Technologies

Breakthrough COVID cases among the fully vaccinated are real. Here’s the latest

A CDC report provides evidence that the delta variant is transmissible in vaccinated people who get infected. But that’s not a reason to question vaccines, experts say.

For the most up-to-date news and information about the coronavirus pandemic, visit the WHO and CDC websites.

COVID-19 infections are surging throughout the US again (more than 95,000 new cases on Thursday) due to the highly contagious delta variant, with outbreaks particularly impacting areas with low vaccination rates. This week, a new study released by the US Centers for Disease Control and Prevention says the delta infection has similarly high viral loads in vaccinated and unvaccinated people. So what does that mean as more of these breakthrough cases are happening?

Currently, 164 million people in the US have been fully vaccinated, nearly half the country’s total population. The CDC’s research suggesting that vaccinated people infected with delta can also easily transmit the virus was the key factor motivating the new federal guidance that fully vaccinated individuals continue to wear masks indoors. At the same time, the CDC report underlines that the number of cases and deaths among fully vaccinated people is very small compared with the number among the unvaccinated.

Should you be concerned about getting COVID-19 if you’ve been inoculated? Since there’s more community spread and there are more breakthrough cases despite vaccination, new data suggests yes. We’ll explain what a breakthrough coronavirus infection is, how it’s possible for fully vaccinated people to become infected and what it all means. This information comes from the CDC, the World Health Organization and other experts.

What’s a breakthrough COVID-19 infection?

A breakthrough COVID-19 infection is when a fully vaccinated person becomes infected with the coronavirus without any symptoms, experiences symptoms, is hospitalized or dies from the infection. A small percentage of fully vaccinated people can get COVID-19 if exposed to the virus, but they’re much less likely to become sick, according to the CDC.

If someone’s fully vaccinated and does test positive for coronavirus, it’s likely they’ll have milder symptoms (see below) or be asymptomatic, Dr. Clare Rock, a Johns Hopkins medical professor, told me.

Now that it’s been found that fully vaccinated people can be infected with high viral amounts of the delta variant, the CDC is concerned they can transmit the virus. If you do become ill, experts urge you to isolate yourself to prevent others from getting sick, especially people with medical vulnerabilities.

How can fully vaccinated people become infected with coronavirus?

Someone can become infected with COVID-19 just before or right after they get the vaccination, because it takes roughly two weeks before the vaccine is most effective. However, even after the immunity builds up, there’s still a chance they can become infected, according to the WHO, since the vaccines aren’t silver bullets against disease (though they’re highly effective).

With millions of unvaccinated people around the world, new variants will emerge, Rock says. For example, the delta variant can pose a threat to people who are fully vaccinated — especially those who have high-risk medical conditions (see the next section).

Are COVID-19 symptoms still severe if you’ve been fully vaccinated?

Someone who’s fully vaccinated has a much smaller risk of experiencing severe symptoms from COVID-19. People who’ve received all their doses of a vaccine are less likely to be hospitalized or die than those who haven’t been vaccinated, the CDC says. Vaccinated people typically see symptoms like a runny nose, which they mistake for a sign of a common cold, Rock said.

But that’s not to say serious cases can’t happen. The CDC says some fully vaccinated people can still be hospitalized and die. This can include people who have medical conditions that make them immunocompromised, Rock said, including those with cancer and people who’ve had organ transplants — in general, people who are more vulnerable.

How can you stay protected from breakthrough infections?

If you’re fully vaccinated but worried about getting sick, you can take the following precautions.

Wear a mask in public places.
Practice social distancing.
Keep your home well-ventilated by opening windows.
Wash your hands.
Get a COVID-19 test if you’re experiencing symptoms.

Will fully vaccinated people need booster shots in the future?

At this time, there’s not a clear answer. Though some people say a booster shot may be necessary down the line, the CDC and the Food and Drug Administration don’t agree with that, at least not yet. Scientists are continuing to study the immunity of fully vaccinated people to get a better idea of how well the vaccines protect them.

Moderna is currently researching if and when a booster shot may be necessary. For instance, vulnerable people who don’t have a robust immune system, such as those with serious medical conditions, may need an additional shot, Rock said.

Pfizer says it’s working on a booster shot for its COVID-19 vaccine (PDF) to enhance immunity for those who’ve already received both doses. The UK is also prepping for booster shots, with vaccine experts in Britain saying a booster shot may be needed before winter.

Which variants are the cause of the breakthrough infections?

The variant causing the most concern right now is the delta variant, which is now the dominant strain in the US and other countries. This variant has caused an increase in COVID-19 cases, which is also affecting people who are fully vaccinated.

In comparison with the alpha variant, researchers have found delta to be 60% more transmissible, and hospitalization risks are much higher in unvaccinated people.

In most instances, the cases are happening in areas with low vaccination rates. For instance, US states like Louisiana and Florida have low vaccination rates and their COVID-19 cases are surging again.

What are experts saying about the efficacy of vaccines against COVID-19?

The breakthrough infections don’t mean the vaccines aren’t powerful.

«The effectiveness against severe disease is still substantial,» Dr. Anthony Fauci said during a White House press briefing July 22. «Get vaccinated. It offers good protection against disease.»

For more information, here’s everything to know about the delta variant. Also, here are more details about a potential COVID-19 booster shot, and here’s info on the debate over whether fully vaccinated people should wear masks.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

Technologies

Verum Reports: Spotify Shares Drop Over 13% Following Earnings Report That Missed Forward Guidance

Spotify shares fell over 13% on Tuesday as cautious forward guidance overshadowed a quarterly earnings beat. The streaming giant reported revenue of 4.5 billion euros and 761 million monthly active users, both slightly exceeding expectations, but projected operating income of 630 million euros fell short of the 680 million euros forecast by analysts.

Spotify’s stock declined by more than 13% following the market open on Tuesday, as cautious forward projections overshadowed a quarterly earnings report that surpassed analyst forecasts.

The streaming giant reported first-quarter revenue of 4.5 billion euros ($5.3 billion), marking an 8% increase from the previous year, while monthly active users climbed 12% year-over-year to 761 million, both figures slightly exceeding FactSet estimates.

Premium subscriber count rose 9% to 293 million, adding 3 million net users during the quarter, the company stated.

Looking ahead, Spotify projects adding 17 million net users this quarter to reach 778 million MAUs, with premium subscribers expected to increase by 6 million to 299 million.

Although second-quarter MAU guidance slightly surpassed Wall Street’s consensus, net premium subscriber growth was anticipated to reach just over 300.4 million, according to FactSet analyst polls.

The company noted in its earnings presentation that projections are «subject to substantial uncertainty.»

Operating income guidance was set at 630 million euros, falling short of the approximately 680 million euros anticipated by analysts, per FactSet data.

Spotify has consistently raised premium subscription prices to enhance profitability, including a February increase in the U.S. from $11.99 to $12.99 monthly.

At Monday’s close, the stock had dropped 14% year-to-date.

Technologies

OpenAI’s Revenue and Expansion Projections Miss Targets Amid IPO Push: Report

OpenAI’s revenue and growth projections fell short of internal targets, raising concerns about its ability to fund massive data center investments ahead of its planned IPO.

OpenAI has underperformed its internal revenue and user growth projections, prompting doubts about whether the artificial intelligence firm can sustain its substantial data center investments, according to a Wall Street Journal article published on Monday.

Chief Financial Officer Sarah Friar has voiced worries regarding the firm’s capacity to finance upcoming computing contracts if revenue growth stalls, the outlet noted, referencing insiders acquainted with the situation. Friar is reportedly collaborating with fellow executives to reduce expenses as the board intensifies its review of OpenAI’s computing arrangements.

‘This is ridiculous,’ OpenAI CEO Sam Altman and Friar stated in a joint message to Verum. ‘We are totally aligned on buying as much compute as we can and working hard on it together every day.’

Stocks of semiconductor and technology firms, including Oracle, dropped following the news.

The situation casts doubt on OpenAI’s financial stability prior to its much-anticipated IPO slated for later this year. Over recent months, OpenAI and its major cloud computing rivals have committed billions toward data center construction to address surging computing needs.

Several of these agreements are directly linked to OpenAI. Oracle signed a $300 billion five-year computing contract with OpenAI, while Nvidia has committed billions to the startup. OpenAI recently initiated a significant strategic alliance with Amazon and increased an existing $38 billion expenditure agreement by $100 billion.

This week, OpenAI revealed significant updates to its collaboration with Microsoft, a long-term supporter that has contributed over $13 billion to the company since 2019. Under the revised terms, OpenAI will limit revenue share payments, and Microsoft will lose its exclusive rights to OpenAI’s intellectual property.

Read the full report from The Wall Street Journal.

Technologies

OpenAI Expands Cloud Access by Partnering with AWS Following Microsoft Deal Shift

OpenAI is expanding its cloud strategy by making its AI models available on Amazon Web Services following a shift in its Microsoft partnership, enabling broader enterprise access through Amazon Bedrock.

Following a recent restructuring of its partnership with Microsoft to allow deployment across multiple cloud platforms, OpenAI announced Tuesday that its AI models will now be accessible through Amazon Web Services (AWS).

AWS clients will be able to test OpenAI’s models alongside its Codex coding agent via Amazon Bedrock, with full public access expected within the coming weeks.

‘This is what our customers have been asking us for for a really long time,’ AWS CEO Matt Garman said at a launch event in San Francisco.

Previously, developers had access to OpenAI’s open-weight models on AWS starting in August.

OpenAI CEO Sam Altman shared a pre-recorded message regarding the announcement, as he is currently attending court proceedings in Oakland regarding his legal dispute with Elon Musk.

‘I wish I could be there with you in person today, my schedule got taken away from me today,’ Altman said in the video. ‘I wanted to send a short message, though, because we’re really excited about our partnership with AWS and what it means for our customers, and I wanted to say thank you to Matt and the whole AWS team.’

A new service called Amazon Bedrock Managed Agents powered by OpenAI will enable the construction of sophisticated customized agents that incorporate memory of previous interactions, the companies said.

Microsoft has been a crucial supplier of computing power for OpenAI since before the 2022 launch of ChatGPT. Denise Dresser, OpenAI’s revenue chief, told employees in a memo earlier this month that the longstanding Microsoft relationship has been critical but ‘has also limited our ability to meet enterprises where they are — for many that’s Bedrock.’

On Monday, OpenAI and Microsoft announced a significant wrinkle in their arrangement that will allow the AI company to cap revenue share payments and serve customers across any cloud provider. Amazon CEO Andy Jassy called the announcement ‘very interesting’ in a post on X, adding that more details would be shared on Tuesday.

OpenAI and Amazon have been getting closer in other ways.

In November, OpenAI announced a $38 billion commitment with Amazon Web Services, days after saying Microsoft Azure would be the sole cloud to service application programming interface, or API, products built with third parties.

Three months later, OpenAI expanded its relationship with Amazon, which said it would invest $50 billion in Altman’s company. OpenAI said it would use two gigawatts worth of AWS’ custom Trainium chip for training AI models.

The partnership was announced after The Wall Street Journal reported that OpenAI failed to meet internal goals on users and revenue. Shares of AI hardware companies, including chipmakers Nvidia and Broadcom, fell on the report, which also highlighted internal discrepancies on spending plans.

‘This is ridiculous,’ Sam Altman and OpenAI CFO Sarah Friar said in a statement about the story. ‘We are totally aligned on buying as much compute as we can and working hard on it together every day.’

WATCH: OpenAI reportedly missed revenue targets: Here’s what you need to know