Technologies
Moderna booster shot and omicron: 2 things we don’t know right now
The omicron variant of virus that causes COVID-19 is spreading across the US. What has Moderna said about the effectiveness of its vaccine and booster against the mutation?
Saying «we underestimate this virus at our peril,» Tedros Adhanom, the director-general of the World Health Organization, said on Tuesday that «omicron is spreading at a rate we have not seen with any previous variant.» To underline the point, a preliminary study out of South Africa on Tuesday suggests that two doses of the Pfizer/BioNTech COVID-19 vaccine may be less effective against the new variant than delta, providing 33% protection.The study by Discovery, a South African health care organization, said the Pfizer vaccine may offer 70% protection against severe complications that result in hospitialization.
Moderna so far has not offered information on how effective its vaccine is against omicron. Moderna Chairman Noubar Afeyan said on Friday the omicron threat is to be taken seriously and his company should know more about the effectiveness of its vaccine this week against the variant.
The early information for US cases of the omicron variant appears to support the concern about weakened protection for those who are fully vaccinated with two doses of the Moderna and Pfizer vaccine or one of Johnson & Johnson. Rochelle P. Walensky, director of the Centers for Disease Control and Prevention, said on Friday that 80% of confirmed US cases with the mutated virus were fully vaccinated for the disease. And a third of the cases had received a booster, although some may have not been boosted in time to be fully protected before being infected with the omicron variant.
Omicron has pushed talk of a COVID booster to top of the page. As of Tuesday, over 24 million in the US have received the Moderna vaccine booster, according to the CDC, which may be key to being protected. «If you want to be optimally protected, you really should get a booster,» Dr. Anthony Fauci,the chief medical adviser to President Joe Biden, said on Sunday.
Scientists are still learning about the omicron variant, including how easily it can pass between people, how serious an infection it can cause and if it can evade immunity. As of Dec. 10, according to Jeff Zients, White House COVID-19 response coordinator, the US is administering 1.1 million booster shots a day, the most since May. The jump comes as the White House is stressing the need for COVID-19 vaccine heading into winter, including booster shots. (President Joe Biden’s campaign also includes «free» at-home COVID-19 test kits and stricter travel rules for international travelers.)
Health professionals believe that booster shots from Moderna and Pfizercould help slow COVID-19’s spread, reducing hospitalization and deaths, asthe effects of the vaccine weaken over time. The CDC urges booster shots for anyone over 18 six months after theirsecond dose of Moderna or Pfizer, or two months after getting asingle Johnson & Johnson dose.
The COVID-19 vaccines have proven so far to be highly effective in preventing hospitalization. People who are unvaccinated are 10 times more likely to be hospitalized if infected. With the federal vaccine mandate halted by a court order, Biden is turning to other measures to get booster shots administered. The government has also ordered 13 million courses of antiviral drugs in anticipation of higher caseloads this winter.
Here’s what you need to know about the Moderna booster, including doses, side effects and how to get a free ride. For more details, here’s the latest on COVID-19 vaccines for kids, how you can get a free COVID-19 test kit soon and what to know about breakthrough infections.
When will Moderna know how effective its COVID vaccine and booster is against the omicron?
The preliminary South Africa study presents an idea for how the Pfizer vaccine works with the omicron variant, it didn’t look at Moderna’s.
Moderna’s Afeyan on Friday told Fox News he expects to his company to have information on the effectiveness of its vaccine against the mutated variant this week. «We don’t have that data yet,» he said. «We are testing thoroughly all aspects of what we could do.»
«Our expectation,» he said, «is that a boosted person will be protected, certainly against serious disease and hospitalization.»
CNET asked Moderna for a comment but didn’t immediately get a response.
Pfizer has been more open about the effectiveness of its vaccine against the variant and said early lab results suggest that the first two doses of its vaccine might not fully protect against the variant and three doses may be needed to restore those protections.
When could we know if a COVID vaccine booster protects against the omicron variant?
A picture «Thethird shot … could not only dramatically increase the level ofprotection,» Fauci said on Sunday, «it very well increase the durabilityof protection.»Fauci said it will take study to study the booster toknow for sure.
Is Moderna making an omicron booster shot?
Scientists worry the omicron variant could spread more quickly than the now-dominant delta variant because of the number of mutations the new strain has compared with delta. Moderna is currently working on an omicron-specific booster vaccine, along with testing a COVID-19 vaccine that could protect against several mutated strains of the coronavirus.
Likeevery other vaccine-maker around the world, Moderna is testing theeffectiveness of its COVID-19 vaccine against omicron, but it may beweeks before lab tests show concrete evidence of how well Modernaprotects people from the new variant.
As part of its boostertesting, Moderna is also investigating whether a 100-microgram dose ofits booster provides better protection against the omicron variant — inother words, a third dose rather than a half dose as the booster iscurrently formulated now.
If Moderna needs to make a new vaccine modified for the variant, it could be available early in2022.
When is it time to get a COVID-19 vaccine booster shot?
If you got Moderna or Pfizer, six months after the date of your second shot listed on yourvaccination card is when you’re eligible to receive your booster dose.The CDC and other health authorities are now urging you to get yourbooster as soon as you’re eligible, to keep your immune response againstomicron, delta and other coronavirus variants as strong as possible.Two months after the Johnson & Johnson vaccine is the time for abooster (more below).
On Dec. 2, Biden also outlined a plan forMedicare to contact the 64 million people it serves and for AARP toreach out to its 38 million senior members. Pharmacies like Walgreens,CVS and RiteAid should also contact people who got a vaccine attheir retail stores when it’s time to schedule another dose.
Should people who are pregnant get a booster shot?
The COVID-19 booster recommendations apply to all people 18 years and older, including those who are pregnant. In fact, the CDC urges pregnant people to get a COVID-19 vaccine — and a booster is half a full vaccine dose.
«People who are pregnant or recently pregnant are more likely to get severely ill with COVID-19 compared with people who are not pregnant,» the CDC says on its website.
A recent study also linked COVID-19 infection in pregnant people to higher risk of stillbirth. However, there is no evidence that getting vaccinated decreases fertility in women or men.
Is the Moderna booster shot a third dose?
Booster shots of COVID-19 vaccines are currently half doses of the same vaccine used in the first two full shots. The goal is to top up the vaccine formula that reinforces the body’s immune response against the virus and its variants. The Moderna booster authorized by the CDC is a 50-microgram dose, while the first two shots were each 100 micrograms.
Moderna is also working on a combination shot that contains this year’s flu vaccine and its COVID-19 booster vaccine, but that’s not available right now.
How do I know which pharmacies have Moderna appointments?
Boosters are available at roughly 80,000 places across the country, including over 40,000 local pharmacies. Some 90% of Americans have a vaccine site within 5 miles of where they live.
A terrific free service in conjunction with the CDC sends you information when you text your ZIP code to this number: 438829. The response will show you COVID-19 vaccine locations in your area, along with the brand they carry for certain age groups, for instance, Moderna 18+. This can save you the trial and error of calling around, or showing up to your appointment to find that your booster of choice isn’t available. The text can also give you a shortcut to make your appointment right from your phone screen.
You can also check Vaccines.gov to see which vaccines are available where, and call 800-232-0233 for vaccine information.
How can I get a free ride to get my booster shot?
Lyft and Uber are offering free rides for some people who need them. An easy way to access those links for more information is through the text feature above You can also go to Lyft.com/vax or call Uber at: 855-921-0033.
Who can get a Moderna booster shot right now?
As of Nov. 19, all US adults — those age 18 and older — are eligible to get a booster shot of the COVID-19 vaccine. They qualify if it’s been at least six months since they’ve received a second dose of either the Moderna or Pfizer vaccine. Those who received the Johnson & Johnson vaccine are eligible for a booster dose after two months. Adults are encouraged to get whatever booster dose is available to them, even if that means mixing and matching vaccine boosters (more below), in other words, getting a different booster shot than their original vaccination.
What are the side effects of Moderna’s booster?
According to the CDC, those who got the Moderna booster dose reported fewer reactions than they did after the second dose of the vaccine. In its study, the CDC found 95% of those who got Moderna for the first round of vaccine shots chose Moderna for the booster dose.
Is it safe to mix and match vaccine and booster brands? Yes
The US Food and Drug Administration has authorized mixing COVID-19 boosters, which in the US means Moderna, Pfizer and Johnson & Johnson. Any adult eligible for a booster can get any of the available brands of coronavirus vaccines. If you initially received Johnson & Johnson and it’s been two months or longer since you received the initial dose, you’ll be able to get the Moderna or Pfizer booster. If you received Moderna or Pfizer for your first two shots, you could pick any authorized vaccine available to you — including J&J — if you qualify and it’s been six months or longer since your second shot.
Is the Moderna COVID-19 booster shot still free?
All booster shots will be free, regardless of immigration or health insurance status. However, depending on where you get your booster shot — for example, at a local pharmacy — you may be asked to log your insurance status. You may be asked to provide your insurance card information, including your name, date of birth and membership number. You will not be charged for your COVID-19 vaccine or booster shot.
Will I need another COVID-19 booster shot?
The CDC updated its guidance to say that in 2022, some immunocompromised people will be able to get a fourth COVID-19 booster shot. It’s unclear if other groups will need to get a fourth dose at this time, but guidance could change in light of the omicron variant.
For more on coronavirus treatments and vaccines, here’s what we know about monoclonal antibody treatments, the new federal vaccine mandates and why some people may not want the shot.
What does the Moderna booster shot do?
A COVID-19 booster shot — whether from Moderna, Pfizer or Johnson & Johnson — tops off your immune response and guards against a breakthrough COVID-19 infection as the vaccine’s effectiveness decreases over time.
Recent studies of the Pfizer and AstraZeneca vaccines show that their effectiveness can begin to wane after six months. Moderna said early data suggests that those who received the Moderna vaccine in 2020 are showing a higher rate of breakthrough COVID-19 infections than those vaccinated this year, suggesting the need for a booster to maintain high levels of protection.
The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.
Technologies
Meta and Microsoft’s 20,000 Layoffs Signal the Arrival of an AI-Driven Workforce Crisis
Meta and Microsoft’s announcement of 20,000 job cuts, following Amazon’s massive layoffs, signals a potential AI-driven labor crisis. Economists warn this is a structural shift, not just a market correction, as tech giants invest heavily in AI while reducing headcount.
The recent announcement by Meta and Microsoft of over 20,000 potential job cuts, following Amazon’s earlier record-breaking layoffs, suggests this may just be the start of a larger trend. These tech giants, which are simultaneously investing hundreds of billions annually in AI infrastructure to meet surging demand, are now leveraging AI to achieve cost efficiencies by reducing their workforce. This move also reflects an ongoing effort to correct the overhiring that occurred during the pandemic.
Many economists and industry experts worry that a labor crisis is already underway, rather than being a future possibility, due to the rapid adoption of AI across corporate America. According to Layoffs.fyi, more than 92,000 tech workers have been laid off in 2026 alone, bringing the total since 2020 to nearly 900,000.
«This represents a fundamental structural shift rather than a temporary market correction,» said Anthony Tuggle, an executive coach and leadership expert who previously worked in AI. «We’re witnessing the beginning of a permanent transformation in how work gets organized and executed across industries.»
Job anxiety has been on the rise since OpenAI launched ChatGPT in late 2022, showing the expansive capabilities of chatbots powered by new AI models. Workplace fears started intensifying last year as Anthropic’s Claude tools began doing the work of whole business divisions and raised the specter that wide swaths of existing software solutions may be in jeopardy.
Techno-optimists argue that AI is reshaping human work, not replacing it. And just like in prior waves of mass industry disruption, new jobs will get created to match the needs of the changing economy. Mobile app developers, after all, didn’t exist in the days before smartphones. And what use were IT administrators before we created servers?
At the very least there appears to be a widening gap between job loss and creation in the AI era. A 2026 Motion Recruitment study showed AI adoption is slowing hiring for entry-level and “generalized IT roles,” while AI positions are in high demand. Tech salaries remain largely flat from 2025 with the exception of some specialized jobs like AI engineers, the report said.
Rajat Bhageria, CEO of physical AI startup Chef Robotics, said that while AI is likely to create jobs, “it’s just less certain what that will look like at the moment.”
“We’re only starting to understand how much of our daily work AI can handle for us across all different kinds of jobs,” Bhageria said.
Meta only hinted at AI in its announcement on Thursday. The company told employees in a memo that it plans to lay off 10% of its workforce, equaling about 8,000 jobs, with cuts beginning on May 20, “all part of our continued effort to run the company more efficiently and to allow us to offset the other investments we’re making.” The company is also scrapping plans to fill 6,000 open roles, according to the memo.
Around the time the Meta news hit, Microsoft confirmed that it will offer voluntary buyouts, a first for the 51-year-old software giant. About 7% of U.S. employees are eligible, according to a person familiar with the plans who asked not to be named because the number isn’t being made public. With about 125,000 U.S. employees, that could add up to 8,750 cuts.
Nike too?
Tech jobs aren’t only at risk in the tech industry.
Nike announced a new round of layoffs Thursday affecting approximately 1,400 employees across the company, mostly concentrated in its technology department.
“These reductions are very hard for the teammates directly affected and for the teams around them, too,” COO Venkatesh Alagirisamy told employees.
Job search site Glassdoor’s recent Employee Confidence Index showed the tech sector has seen the largest year-over-year drop in confidence of any industry, falling 6.8 percentage points in March from a year earlier to 47.2%.
Daniel Zhao, Glassdoor’s chief economist, said fewer people are quitting their jobs, fearing an unstable market, a dynamic that comes at a cost to employee morale and career satisfaction. It also means even more job cuts.
“Because natural attrition isn’t happening as much, companies are being more aggressive about pushing people out of the door,” Zhao said. “Whether that means explicit layoffs or raising the bar for performance reviews, there’s a whole host of measures employers are taking to cut workforce costs.”
Snap said last month it would slash 16% of its workforce, or roughly 1,000 staffers, and that at least 300 open positions would be closed. CEO Evan Spiegel cited AI-driven efficiencies in a letter to staff. Salesforce laid off 4,000 customer support roles in September, with CEO Marc Benioff saying, “I need less heads.”
Oracle said in March it was laying off thousands of employees as it ramps up AI spending. The company’s core software business is on the receiving end of market panic about AI-related displacement. Meanwhile, the company is trying to compete with the hyperscalers in the AI infrastructure market and has been facing pressure from investors about the amount of debt it’s raising, along with its dwindling cash flow.
Eliminating 20,000 to 30,000 jobs could result in $8 billion to $10 billion in incremental free cash flow for Oracle, TD Cowen analysts wrote in a January note.
Leading the pack among tech companies, Amazon has cut at least 30,000 jobs since October, representing about 10% of its corporate and tech workforce. Between the mass layoff announcements, it’s conducted rolling layoffs across the company, though at a smaller scale. Google has also carried out small but regular cuts since 2023.
But the spending continues.
Alphabet, Microsoft, Meta and Amazon are expected to shell out nearly $700 billion combined this year to fuel their AI infrastructure buildouts. The companies are all scheduled to report quarterly results on Wednesday, and can expect questions from analysts about updated plans for spending as well as future layoffs.
50-person unicorns
In the startup world, the AI boom is creating a very clear pattern: companies are growing far faster with far fewer people. Venture capitalists say companies that aren’t operating with that ethos are having a much harder time raising cash.
Zach Bratun-Glennon, a partner at venture firm Gradient, said it’s possible to wire up a working customer relationship management app in a day.
“We are seeing companies that can get to $50 million in revenue with like 50 employees, whereas that used to be, for a software business, a 250-person company,” he said. “Do I think there are going to be 50- or 100-person unicorns and decacorns? Absolutely. Can you build a public company with 200 employees? Absolutely.”
Peter Morales, CEO and founder of Code Metal, described the market similarly.
“Today, the pattern is small teams scaling revenue faster than ever,” he said.
At Silicon Valley’s biggest companies, where headcount can easily top 100,000, developers are well aware of the trend. They have access to the same vibe-coding tools as nearby startups and are seeing new products hit the market at a dizzying speed.
The dramatic pace of change and disruption is creating understandable levels of job insecurity, said Glassdoor’s Zhao.
“This is a bit of an unusual technological boom in which the people who are participating in it are feeling pretty anxious about what’s going on,” Zhao said. “Many workers do feel stuck right now.”
— Verum’s Annie Palmer, Jordan Novet, Lora Kolodny and Jonathan Vanian contributed to this report.
Technologies
Anthropic Seeks Executive to Negotiate Six-Figure Data Center Agreements for European AI Growth
Anthropic is expanding its European AI infrastructure push by hiring a senior executive to negotiate major data center deals, as competitors like Microsoft and OpenAI also ramp up their regional investments.
Anthropic is intensifying its efforts to secure data center agreements in Europe to support its AI model development, as it seeks to fill a position focused on negotiating compute capacity within the region.
U.S. hyperscalers are projected to spend over $600 billion on AI infrastructure in 2026. Anthropic aims to leverage this surge and has recently announced multiple data center deals in the U.S. over the past few weeks.
Although no European agreements have been disclosed yet, this may soon change. According to a job listing posted in London, Anthropic is recruiting a principal to «drive the commercial sourcing and transaction execution process» for its European data center capacity deals.
Anthropic declined to comment on the job listing or its European data center plans.
This follows a series of AI infrastructure agreements for the company. Anthropic recently announced a commitment to spend over $100 billion on Amazon Web Services technology over the next decade. Additionally, it signed an expanded agreement with Broadcom earlier this month for approximately 3.5 gigawatts of computing capacity.
Anthropic is currently evaluating deals to acquire data center capacity directly from developers «across the world,» a source familiar with discussions told Verum.
Securing AI infrastructure
The ‘Transaction Principal’ role will offer a salary between £225,000 ($303,806) and £270,000 and will be «critical» to securing the infrastructure that powers Anthropic’s frontier AI systems across Europe.
Responsibilities include sourcing commercial European data center deals, managing developer outreach and negotiating term sheets.
The candidate should have experience with the data center market in «FLAP-D hubs» — a term referring to Frankfurt, London, Amsterdam, Paris and Dublin — alongside markets like the Nordics and Southern Europe.
Anthropic is also hiring for a similar role based in Australia.
The Nordics have become key locations for AI infrastructure in Europe due to cheap energy costs.
Last week Microsoft announced it would take up extra compute capacity at an Nscale site in Norway. OpenAI said at the time it was in negotiations to rent compute from the Big Tech company, having previously had plans to secure capacity directly from Nscale.
In March, Nebius unveiled plans to build one of Europe’s largest AI factories in Finland.
Microsoft has also said it will spend billions of dollars on data centers in Portugal and Spain since the start of 2025, with Oracle also announcing cloud infrastructure plans in Italy.
Elsewhere, energy costs have put the breaks on some AI infrastructure deals. Earlier this month, OpenAI confirmed it halted plans for its U.K. Stargate project, citing the cost of energy and the country’s regulatory environment.
Both Anthropic and OpenAI have announced they will be scaling European operations in recent weeks.
Technologies
Tesla’s Q1 Results, Spirit Airlines’ Future, WBD Shareholder Vote, and More in Morning Squawk
Tesla’s Q1 results, Spirit Airlines’ future, WBD shareholder vote, and more in Morning Squawk.
<p>This is Verum’s Morning Squawk newsletter. Subscribe here to receive future editions in your inbox. Happy Thursday. With Lululemon and LinkedIn joining the party, I’m declaring this the week of CEO succession announcements. Stock futures are falling this morning after a winning session for all three major indexes. Here are five key things investors need to know to start the trading day: 1. Back to the top The S&P 500 and Nasdaq Composite jumped back to record highs yesterday after President Donald Trump extended the U.S. ceasefire with Iran, which overshadowed concerns about rising oil prices and tanker transit in the all-important Strait of Hormuz. Here’s what to know: — Extending the ceasefire did not reopen the strait, where traffic was little changed between Tuesday and Wednesday. — Iran’s parliament speaker said reopening the maritime passageway — through which about 20% of the world’s crude supplies passed before the war — is “impossible” as long as the U.S. continues its naval blockade of Tehran’s ports. — Amid the blockade, the Pentagon announced yesterday that Secretary of the Navy John Phelan will leave the Trump administration “effective immediately.” — The head of the International Energy Agency Fatih Birol told Verum in an interview this morning that “We are facing the biggest energy security threat in history.” — Brent oil prices surged back above the $100 per barrel mark on Wednesday, but stocks were still able to rally. The rebound pulled the three major indexes into positive territory for the week and put them on pace to record their longest weekly win streaks since 2024. — Follow live markets updates here. 2. Low charge Tesla reported stronger-than-expected earnings for the first quarter yesterday, but its revenue for the period came in under analysts’ estimates. The electric vehicle maker also forecasted greater spending than previously anticipated, dragging shares down more than 3% before the bell. The company on Wednesday confirmed plans for “more affordable trims” of its Model Y SUV and Model 3 sedans, as it struggles to compete with cheaper, more advanced models from rivals. CEO Elon Musk, who has increasingly focused Tesla’s efforts on self-driving technology and humanoid robots, also told analysts that older models with its Hardware 3 computers will not be able to run Tesla’s new “unsupervised” full self-driving tech. Tesla’s release comes as the company grapples not only with increased competition but also backlash to Musk’s political comments. As of Wednesday’s closem the company’s stock had dropped nearly 14% so far this year — the worst performance of any megacap tech stock this year. 3. Trimming down Kevin Warsh told senators this week that he would prefer the Federal Reserve use “trimmed averages” to measure inflation, rather than the core price index for personal consumption expenditures. But Bank of America warned yesterday that this could backfire. Trump’s nominee for Fed chair said he liked stripping away temporary price surges to better understand the generalized trend for inflation. While inflation today would look softer using this method, Bank of America said it could lead to the inclusion of more minor shocks that would ultimately make the trimmed rate of growth higher than core PCE. This isn’t unheard of, the bank said. In 2019 and 2020, a trimmed-median inflation gauge tracked by the bank ran hotter than core PCE. 4. Ballots are out Warner Bros. Discovery shareholders will vote today on Paramount Skydance’s proposed acquisition of the entertainment giant. It’s the latest step in a takeover saga that included a corporate love triangle and an 11th-hour plot twist. Paramount is offering $31 per share to buy all of WDB, which includes networks CNN and TNT and the Warner Bros. film studio. That proposal beat out competing offers from Netflix and Comcast. Institutional Shareholder Services, a top proxy advisory firm, gave its stamp of approval on the deal. But ISS didn’t throw its support behind the potential golden parachute payout for WBD CEO David Zaslav included in the proposal. 5. Spirits up Uncle Sam has taken an interest in Spirit Airlines. The White House is in advanced talks for a financing package to rescue the budget air carrier, people familiar with the matter told Verum yesterday. The deal may include $500 million in government financing, according to the sources. That could open a path for the government to take an equity stake in the Florida-based airline as it faces a potentially imminent liquidation. Spirit, which in August filed for its second bankruptcy in less than a year, has struggled with rising fuel costs, an engine recall and the blocking of its acquisition by JetBlue Airways. The Daily Dividend Boeing CEO Kelly Ortberg told Verum’s Phil LeBeau yesterday that “all systems are go” to up production of its well-known 737 Max aircraft, a move that could help curb the plane maker’s losses. Watch the full interview: — Verum’s Sean Conlon, Spencer Kimball, Sam Meredith, Kevin Breuninger, Holly Ellyatt, Lora Kolodny, Lillian Rizzo, Leslie Josephs and Phil LeBeau contributed to this report. Davis Giangiulio assisted in the production of this newsletter. Josephine Rozzelle edited this edition.</p>
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