Technologies

Delta variant: Could COVID vaccine boosters be here sooner than we thought?

With breakthrough infections in fully vaccinated people, the debate is over whether booster shots are needed to protect against the highly contagious strain.

For the most up-to-date news and information about the coronavirus pandemic, visit the WHO and CDC websites.

During the third week of July, the World Health Organization reported a 131% increase in new COVID cases in the US. With the delta variant of the coronavirus becoming the dominant strain, pharmaceutical giant Pfizer said it’s working on a booster shot for its COVID-19 vaccine. To prepare for the possibility, the US Centers for Disease Control and Prevention said it’s weighing a third shot for immune-compromised people.

In a July 8 press release, Pfizer said a third shot of its vaccine would enhance the immunity of those who’ve already received the first two vaccine shots. In addition to creating a booster for its existing vaccine, the drugmaker said it would formulate a new version of its COVID-19 vaccine to target the delta variant. The CDC and the Food and Drug Administration responded with a joint statement the same day saying that fully vaccinated Americans «do not need a booster shot at this time.»

But that was all before the CDC’s most recent internal document confirmed in late July that vaccinated people can both contract the highly contagious delta variant and easily spread it. Those recent findings were behind the CDC’s shift in its mask guidance, which now recommends indoor mask use for everyone in areas with high transmission rates. The debate over mask use and vaccine boosters underscores how scientists and other health experts continue to grapple with the uncertainties of COVID-19.

Here’s what we know about Pfizer’s plans for a booster, and why the CDC and FDA caution against it, at least for now.

What are Pfizer’s plans for a COVID-19 booster shot?

Along with Moderna, Pfizer’s current two-dose vaccine provides effective protection against all known variants of COVID-19, including the delta variant. Studies have shown the Pfizer vaccine to be over 90% effective against the virus. But Pfizer also said its own research showed a third booster of its current vaccine increased antibody levels five to 10 times higher over its two-dose shots. The company noted its results have not been published or peer-reviewed.

Pfizer said it believes the level of protection the two doses of its vaccine provide can decrease over time, and a third booster dose may be needed «within six to 12 months» after a person is fully vaccinated. To prepare for the booster, Pfizer is testing both the effectiveness of a third dose of its current vaccine and working on an updated version targeting the delta variant. Pfizer said it would begin clinical trials on the booster this month as it seeks approval from government regulators for a third dose.

The company says a third shot given at least six months after the second shot in its original vaccine series would enhance protection against the delta variant, which has been known to infect fully vaccinated people.

What are the CDC and FDA saying in response?

«People who are fully vaccinated are protected from severe disease and death, including from the variants currently circulating in the country such as Delta,» the CDC and FDA said in a July 8 joint statement, without naming Pfizer. The government agencies emphasized the need for all eligible people to receive full doses of one of the approved vaccines, all of which are free.

The CDC and FDA said the question of a booster requires extensive scientific data and doesn’t depend on the input from pharmaceutical companies alone. «Virtually all COVID-19 hospitalizations and deaths are among those who are unvaccinated,» the statement mentioned, adding that the agencies will approve booster doses «if and when the science demonstrates that they are needed.»

According to a July 23 article in The New York Times, there is a growing consensus among Biden administration health officials that older individuals and those with compromised immune systems may, in fact, need a third shot. The same article notes that the CDC is exploring options to administer third doses even prior to authorization.

Is Moderna also planning to develop a booster shot?

While scientists and public health officials continue to study if those who are fully vaccinated will need a booster shot, Moderna said — along with Pfizer — it is moving ahead and exploring the need for a third shot.

Would the booster shot be free?

The current one-dose vaccine shot from Johnson & Johnson and two-dose versions from Moderna and Pfizer are free to anyone who wants to get vaccinated. According to the Biden administration, COVID-19 booster shots will also be free, if and when they’re approved.

Is it a good idea to mix and match COVID vaccines?

The CDC doesn’t recommend mixing and matching vaccines from the different makers, saying it hasn’t evaluated the effectiveness of mixing vaccine doses and that the «vaccines are not interchangeable.»

However, other global health agencies and countries are testing administered vaccines from two different manufacturers. In England, for example, a recent study found that those who received a first dose of the AstraZeneca vaccine and a second of Pfizer had a higher immune response than those who received two doses of the AstraZeneca vaccine.

While we wait to see how the situation develops, here’s what we know about the delta variant, more about COVID-19 boosters and if you need to continue to wear a mask.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

Technologies

We Played Nintendo Switch 2: Mario, Donkey Kong, Mouse, Camera and a Lot More

Technologies

Nintendo Switch 2: Every Reveal About the Console, New Games, Price, Release Date

The $450 console launches June 5, with Mario Kart World the highlight of its launch day game lineup.

The Nintendo Switch 2 console’s biggest reveal yet arrived Wednesday as part of the company’s latest Nintendo Direct event. This teed up a day of Switch 2 reveals that include its June 5 release date, a $450 price, its specs and its initial game lineup that extends from launch into 2026.

The console will be further buoyed by having Mario Kart World as a launch title, which will go on sale in either a $500 bundle with the Switch 2 or on its own for $80 — making the open-world racing game one of Nintendo’s most expensive yet. Other games announced, such as Donkey Kong Bananza, are being priced around $70, which matches the cost of 2023’s The Legend of Zelda: Tears of the Kingdom. That Zelda game and Breath of the Wild are among the original Switch titles that will get enhanced Nintendo Switch 2 Edition upgrades, a premium upgrade allowing players to get new features, modes and graphical enhancements that take advantage of the newer system’s capabilities.

Here are the top highlights from Nintendo’s console event, all of the games we’ve heard about so far (including new titles, Nintendo Switch 2 Editions and GameCube games coming to Nintendo Switch Online) and all of our coverage so far. You can also check out our Nintendo Switch 2 live blog for even more updates about the Switch 2 as we learn them.

Nintendo Switch 2 console

The Nintendo Switch 2’s specs saw a noticeable technical bump over the Switch. The Nintendo Switch 2 has a 7.9-inch, 1080p resolution LCD that supports a 120Hz refresh rate — matching what we now see on most Android phones. When the Switch 2 is docked, compatible games can run in 4K resolution. The new dock also includes a cooling fan.

The Switch 2 comes with 256GB of internal storage, and the new Switch 2 Game Cards will load games faster. For digital libraries, however, the Switch 2 will only work with microSD Express cards, which are different from the microSD cards that are compatible with the prior Nintendo Switch. Nintendo will have a Software Transfer feature available to help move games and data from the original Switch to the Switch 2.

The new Joy-Con for the controllers will support mouse controls, and a new C button will be part of a new GameChat communication feature that allows both voice and video chat. There’s also a Nintendo Switch 2 Camera, allowing players to see each other.

The Switch 2 also adds a second USB-C port to the top of the system, which Nintendo says can help connect its new camera accessory or charge the console when playing in tabletop mode. Nintendo also revealed a new Switch 2 Pro Controller with the C button and customizable GL and GR buttons on the back.

Following the presentation, Nintendo unveiled the system’s price of $450 in the US. It will also sell the Switch 2 bundled with a digital version of Mario Kart World for $500.

Mario Kart World

Mario Kart World removes its traditional boundaries and lets drivers roam freely across an entire world of race courses. The game will get its own Nintendo Direct later this month, where we’ll see additional details, but we already know it’ll include traditional races and a Free Roam mode, much like in the Forza Horizon series.

Getting the game bundled for an extra $50 on the cost of the Switch 2 might be the move if you are interested in the game, because Nintendo announced on its website that standalone copies of Mario Kart World will cost $80.

Joy-Con 2 C button and GameChat

Nintendo’s rolling out its new C button across several new Switch 2 controllers. The button will be used for the new GameChat communication features without a headset. The button will be used alongside a microphone on the console itself, which Nintendo says can be used whether it’s docked to a TV or in handheld mode.

In its teaser video, Nintendo promises the microphone will be able to cancel out loud background noises. GameChat will also work with a Nintendo Switch 2 Camera, allowing video chat and various camera-based game modes in supported titles. GameChat will be free at launch through March 31, 2026.

Nintendo Switch 2 Edition games upgrade titles

The Nintendo Switch 2 will play three types of games: original Switch games, Switch 2 games and Switch 2 Edition games that will receive substantial enhancements. For many of these Switch 2 Edition games, you’ll need to buy an upgrade pack if you own the original for Switch. Many of them will get more than just enhanced graphics in the upgrade; for example, Super Mario Party Jamboree will get new games that support the new Joy-Cons’ mouse controls, audio recognition and video camera gameplay options through the Switch 2 Camera.

Other Nintendo Switch games that are getting Switch 2 Edition options include The Legend of Zelda Breath of the Wild, The Legend of Zelda Tears of the Kingdom, Kirby and the Forgotten Land, Metroid Prime 4 Beyond and Pokemon Legends: Z-A. Enhancements vary: The Zelda games will start working with a companion phone app for maps and sending schematics to friends, while Kirby will get a new story that’s exclusive to the Switch 2 Edition. On the third-party side, Civilization 7 will get mouse controls.

Nintendo did not announce what upgrade packs will cost. However, some Switch games will get free updates that will improve performance or enhance features when playing them on the Switch 2. The Switch games getting these updates include:

Hyrule Warriors: Age of Imprisonment

Hyrule Warriors: Age of Imprisonment is a new game set in the world of Zelda that tells the story that leads into The Legend of Zelda: Tears of the Kingdom. This appears to be similar to how Hyrule Warriors: Age of Calamity told the story of a war that led to the events of Breath of the Wild. The teaser shows Zelda discovering that she’s arrived in the past of Hyrule, and the game will expand on how she gets involved in the corresponding Imprisonment War.

Nintendo Switch 2 games

Several other first- and third-party games were spotlighted during the Switch 2 Direct. These include Donkey Bananza, one of the first 3D platforming games featuring DK since 1999’s Donkey Kong 64. Kirby will also return to the racing genre in Kirby Air Riders, which comes more than 20 years after the GameCube racer Kirby’s Air Ride. DragXDrive will use mouse controls to control a futuristic wheelchair basketball game in which players will simulate push and pull motions to control their character.

An onslaught of Switch 2 third-party games were quickly shuffled through during the Direct, which I list below. An unnamed James Bond game is in development at Hitman studio IO Interactive, as is a darker title from Elden Ring creator FromSoftware called The Duskbloods, which will be exclusive to the Switch 2.

The full list of announced Nintendo Switch 2 games includes:

Borderlands 4
Bravely Default Flying Fairy HD Remaster
Cyberpunk 2077: Ultimate Edition
Daemon X Machina: Titanic Scion
Deltarune
Donkey Kong Bananza
Drag x Drive
EA Sports FC
EA Sports Madden NFL
Elden Ring Tarnished Edition
Enter the Gungeon 2
Fast Fusion
Final Fantasy 7 Remake Intergrade
Fortnite
Hades 2
Hitman World of Assassination — Signature Edition
Hogwarts Legacy
Hollow Knight: Silksong
Hyrule Warriors: Age of Imprisonment
Kirby Air Riders
Kirby and the Forgotten Land — Nintendo Switch 2 Edition and Star-Crossed World
Kunitsu-Gai: Path of the Goddess
Mario Kart World
Metroid Prime 4: Beyond — Nintendo Switch 2 Edition
NBA 2K
Nintendo Switch 2 Welcome Tour
Nobunaga’s Ambition: Awakening Complete Edition
Pokemon Legends: Z-A — Nintendo Switch 2 Edition
Project 007
Puyo Puyo Tetris 2S
Rune Factory: Guardians of Azuma — Nintendo Switch 2 Edition
Sid Meier’s Civilization 7 — Nintendo Switch 2 Edition
Split Fiction
Star Wars Outlaws
Starseeker: Astroneer Expeditions
Street Fighter 6
Super Mario Party Jamboree — Nintendo Switch 2 Edition and Jamboree TV
Survival Kids
The Duskbloods
The Legend of Zelda: Breath of the Wild — Nintendo Switch 2 Edition
The Legend of Zelda: Tears of the Kingdom — Nintendo Switch 2 Edition
Tony Hawk’s Pro Skater 3 and 4
WWE 2K
Yakuza 0 Definitive Edition

Among these titles, you can see the full list of June 5 Switch 2 launch day games here.

Nintendo GameCube library coming to Switch 2

The Nintendo Switch Online game library will add GameCube games to the Switch 2. On launch day, these games will initially include The Legend of Zelda: The Wind Waker, SoulCalibur 2 and F-Zero GX, with each game getting enhanced graphics. Online multiplayer will also be added to certain titles. Super Mario Sunshine, Super Mario Strikers and Luigi’s Mansion are among the games set to arrive later. At launch, Nintendo will also sell a GameCube controller, which will be wireless and include a C button for GameChat.