Technologies
CRISPR startup wants to resurrect the woolly mammoth by 2027
Colossal has landed $15m in funding to restore the woolly mammoth to the Arctic — and it thinks it can birth calves in four to six years.
You’ve heard of startups building computer chips, delivery drones and social networks. One called Colossal has a very different goal: bringing the woolly mammoth back from extinction by 2027 using CRISPR, a revolutionary gene editing technology.
The plan isn’t to re-create true woolly mammoths exactly but rather to bring their cold-adapted genetic traits like small ears and more body fat to their elephant cousins, creating a hybrid that can wander the tundra where mammoths haven’t been seen for 10,000 years. Colossal’s co-founders are Chief Executive Ben Lamm, who started five companies before this, and George Church, a Harvard Medical School professor with deep CRISPR expertise.
«Our true North Star is a successful restoration of the woolly mammoth, but also its successful rewilding into interbreeding herds in the Arctic,» Lamm said. «We’re now focusing on having our first calves in the next four to six years.»
It’s an interesting illustration of an imperative sweeping the tech world: Don’t just make money, help the planet too. Tesla’s mission is to electrify transport to get rid of fossil fuels that hurt Earth. Bolt Threads wants to replace leather with a fungal fiber-based equivalent that’s easier on the environment than animal agriculture. Colossal hopes its work will draw attention to biodiversity problems and ultimately help fix them.
Colossal has raised $15 million so far, led by investment firm Tulco. The startup’s 19 employees work at its Dallas headquarters and in offices in Boston and Austin, Texas, and it’s using its funds to hire more.
Artificial wombs and other technology spinoffs
Church said he expects spinoffs from the company’s biotechnology and genetics work.
«The pipeline of large scale genome engineering techniques can be applied to many other applications beyond de-extinction, and therefore [are] most promising for commercialization,» he said.
One technology ripe for commercialization is multiplex genome engineering, a technique Church helped develop that speeds genetic editing by making multiple changes to DNA at once.
Colossal also hopes to develop artificial wombs to grow its mammoth embryos. Just growing 10 woolly mammoths with surrogate elephant mothers isn’t enough to get to the large-scale herds the company envisions.
At the foundation of Colossal’s work is CRISPR. This technology, adapted from a method bacteria evolved to identify attacking viruses and chop up their DNA, is now a mainstay of genetic engineering, and Church has been involved since CRISPR’s earliest days.
Jurassic Park-style tourism? Nope
Selling or licensing spinoff technology is a somewhat indirect way of running a business. A more direct option is selling tickets to tourists. After all, humans already pay lots of money to see charismatic megafauna like lions, elephants and giraffes on African safaris. Seeing a creature that’s been gone for 10,000 years could add to the excitement.
But that’s not Colossal’s game plan. «Our focus is on species preservation and protection of biodiversity right now, not in putting them in zoos,» Lamm said. By re-creating woolly mammoths, Colossal can preserve the genetic legacy of Asian elephants that now are endangered.
Another candidate species Colossal wants to re-create is the woolly rhinoceros, a relative to the critically endangered Sumatran rhino.
Although Colossal doesn’t plan to build a tourist destination, it does have a woolly mammoth rewilding site in mind that sounds awfully close to Jurassic Park: Pleistocene Park. This area of about 60 square miles in northern Russia, named after the geologic period that ended with the last ice age, is where researchers Sergey and Nikita Zimov are trying to test their theories about the ecological and climatic effects of rewilding.
One Zimov idea is that woolly mammoths will trample snow and knock down trees. That, in turn, will restore grasslands that reflect more of the sun’s warming rays and eliminate insulating snow and forests so the ground cools more. And that means the ground will stay frozen instead of releasing its current store of carbon dioxide and methane greenhouse gases. About 260 billion to 300 billion metric tons of carbon could be released from thawing permafrost by 2300, scientists calculate, exacerbating the weather extremes and other problems caused by climate change.
Is species de-extinction a good idea?
There’s an appeal to the idea of de-extinction. Humans have dramatically altered the planet, and the United Nations estimates we threaten 1 million species with extinction as a result.
Colossal hopes its work will raise more attention to the biodiversity collapse. And it also plans to create detailed genetic descriptions of many endangered species «so we have the recipe if that species does go extinct,» Lamm said.
But is that really the best use of our resources to help the planet? No, some researchers believe.
Resurrecting species could have some benefits, but money would be better spent on trying to protect ones that are still around, a group of biologists argued in one paper published in Nature Ecology & Evolution. «Potential sacrifices in conservation of extant species should be a crucial consideration in deciding whether to invest in de-extinction or focus our efforts on extant species,» the researchers wrote.
But this isn’t government money Colossal is talking about, and Lamm argues that his startup’s work complements other conservation efforts. And, he argues, startups can move faster than government-funded work.
In a world dominated by climate crisis headlines, a startup that makes money with an ecosystem-improvement focus has special appeal. One investor, Zack Lynch of Jazz Venture Partners, is excited by software, hardware and biotech he expects Colossal will create.
At the same time, «these breakthroughs will help address issues such as land degradation, animal pollinator loss and other negative biodiversity trends,» Lynch said. Given how big our environmental problems are, you can see why an investor might be interested.
Technologies
Google races to put Gemini at the center of Android before Apple’s AI reboot
Google is using its latest Android rollout to position Gemini as the AI layer across phones, Chrome, laptops and cars.
Google is using its latest Android rollout to make Gemini less of a chatbot and more of an operating layer across the phone, browser, car and laptop, just weeks before Apple is expected to show its own Gemini-powered Apple Intelligence reboot at WWDC.
Ahead of its Google I/O developer conference next week, the company previewed a number of Android updates, including AI-powered app automation, a smarter version of Chrome on Android, new tools for creators, a redesigned Android Auto experience, and a sweeping set of new security features.
Alphabet is counting on Gemini to help Google compete directly with OpenAI and Anthropic in the market for artificial intelligence models and services, while also serving as the AI backbone across its expansive portfolio of products, including Android. Meanwhile, Gemini is powering part of Apple’s new AI strategy, giving Google a role in the iPhone maker’s reset even as it races to prove its own version of personal AI on the phone is further along.
Sameer Samat, who oversees Google’s Android ecosystem, told CNBC that Google is rebuilding parts of Android around Gemini Intelligence to help users complete everyday tasks more easily.
“We’re transitioning from an operating system to an intelligence system,” he said.
As part of Tuesday’s announcements. Google said Gemini Intelligence will be able to move across apps, understand what’s on the screen and complete tasks that would normally require a user to jump between multiple services. That means Android is moving beyond the traditional assistant model, where users ask a question and get an answer, and acting more like an agent.
For instance, Google says Gemini can pull relevant information from Gmail, build shopping carts and book reservations. Samat gave the example of asking Gemini to look at the guest list for a barbecue, build a menu, add ingredients to an Instacart list and return for approval before checkout.
A big concern surrounding agentic AI involves software taking action on a user’s behalf without permissions. Samat said Gemini will come back to the user before completing a transaction, adding, “the human is always in the loop.”
Four months after announcing its Gemini deal with Google, Apple is under pressure to show a more capable version of Apple Intelligence, which has been a relative laggard on the market. Apple has long framed privacy, hardware integration and control of the user experience as its advantages.
Google’s Android push is designed to show it can bring AI deeper into the device experience while still giving users control over what Gemini can see, where it can act and when it needs confirmation.
The app automation features will roll out in waves, starting with the latest Samsung Galaxy and Google Pixel phones this summer, before expanding across more Android devices, including watches, cars, glasses and laptops later this year.
The company is also redesigning Android Auto around Gemini, turning the car into another major surface for its assistant. Android Auto is in more than 250 million cars, and Google says the new release includes its biggest maps update in a decade and Gemini-powered help with tasks like ordering dinner while driving.
Alphabet’s AI strategy has been embraced by Wall Street, which has pushed the company’s stock price up more than 140% in the past year, compared to Apple’s roughly 40% gain. Investors now want to see how Gemini can become more central to the products people use every day.
WATCH: Alphabet briefly tops Nvidia after report of $200 billion Anthropic cloud deal
Technologies
Waymo recalls 3,800 robotaxis after glitch allowed some vehicles to ‘drive into standing water’
Waymo issued a voluntary recall of about 3,800 of its robotaxis to fix software issues that could allow them to drive into flooded roadways.
Waymo is recalling about 3,800 robotaxis in the U.S. to fix software issues that could allow them to “drive onto a flooded roadway,” according to a letter on the National Highway Traffic Safety Administration’s website.
The voluntary recall is for Waymo vehicles that use the company’s fifth and sixth generation automated driving systems (or ADS), the U.S. auto safety regulator said in the letter posted Tuesday.
Waymo autonomous vehicles in Austin, Texas, were seen on camera driving onto a flooded street and stalling, requiring other drivers to navigate around them. It’s the latest example of a safety-related issue for the Alphabet-owned AV unit that’s rapidly bolstering its fleet of vehicles and entering new U.S. markets.
Waymo has drawn criticism for its vehicles failing to yield to school buses in Austin, and for the performance of its vehicles during widespread power outages in San Francisco in December, when robotaxis halted in traffic, causing gridlock.
The company said in a statement on Tuesday that it’s “identified an area of improvement regarding untraversable flooded lanes specific to higher-speed roadways,” and opted to file a “voluntary software recall” with the NHTSA.
“Waymo provides over half a million trips every week in some of the most challenging driving environments across the U.S., and safety is our primary priority,” the company said.
Waymo added that it’s working on “additional software safeguards” and has put “mitigations” in place, limiting where its robotaxis operate during extreme weather, so that they avoid “areas where flash flooding might occur” in periods of intense rain.
WATCH: Waymo launches new autonomous system in Chinese-made vehicle
Technologies
Qualcomm tumbles 13% as semiconductor stocks retreat from historic AI-fueled surge
Semiconductor equities reversed sharply after a broad AI-driven advance, with Qualcomm suffering its worst day since 2020 amid inflation concerns and rising oil prices.
Semiconductor stocks fell sharply on Tuesday, reversing course after an extensive rally that had expanded the artificial intelligence investment theme well past Nvidia and driven the industry to unprecedented levels.
Qualcomm plunged 13% and was on track for its steepest single-day decline since 2020. Intel shed 8%, while On Semiconductor and Skyworks Solutions each lost more than 6%. The iShares Semiconductor ETF, which benchmarks the overall sector, fell 5%.
The sell-off came after a key gauge of consumer prices came in above forecasts, and as conflict in Iran pushed crude oil higher—prompting investors to shift away from riskier assets.
The preceding advance had widened the AI opportunity set beyond longtime industry leader Nvidia, which for much of the past several years had largely carried the market to new peaks on its own.
Explosive appetite for central processing units, along with the graphics processing units that power large language models, has sent chipmakers to all-time highs.
Market participants are wagering that the shift from AI model training to autonomous agents will lift demand for additional AI hardware. Among the beneficiaries are memory chip producers, which are raising prices as supply remains tight.
Micron Technology slid 6%, and Sandisk cratered 8%. Sandisk’s stock has surged more than six times over since January.
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