle Johnson & Johnson dose.

The COVID-19 vaccines have proven to be highly effective in preventing hospitalization. People who are unvaccinated are 10 times more likely to be hospitalized if infected. With the federal vaccine mandate halted by a court order, Biden is turning to other measures to get booster shots administered. The government has also ordered 13 million courses of antiviral drugs in anticipation of higher case loads this winter.

Here’s what you need to know about the Moderna booster, including doses, side effects and how to get a free ride. For more details, here’s the latest on COVID-19 vaccines for kids, how you can get a free COVID-19 test kit soon and what to know about breakthrough infections.

Does a COVID vaccine booster protect against the omicron variant?

While it could be two or three weeks until we know more about how easilyomicron can pass from person to person, and how resistant the COVID variant is against the current crop of vaccines, early data suggests the first series of shots and boosters may help guard against serious illness.In a White House briefing on Tuesday, Dr. Rochelle Walensky, director of the Centers for Disease Control and Prevention, said vaccines work and she anticipates they «willat least in part provide some protection against omicron.»

In the same briefing, Dr. Anthony Fauci said scientists are right now examining whether vaccine-induced antibodies lose some of their effectiveness with the omicron variant. Fauci, who is the chief medical advisor to the president, said they could know more as soon as the end of next week.

When is it time to get a COVID booster shot?

If you got Moderna or Pfizer, six months after the date of your second shot listed on yourvaccination card is when you’re eligible to receive your booster dose.The CDC and other health authorities are now urging you to get yourbooster as soon as you’re eligible, to keep your immune response againstomicron, delta and other coronavirus variants as strong as possible.Two months after the Johnson & Johnson vaccine is the time for abooster (more below).

On Dec. 2, Biden also outlined a plan forMedicare to contact the 64 million people it serves and for AARP toreach out to its 38 million senior members. Pharmacies like Walgreens,CVS, RiteAid and others will also contact people who got a vaccine attheir retail stores when it’s time to schedule another dose.

Should people who are pregnant get a booster shot?

The COVID booster recommendations apply to all people 18 years and older, including people who are pregnant. In fact, the CDC urges pregnant people to get a COVID vaccine — and a booster is half a full vaccine dose.

«People who are pregnant or recently pregnant are more likely to get severely ill with COVID-19 compared with people who are not pregnant,» the CDC says on its website.

A recent study also linked COVID-19 infection in pregnant people to higher risk of stillbirth. However, there is no evidence that getting vaccinated decreases fertility in women or men.

Is the Moderna booster shot a third dose?

Booster shots of COVID-19 vaccines are currently half doses of the same vaccine used in the first two full shots. The goal is to top up the vaccine formula that reinforces the body’s immune response against the virus and its variants. The Moderna booster authorized by the CDC is a 50-microgram dose, while the first two shots were each 100 micrograms.

Moderna is also working on a combination shot that contains this year’s flu vaccine and its COVID-19 booster vaccine, but that’s not available right now.

Is Moderna making an omicron booster shot?

Scientists worry the omicron variant could spread more quickly than the now-dominant delta variant because of the number of mutations the new strain has compared with delta. Moderna is currently working on an omicron-specific booster vaccine, along with testing a COVID-19 vaccine that could protect against several mutated strains of the coronavirus.

Like every other vaccine-maker around the world, Moderna is testing the effectiveness of its COVID-19 vaccine against omicron, but it may be weeks before lab tests show concrete evidence of how well Moderna protects people from the new variant.

As part of its booster testing, Moderna is also investigating whether a 100-microgram dose of its booster provides better protection against the omicron variant — in other words, a third dose rather than a half dose as the booster is currently formulated now.

If Moderna needs to make a new vaccine modified for the variant, it could be available early in2022.

How do I know which pharmacies have Moderna appointments?

Boosters are available at roughly 80,000 places across the country, including over 40,000 local pharmacies. Some 90% of Americans have a vaccine site within 5 miles of where they live.

A terrific free service in conjunction with the CDC sends you information when you text your ZIP code to this number: 438829. The response will show you COVID-19 vaccine locations in your area, along with the brand they carry for certain age groups, for instance, Moderna 18+. This can save you the trial and error of calling around, or showing up to your appointment to find that your booster of choice isn’t available. The text can also give you a shortcut to make your appointment right from your phone screen.

You can also check Vaccines.gov to see which vaccines are available where, and call 800-232-0233 for vaccine information.

How can I get a free ride to get my booster shot?

Lyft and Uber are offering free rides for some people who need them. An easy way to access those links for more information is through the text feature above You can also go to Lyft.com/vax or call Uber at: 855-921-0033.

Who can get a Moderna booster shot right now?

As of Nov. 19, all US adults — those age 18 and older — are eligible to get a booster shot of the COVID-19 vaccine. They qualify if it’s been at least six months since they’ve received a second dose of either the Moderna or Pfizer vaccine. Those who received the Johnson & Johnson vaccine are eligible for a booster dose after two months. Adults are encouraged to get whatever booster dose is available to them, even if that means mixing and matching vaccine boosters (more below), in other words, getting a different booster shot than their original vaccination.

What are the side effects of Moderna’s booster?

According to the CDC, those who got the Moderna booster dose reported fewer reactions than they did after the second dose of the vaccine. In its study, the CDC found 95% of those who got Moderna for the first round of vaccine shots chose Moderna for the booster dose.

Is it safe to mix and match vaccine and booster brands? Yes

The US Food and Drug Administration has authorized mixing COVID-19 boosters, which in the US means Moderna, Pfizer and Johnson & Johnson. Anyone eligible for a booster can get any of the available brands of coronavirus vaccines. If you initially received Johnson & Johnson and it’s been two months or longer since you received the initial dose, you’ll be able to get the Moderna or Pfizer booster. If you received Moderna or Pfizer for your first two shots, you could pick any authorized vaccine available to you — including J&J — if you qualify and it’s been six months or longer since your second shot.

Is the Moderna COVID-19 booster shot still free?

All booster shots will be free, regardless of immigration or health insurance status. However, depending on where you get your booster shot — for example, at a local pharmacy — you may be asked to log your insurance status. You may be asked to provide your insurance card information, including your name, date of birth and membership number. You will not be charged for your COVID-19 vaccine or booster shot.

Will I need another COVID booster shot?

The CDC updated its guidance to say that in 2022, some immunocompromised people will be able to get a fourth COVID-19 booster shot. It’s unclear if other groups will need to get a fourth dose at this time, but guidance could change in light of the omicron variant.

For more on coronavirus treatments and vaccines, here’s what we know about monoclonal antibody treatments, the new federal vaccine mandates and why some people may not want the shot.

What does the Moderna booster shot do?

A COVID-19 booster shot — whether from Moderna, Pfizer or Johnson & Johnson — tops off your immune response and guards against a breakthrough COVID-19 infection as the vaccine’s effectiveness decreases over time.

Recent studies of the Pfizer and AstraZeneca vaccines show that their effectiveness can begin to wane after six months. Moderna said early data suggests that those who received the Moderna vaccine in 2020 are showing a higher rate of breakthrough COVID-19 infections than those vaccinated this year, suggesting the need for a booster to maintain high levels of protection.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

Technologies

Elon Musk Says Starlink Could Replace Your Cellphone Carrier

Technologies

WWE 2K25 Jumps From the Top Rope Onto PlayStation Plus in September

Subscribers will also be able to play a turn-based strategy Persona game.

«The American Nightmare» Cody Rhodes, son of one of the greatest pro wrestlers of all time, «The American Dream» Dusty Rhodes, is the current undisputed WWE champion. And PlayStation Plus subscribers can bring Rhodes down a peg or help establish a new wrestling dynasty with the champion beginning on Sept. 16 in WWE 2K25.

PlayStation Plus is Sony’s version of Xbox Game Pass, and it offers subscribers a large and constantly expanding library of games. There are three PlayStation Plus tiers — Essential ($10 a month), Extra ($15 a month) and Premium ($18 a month) — and each gives subscribers access to games. However, only Extra and Premium tier subscribers can access the PlayStation Plus Game Catalog.

Here are all the games PS Plus Extra and Premium subscribers can access starting on Sept. 16. You can also check out the games all PS Plus subscribers can play in September, including Psychonauts 2.

Don’t miss any of our unbiased tech content and lab-based reviews. Add CNET as a preferred Google source.

WWE 2K25

Take control of your favorite superstar from the men’s and women’s divisions in this knockdown, dragout wrestling game. Become one of over 300 wrestlers from today and years past, like Rhea Ripley and Andre the Giant. This entry in the series also introduces intergender wrestling matches, barricade diving and new brawl environments where you can get over or turn heel.

Persona 5 Tactica

Join the Phantom Thieves in this real-time strategy game set in the Persona universe. You and the group wander into a bizarre realm where people are living under tyrannical oppression, and you cross paths with a revolutionary named Erina. Now you’re in cahoots with the rebels as you try to free an oppressed people and find your way back home.

Other games on PS Plus

Those are a few of the games Sony is bringing to PlayStation Plus, and subscribers can play these games as well starting on Sept. 16.

*Premium subscribers only.

For more on PlayStation Plus, here’s what to know about the service and a rundown of PS Plus Extra and Premium games added in August. You can also check out the latest and upcoming games on Xbox Game Pass and Apple Arcade.

Technologies

Little Nightmares 3 Hands-On: a Creepy Co-Op Game Arriving Just in Time for Halloween

The sequel adds cooperative play with all the haunting hallmarks of the earlier games.

After about an hour playing Little Nightmares 3, I’d used a person’s bisected halves to solve a puzzle, gotten a high score in a carnival shooting game and escaped the murderous claws of a deranged baby. As a 2-foot-tall youth trying to survive the morbid dangers of one demented area after another with my co-player, I was terrified and delighted.

I’ve only sampled the first two Little Nightmares games, but in my brief preview of Little Nightmares 3, it felt like a refined version of the series’ premise: small protagonists endangered by a large, grim world filled with traps to evade, puzzles to solve and horrid, lethal enemies to outwit. Take the scale of the animated horror movie 9, mix it with the darkest of stop-motion director Henry Selick’s maudlin settings and let players enjoy the haunting ride, room by perilous room.

This time, players aren’t alone. In Little Nightmares 3, developed by Supermassive Games, two players (or one and an AI companion) choose between characters Low (a bird-masked boy with a bow) and Alone (a girl with a jumpsuit and a wrench), who rely on each other and get out of rooms using their unique tools or just good ol’ fashioned teamwork. Sometimes this means pushing a box for the other to jump on, but other obstacles require rather complex puzzle-solving.

In the game, Low and Alone seek to escape the bleak Nowhere and its roulette of dystopian lands. My preview was limited to one of these areas — Carnevale, a demented circus where our small characters had to sneak under the feet of grotesque, ambling workers (or their corpses, tied up or swinging for the sport of their fellows). When we thought we were safe, possessed puppets sprinted after us until we could team up to knock their wooden heads off and crush them. Being noticed by anyone meant our demise, requiring frantic cooperation amid the anxious stakes of rather gruesome deaths.

It’s this tension and the dour setting that sets Little Nightmares 3 apart from other co-op games like the more excitable and dynamic Split Fiction released earlier this year, a rollercoaster flipbook of game genres that made for a breathless if not terribly coherent experience. In contrast, the section of Little Nightmares 3 I played unfolded like a series of grim vignettes that rely on its pleasingly goth trappings as much as working together with your friend (or computer teammate) to progress.

Surviving your little nightmares

While I got only an hour with the game, Little Nightmares 3 seems to iterate on rather than innovate away from its predecessors: Expect more of the same in new, grotesque settings, just with the welcome addition of tightly designed teamwork dynamics. For fans of the series, this is likely a good thing. There’s not much else like Little Nightmares.

The Carnevale stage I played through opened up with rain pelting red-and-white circus tent tops, which I as the masked Low (and someone from Bandai Namco who kindly played as the jumpsuit-wearing Alone) skittered between. Lumbering above us were brutish factory workers seeking escape at the funfair, which very quickly turned sinister as we very shortly saw some hanging tied-up as others took turns beating them like a piñata. We entered one room to find one worker in connected boxes as the subject of a magician’s saw-in-half trick…which was no trick, as we had to separate the halves to climb out of a window. I tried, and failed, to ignore the viscera slopping out of the boxes.

While we hid from the human-size enemies, we had to fight the wooden puppets. Like Geppeto’s most horrid creations, they ambushed us in several rooms, requiring me to knock their heads off with Low’s bow and run away from their decapitated bodies while my teammate rushed forward to crush their heads with Alone’s wrench.

But most of the rooms are about solving puzzles, which could be as simple as moving a box for my teammate to jump up and pull a switch or figure out how a radio plays into a complex solution. While these quiet moments are a nice break from the tense combat or pursuit, they also give time to appreciate the macabre backgrounds: I ran past one room with a circle of empty tall chairs only to come back a few seconds later to find them filled with puppets, unmoving but watching.

And then there are the really, really tense moments. We moved from the carnival to the adjoining candy factory (apparently where all those brutes work) and up to the offices where the boss works, to find him asleep with the TV droning on in the darkness…and his frankly hideous baby nestled next to him. Naturally, we had to make noise, cranking open a grate, awakening the terrifying spawn who ran after us. After many, many failed escapes, my teammate and I discovered we had to scramble for a hiding place after making it past the grate.

This was perhaps the most frustrating part of the preview as we panicked looking for a solution to our deadly woes (as opposed to the slow, methodical gameplay earlier) — but that’s part of the tension, especially when adding a teammate to the mix. Ultimately, it was a hard-won lesson in patience. In the next room, a kitchen, the nightmarish baby banged a bowl on the table until the father walked over to a corpse (presumably his worker) and cut out some meat for his ghoulish child to eat.

In my short time with it, Little Nightmares 3 seems like a cooperative spooky storybook for players and their friends (but not couch buddies, sadly — it’s online co-op only) to experience. How much it lives up to previous games in the series, especially as developer Supermassive Games takes more of the reins from the franchise’s original creators Tarsier Games, is anyone’s guess. (Tarsier’s similar spiritual sequel to Little Nightmares, Reanimal, is coming in 2026.)

But as the air turns crisp and Halloween beckons, it’s the best time of the year for a creepy co-op game like Little Nightmares 3 to land.

Little Nightmares 3 comes out Oct.10, 2025, for PC, PS4, PS5, Xbox One, Xbox Series X/S, Nintendo Switch and Nintendo Switch 2.