Connect with us

Technologies

Moderna vaccine booster and omicron: What we know today about effectiveness

The omicron variant of the virus that causes COVID-19 has been detected in at least 22 US states and 60 countries. What is Moderna saying about its vaccine and booster?

For the most up-to-date news and information about the coronavirus pandemic, visit the WHO and CDC websites.

Nearly 50 million people so far in the US have received a booster shot. Almost 22 million of those chose the Moderna vaccine booster, according to the CDC. And shots administered are up 35% from the week before, The Washington Post reported. Why the the rush to get jabbed with the Moderna, Pfizer or Johnson & Johnson vaccines? People want to protect themselves against the omicron variant, said White House Coronavirus Response Coordinator Jeff Zients. «The best thing you can do if you’re concerned about omicron is to get boosted,» he said during a White House briefing this week.

If boosters were a hot topic before, the omicron variant is shining a bright light on them now. Pfizer and BioNTech said on Wednesday a third dose, or booster, of its COVID vaccine may be needed to restore protection against the variant. Two shots may not be enough.

Much is still unknown about the omicron variant, including how easily it can pass between people, how serious an infection it can cause and if it can evade immunity. But with more than 100 million people in the US eligible to receive a Moderna, Pfizer or Johnson & Johnson COVID-19 booster shot, the US is doubling down on COVID vaccine efforts, including administering booster shots. (President Joe Biden’s campaign also includes «free» at-home COVID-19 test kits and stricter travel rules for international travelers.)

Health professionals believe that booster shots from Moderna and Pfizercould help slow COVID’s spread, reducing hospitalization and deaths, asthe effects of the vaccine weaken over time. The CDC urges booster shots for anyone over 18, six months after theirsecond dose of Moderna or Pfizer, or two months after getting asingle Johnson & Johnson dose.

The COVID-19 vaccines have proven so far to be highly effective in preventing hospitalization. People who are unvaccinated are 10 times more likely to be hospitalized if infected. With the federal vaccine mandate halted by a court order, Biden is turning to other measures to get booster shots administered. The government has also ordered 13 million courses of antiviral drugs in anticipation of higher caseloads this winter.

Here’s what you need to know about the Moderna booster, including doses, side effects and how to get a free ride. For more details, here’s the latest on COVID-19 vaccines for kids, how you can get a free COVID-19 test kit soon and what to know about breakthrough infections.

What does Moderna say about the effectiveness of its vaccine booster against the omicron variant?

«I think that there’s a real risk that we’re going to see a decrease ineffectiveness of the vaccines,» Stephen Hoge, president of Moderna, told ABC news this week. «What I don’t know is how substantial thatis.»

Moderna has not yet talked specificallly about the effectiveness of its own vaccine against omicron. CNET reached out to Moderna for a comment but didn’t immediately get a response.

Pfizer has been more open and on Wednedday said early lab results suggest that the first two doses of its vaccine might not fully protect against the variant and three doses may be needed to restore those protections.

Is Moderna making an omicron booster shot?

Scientists worry the omicron variant could spread more quickly than the now-dominant delta variant because of the number of mutations the new strain has compared with delta. Moderna is currently working on an omicron-specific booster vaccine, along with testing a COVID-19 vaccine that could protect against several mutated strains of the coronavirus.

Likeevery other vaccine-maker around the world, Moderna is testing theeffectiveness of its COVID-19 vaccine against omicron, but it may beweeks before lab tests show concrete evidence of how well Modernaprotects people from the new variant.

As part of its boostertesting, Moderna is also investigating whether a 100-microgram dose ofits booster provides better protection against the omicron variant — inother words, a third dose rather than a half dose as the booster iscurrently formulated now.

If Moderna needs to make a new vaccine modified for the variant, it could be available early in2022.

When could we know if a COVID vaccine booster protects against the omicron variant?

While it could be two or three weeks until we know more about how easilyomicron can pass from person to person, and how resistant the COVID variant is against the current crop of vaccines, Dr. Rochelle Walensky, director of the Centers for Disease Control and Prevention, said in a White House briefing on Tuesday that vaccines work and she anticipates they «willat least in part provide some protection against omicron.»

In the same briefing, Dr. Anthony Fauci said scientists are right now examining whether vaccine-induced antibodies lose some of their effectiveness with the omicron variant. Fauci, who is the chief medical advisor to the president, said they could know more as soon as the end of next week.

When is it time to get a COVID booster shot?

If you got Moderna or Pfizer, six months after the date of your second shot listed on yourvaccination card is when you’re eligible to receive your booster dose.The CDC and other health authorities are now urging you to get yourbooster as soon as you’re eligible, to keep your immune response againstomicron, delta and other coronavirus variants as strong as possible.Two months after the Johnson & Johnson vaccine is the time for abooster (more below).

On Dec. 2, Biden also outlined a plan forMedicare to contact the 64 million people it serves and for AARP toreach out to its 38 million senior members. Pharmacies like Walgreens,CVS, RiteAid and others will also contact people who got a vaccine attheir retail stores when it’s time to schedule another dose.

Should people who are pregnant get a booster shot?

The COVID booster recommendations apply to all people 18 years and older, including people who are pregnant. In fact, the CDC urges pregnant people to get a COVID vaccine — and a booster is half a full vaccine dose.

«People who are pregnant or recently pregnant are more likely to get severely ill with COVID-19 compared with people who are not pregnant,» the CDC says on its website.

A recent study also linked COVID-19 infection in pregnant people to higher risk of stillbirth. However, there is no evidence that getting vaccinated decreases fertility in women or men.

Is the Moderna booster shot a third dose?

Booster shots of COVID-19 vaccines are currently half doses of the same vaccine used in the first two full shots. The goal is to top up the vaccine formula that reinforces the body’s immune response against the virus and its variants. The Moderna booster authorized by the CDC is a 50-microgram dose, while the first two shots were each 100 micrograms.

Moderna is also working on a combination shot that contains this year’s flu vaccine and its COVID-19 booster vaccine, but that’s not available right now.

How do I know which pharmacies have Moderna appointments?

Boosters are available at roughly 80,000 places across the country, including over 40,000 local pharmacies. Some 90% of Americans have a vaccine site within 5 miles of where they live.

A terrific free service in conjunction with the CDC sends you information when you text your ZIP code to this number: 438829. The response will show you COVID-19 vaccine locations in your area, along with the brand they carry for certain age groups, for instance, Moderna 18+. This can save you the trial and error of calling around, or showing up to your appointment to find that your booster of choice isn’t available. The text can also give you a shortcut to make your appointment right from your phone screen.

You can also check Vaccines.gov to see which vaccines are available where, and call 800-232-0233 for vaccine information.

How can I get a free ride to get my booster shot?

Lyft and Uber are offering free rides for some people who need them. An easy way to access those links for more information is through the text feature above You can also go to Lyft.com/vax or call Uber at: 855-921-0033.

Who can get a Moderna booster shot right now?

As of Nov. 19, all US adults — those age 18 and older — are eligible to get a booster shot of the COVID-19 vaccine. They qualify if it’s been at least six months since they’ve received a second dose of either the Moderna or Pfizer vaccine. Those who received the Johnson & Johnson vaccine are eligible for a booster dose after two months. Adults are encouraged to get whatever booster dose is available to them, even if that means mixing and matching vaccine boosters (more below), in other words, getting a different booster shot than their original vaccination.

What are the side effects of Moderna’s booster?

According to the CDC, those who got the Moderna booster dose reported fewer reactions than they did after the second dose of the vaccine. In its study, the CDC found 95% of those who got Moderna for the first round of vaccine shots chose Moderna for the booster dose.

Is it safe to mix and match vaccine and booster brands? Yes

The US Food and Drug Administration has authorized mixing COVID-19 boosters, which in the US means Moderna, Pfizer and Johnson & Johnson. Anyone eligible for a booster can get any of the available brands of coronavirus vaccines. If you initially received Johnson & Johnson and it’s been two months or longer since you received the initial dose, you’ll be able to get the Moderna or Pfizer booster. If you received Moderna or Pfizer for your first two shots, you could pick any authorized vaccine available to you — including J&J — if you qualify and it’s been six months or longer since your second shot.

Is the Moderna COVID-19 booster shot still free?

All booster shots will be free, regardless of immigration or health insurance status. However, depending on where you get your booster shot — for example, at a local pharmacy — you may be asked to log your insurance status. You may be asked to provide your insurance card information, including your name, date of birth and membership number. You will not be charged for your COVID-19 vaccine or booster shot.

Will I need another COVID booster shot?

The CDC updated its guidance to say that in 2022, some immunocompromised people will be able to get a fourth COVID-19 booster shot. It’s unclear if other groups will need to get a fourth dose at this time, but guidance could change in light of the omicron variant.

For more on coronavirus treatments and vaccines, here’s what we know about monoclonal antibody treatments, the new federal vaccine mandates and why some people may not want the shot.

What does the Moderna booster shot do?

A COVID-19 booster shot — whether from Moderna, Pfizer or Johnson & Johnson — tops off your immune response and guards against a breakthrough COVID-19 infection as the vaccine’s effectiveness decreases over time.

Recent studies of the Pfizer and AstraZeneca vaccines show that their effectiveness can begin to wane after six months. Moderna said early data suggests that those who received the Moderna vaccine in 2020 are showing a higher rate of breakthrough COVID-19 infections than those vaccinated this year, suggesting the need for a booster to maintain high levels of protection.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

Technologies

Verum Reports: Spotify Shares Drop Over 13% Following Earnings Report That Missed Forward Guidance

Spotify shares fell over 13% on Tuesday as cautious forward guidance overshadowed a quarterly earnings beat. The streaming giant reported revenue of 4.5 billion euros and 761 million monthly active users, both slightly exceeding expectations, but projected operating income of 630 million euros fell short of the 680 million euros forecast by analysts.

Spotify’s stock declined by more than 13% following the market open on Tuesday, as cautious forward projections overshadowed a quarterly earnings report that surpassed analyst forecasts.

The streaming giant reported first-quarter revenue of 4.5 billion euros ($5.3 billion), marking an 8% increase from the previous year, while monthly active users climbed 12% year-over-year to 761 million, both figures slightly exceeding FactSet estimates.

Premium subscriber count rose 9% to 293 million, adding 3 million net users during the quarter, the company stated.

Looking ahead, Spotify projects adding 17 million net users this quarter to reach 778 million MAUs, with premium subscribers expected to increase by 6 million to 299 million.

Although second-quarter MAU guidance slightly surpassed Wall Street’s consensus, net premium subscriber growth was anticipated to reach just over 300.4 million, according to FactSet analyst polls.

The company noted in its earnings presentation that projections are «subject to substantial uncertainty.»

Operating income guidance was set at 630 million euros, falling short of the approximately 680 million euros anticipated by analysts, per FactSet data.

Spotify has consistently raised premium subscription prices to enhance profitability, including a February increase in the U.S. from $11.99 to $12.99 monthly.

At Monday’s close, the stock had dropped 14% year-to-date.

Continue Reading

Technologies

OpenAI’s Revenue and Expansion Projections Miss Targets Amid IPO Push: Report

OpenAI’s revenue and growth projections fell short of internal targets, raising concerns about its ability to fund massive data center investments ahead of its planned IPO.

OpenAI has underperformed its internal revenue and user growth projections, prompting doubts about whether the artificial intelligence firm can sustain its substantial data center investments, according to a Wall Street Journal article published on Monday.

Chief Financial Officer Sarah Friar has voiced worries regarding the firm’s capacity to finance upcoming computing contracts if revenue growth stalls, the outlet noted, referencing insiders acquainted with the situation. Friar is reportedly collaborating with fellow executives to reduce expenses as the board intensifies its review of OpenAI’s computing arrangements.

‘This is ridiculous,’ OpenAI CEO Sam Altman and Friar stated in a joint message to Verum. ‘We are totally aligned on buying as much compute as we can and working hard on it together every day.’

Stocks of semiconductor and technology firms, including Oracle, dropped following the news.

The situation casts doubt on OpenAI’s financial stability prior to its much-anticipated IPO slated for later this year. Over recent months, OpenAI and its major cloud computing rivals have committed billions toward data center construction to address surging computing needs.

Several of these agreements are directly linked to OpenAI. Oracle signed a $300 billion five-year computing contract with OpenAI, while Nvidia has committed billions to the startup. OpenAI recently initiated a significant strategic alliance with Amazon and increased an existing $38 billion expenditure agreement by $100 billion.

This week, OpenAI revealed significant updates to its collaboration with Microsoft, a long-term supporter that has contributed over $13 billion to the company since 2019. Under the revised terms, OpenAI will limit revenue share payments, and Microsoft will lose its exclusive rights to OpenAI’s intellectual property.

Read the full report from The Wall Street Journal.

Continue Reading

Technologies

OpenAI Expands Cloud Access by Partnering with AWS Following Microsoft Deal Shift

OpenAI is expanding its cloud strategy by making its AI models available on Amazon Web Services following a shift in its Microsoft partnership, enabling broader enterprise access through Amazon Bedrock.

Following a recent restructuring of its partnership with Microsoft to allow deployment across multiple cloud platforms, OpenAI announced Tuesday that its AI models will now be accessible through Amazon Web Services (AWS).

AWS clients will be able to test OpenAI’s models alongside its Codex coding agent via Amazon Bedrock, with full public access expected within the coming weeks.

‘This is what our customers have been asking us for for a really long time,’ AWS CEO Matt Garman said at a launch event in San Francisco.

Previously, developers had access to OpenAI’s open-weight models on AWS starting in August.

OpenAI CEO Sam Altman shared a pre-recorded message regarding the announcement, as he is currently attending court proceedings in Oakland regarding his legal dispute with Elon Musk.

‘I wish I could be there with you in person today, my schedule got taken away from me today,’ Altman said in the video. ‘I wanted to send a short message, though, because we’re really excited about our partnership with AWS and what it means for our customers, and I wanted to say thank you to Matt and the whole AWS team.’

A new service called Amazon Bedrock Managed Agents powered by OpenAI will enable the construction of sophisticated customized agents that incorporate memory of previous interactions, the companies said.

Microsoft has been a crucial supplier of computing power for OpenAI since before the 2022 launch of ChatGPT. Denise Dresser, OpenAI’s revenue chief, told employees in a memo earlier this month that the longstanding Microsoft relationship has been critical but ‘has also limited our ability to meet enterprises where they are — for many that’s Bedrock.’

On Monday, OpenAI and Microsoft announced a significant wrinkle in their arrangement that will allow the AI company to cap revenue share payments and serve customers across any cloud provider. Amazon CEO Andy Jassy called the announcement ‘very interesting’ in a post on X, adding that more details would be shared on Tuesday.

OpenAI and Amazon have been getting closer in other ways.

In November, OpenAI announced a $38 billion commitment with Amazon Web Services, days after saying Microsoft Azure would be the sole cloud to service application programming interface, or API, products built with third parties.

Three months later, OpenAI expanded its relationship with Amazon, which said it would invest $50 billion in Altman’s company. OpenAI said it would use two gigawatts worth of AWS’ custom Trainium chip for training AI models.

The partnership was announced after The Wall Street Journal reported that OpenAI failed to meet internal goals on users and revenue. Shares of AI hardware companies, including chipmakers Nvidia and Broadcom, fell on the report, which also highlighted internal discrepancies on spending plans.

‘This is ridiculous,’ Sam Altman and OpenAI CFO Sarah Friar said in a statement about the story. ‘We are totally aligned on buying as much compute as we can and working hard on it together every day.’

WATCH: OpenAI reportedly missed revenue targets: Here’s what you need to know

Continue Reading

Trending

Copyright © Verum World Media