Technologies

Delta variant: Could COVID vaccine boosters be here sooner than we thought?

With breakthrough infections in fully vaccinated people, the debate is over whether booster shots are needed to protect against the highly contagious strain.

For the most up-to-date news and information about the coronavirus pandemic, visit the WHO and CDC websites.

During the third week of July, the World Health Organization reported a 131% increase in new COVID cases in the US. With the delta variant of the coronavirus becoming the dominant strain, pharmaceutical giant Pfizer said it’s working on a booster shot for its COVID-19 vaccine. To prepare for the possibility, the US Centers for Disease Control and Prevention said it’s weighing a third shot for immune-compromised people.

In a July 8 press release, Pfizer said a third shot of its vaccine would enhance the immunity of those who’ve already received the first two vaccine shots. In addition to creating a booster for its existing vaccine, the drugmaker said it would formulate a new version of its COVID-19 vaccine to target the delta variant. The CDC and the Food and Drug Administration responded with a joint statement the same day saying that fully vaccinated Americans «do not need a booster shot at this time.»

But that was all before the CDC’s most recent internal document confirmed in late July that vaccinated people can both contract the highly contagious delta variant and easily spread it. Those recent findings were behind the CDC’s shift in its mask guidance, which now recommends indoor mask use for everyone in areas with high transmission rates. The debate over mask use and vaccine boosters underscores how scientists and other health experts continue to grapple with the uncertainties of COVID-19.

Here’s what we know about Pfizer’s plans for a booster, and why the CDC and FDA caution against it, at least for now.

What are Pfizer’s plans for a COVID-19 booster shot?

Along with Moderna, Pfizer’s current two-dose vaccine provides effective protection against all known variants of COVID-19, including the delta variant. Studies have shown the Pfizer vaccine to be over 90% effective against the virus. But Pfizer also said its own research showed a third booster of its current vaccine increased antibody levels five to 10 times higher over its two-dose shots. The company noted its results have not been published or peer-reviewed.

Pfizer said it believes the level of protection the two doses of its vaccine provide can decrease over time, and a third booster dose may be needed «within six to 12 months» after a person is fully vaccinated. To prepare for the booster, Pfizer is testing both the effectiveness of a third dose of its current vaccine and working on an updated version targeting the delta variant. Pfizer said it would begin clinical trials on the booster this month as it seeks approval from government regulators for a third dose.

The company says a third shot given at least six months after the second shot in its original vaccine series would enhance protection against the delta variant, which has been known to infect fully vaccinated people.

What are the CDC and FDA saying in response?

«People who are fully vaccinated are protected from severe disease and death, including from the variants currently circulating in the country such as Delta,» the CDC and FDA said in a July 8 joint statement, without naming Pfizer. The government agencies emphasized the need for all eligible people to receive full doses of one of the approved vaccines, all of which are free.

The CDC and FDA said the question of a booster requires extensive scientific data and doesn’t depend on the input from pharmaceutical companies alone. «Virtually all COVID-19 hospitalizations and deaths are among those who are unvaccinated,» the statement mentioned, adding that the agencies will approve booster doses «if and when the science demonstrates that they are needed.»

According to a July 23 article in The New York Times, there is a growing consensus among Biden administration health officials that older individuals and those with compromised immune systems may, in fact, need a third shot. The same article notes that the CDC is exploring options to administer third doses even prior to authorization.

Is Moderna also planning to develop a booster shot?

While scientists and public health officials continue to study if those who are fully vaccinated will need a booster shot, Moderna said — along with Pfizer — it is moving ahead and exploring the need for a third shot.

Would the booster shot be free?

The current one-dose vaccine shot from Johnson & Johnson and two-dose versions from Moderna and Pfizer are free to anyone who wants to get vaccinated. According to the Biden administration, COVID-19 booster shots will also be free, if and when they’re approved.

Is it a good idea to mix and match COVID vaccines?

The CDC doesn’t recommend mixing and matching vaccines from the different makers, saying it hasn’t evaluated the effectiveness of mixing vaccine doses and that the «vaccines are not interchangeable.»

However, other global health agencies and countries are testing administered vaccines from two different manufacturers. In England, for example, a recent study found that those who received a first dose of the AstraZeneca vaccine and a second of Pfizer had a higher immune response than those who received two doses of the AstraZeneca vaccine.

While we wait to see how the situation develops, here’s what we know about the delta variant, more about COVID-19 boosters and if you need to continue to wear a mask.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

Technologies

Despite War of Words, Trump May Funnel Billions to Musk’s Starlink With BEAD Changes

Technologies

Square Enix’s Next Game Blends Among Us-Like Murder Mystery With Bloody Carnage

Unveiled at Summer Game Fest, Killer Inn is an upcoming multiplayer murder mystery pitting players against each other in the search for the true killers.

Bet you didn’t have this one on your bingo list. Developed by Tactic Studios in partnership with Square Enix, the game was unveiled during the Summer Game Fest livestream, and it’s far from the famed RPG maker’s bread and butter. Killer Inn, as it’s called, is a multiplayer murder mystery that takes Among Us-like gameplay and ratchets it up by handing players knives, guns and many other weapons to kill or be killed while they search for the original killer.

Killer Inn might be one of those games that is best understood after playing a few matches, but even from the reveal trailer, there’s a lot going on. In each match, 24 players enter a sprawling castle-turned-hotel to determine who the real killers are as they’re picked off one by one. There’s deduction and mayhem aplenty.

Killer Inn’s play phases are patterned after detective-style games, from Among Us to Ultimate Werewolf to Mafia. A match begins with most players as cooperative participants («lambs,» in Killer Inn’s parlance) mixed with a few secret killers («wolves»). Players complete tasks to earn tokens redeemable for items and weapons, while the killers quietly go about their business — until someone discovers a body. On the corpse are clues left by the killer, so the lambs can try deducing the true culprit (or culprits).

Then it’s all about collecting clues and identifying the wolves — but unlike Among Us, there’s no group discussion to present evidence or vote them out. Killer Inn skips the parlor scene and dives straight into action: If you’re sure someone’s the killer, take them out. Use those token-bought guns and blades to put down the villain. Unless you accidentally murder one of your innocent teammates — in which case, you’re turned to stone for the rest of the match. Bummer.

Lambs have another win condition: assembling four keys to escape on the ship that brought them to the murder island. There are other mechanics, too, like finding relative safety in rooms with hotel staff, who will identify any wolves that kill lambs in their line of sight.

Players can choose between 25 premade characters that each have their own unique appearances and abilities, the latter of which improve as the match goes on, often reflecting the nefarious dark sides of the participants. For example, Winston is a surgeon who kills more efficiently with knives and, when leveled up, deals extra damage while covered in blood. The Otaku, by contrast, gains 25 HP from finding clues and eventually builds resistance to status effects. Levels don’t carry over between matches — everyone starts fresh at level one.

Killer Inn doesn’t have a release date, but the game will kick off a closed beta test over Steam in the near future.

Technologies

Resident Evil 9 Revealed at Summer Game Fest After Early Fake-Out

Resident Evil Requiem is the next entry in Capcom’s survival horror series.

After a fake-out earlier in Summer Game Fest on Friday, Resident Evil Requiem, or Resident Evil 9, was shown for the first time.

The new title is the first mainline entry since Capcom released Resident Evil Village in 2021, and is rumored to feature series stalwart Leon Kennedy. In the trailer, the only person we saw was a character named Grace Ashcroft, who works for the FBI and appears to have ties to Raccoon City.

For the most hardcore Resident Evil fans, the name Ashcroft will ring a bell. Alyssa Ashcroft was one of the survivors of the online-only title, Resident Evil Outbreak for the PS2. Alyssa was a journalist who was trapped in Raccoon City during the events of Resident Evil 2, and she, along with other survivors, had to escape the city before it was destroyed.

Grace is Alyssa’s daughter, and in the trailer, she is going to visit the Remwood Hotel, where Alyssa was murdered. Later in the trailer, images from what appears to be the remnants of a destroyed Raccoon City are shown, so it appears Resident Evil 9 will return to where the series started.

Leon’s return is a big deal for the series, which has made some of its best games with him in the starring (or co-starring) role. He first showed up as a rookie cop in Resident Evil 2, which built on the original game’s success with more story and improved monsters and level design.

He showed up again in Resident Evil 4, which took the series in a new direction by introducing an over-the-shoulder perspective, instead of the usual static camera angles and tank controls. Leon was also one of several playable protagonists in Resident Evil 6, a game that seemed to forget about its survival horror roots. We mostly don’t talk about that one.

But the 2019 remake of Resident Evil 2 was an excellent return to form, bringing RE4’s gameplay and much better graphics to a fan-favorite entry. The RE4 remake was a similar success.

Resident Evil Requiem is set to drop Feb. 27, 2026, for PC, PS5 and Xbox Series consoles, but we’re hoping to get our hands on it this weekend. If you want to catch up on older Resident Evil games, Capcom is having a sale that includes basically all the games, including Village and the three remakes.