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Moderna booster shot and omicron: 2 things we don’t know right now

The omicron variant of virus that causes COVID-19 is spreading across the US. What has Moderna said about the effectiveness of its vaccine and booster against the mutation?

For the most up-to-date news and information about the coronavirus pandemic, visit the WHO and CDC websites.

Saying “we underestimate this virus at our peril,” Tedros Adhanom, the director-general of the World Health Organization, said on Tuesday that “omicron is spreading at a rate we have not seen with any previous variant.” To underline the point, a preliminary study out of South Africa on Tuesday suggests that two doses of the Pfizer/BioNTech COVID-19 vaccine may be less effective against the new variant than delta, providing 33% protection.The study by Discovery, a South African health care organization, said the Pfizer vaccine may offer 70% protection against severe complications that result in hospitialization.

Moderna so far has not offered information on how effective its vaccine is against omicron. Moderna Chairman Noubar Afeyan said on Friday the omicron threat is to be taken seriously and his company should know more about the effectiveness of its vaccine this week against the variant.

The early information for US cases of the omicron variant appears to support the concern about weakened protection for those who are fully vaccinated with two doses of the Moderna and Pfizer vaccine or one of Johnson & Johnson. Rochelle P. Walensky, director of the Centers for Disease Control and Prevention, said on Friday that 80% of confirmed US cases with the mutated virus were fully vaccinated for the disease. And a third of the cases had received a booster, although some may have not been boosted in time to be fully protected before being infected with the omicron variant.

Omicron has pushed talk of a COVID booster to top of the page. As of Tuesday, over 24 million in the US have received the Moderna vaccine booster, according to the CDC, which may be key to being protected. “If you want to be optimally protected, you really should get a booster,” Dr. Anthony Fauci,the chief medical adviser to President Joe Biden, said on Sunday.

Scientists are still learning about the omicron variant, including how easily it can pass between people, how serious an infection it can cause and if it can evade immunity. As of Dec. 10, according to Jeff Zients, White House COVID-19 response coordinator, the US is administering 1.1 million booster shots a day, the most since May. The jump comes as the White House is stressing the need for COVID-19 vaccine heading into winter, including booster shots. (President Joe Biden’s campaign also includes “free” at-home COVID-19 test kits and stricter travel rules for international travelers.)

Health professionals believe that booster shots from Moderna and Pfizercould help slow COVID-19’s spread, reducing hospitalization and deaths, asthe effects of the vaccine weaken over time. The CDC urges booster shots for anyone over 18 six months after theirsecond dose of Moderna or Pfizer, or two months after getting asingle Johnson & Johnson dose.

The COVID-19 vaccines have proven so far to be highly effective in preventing hospitalization. People who are unvaccinated are 10 times more likely to be hospitalized if infected. With the federal vaccine mandate halted by a court order, Biden is turning to other measures to get booster shots administered. The government has also ordered 13 million courses of antiviral drugs in anticipation of higher caseloads this winter.

Here’s what you need to know about the Moderna booster, including doses, side effects and how to get a free ride. For more details, here’s the latest on COVID-19 vaccines for kids, how you can get a free COVID-19 test kit soon and what to know about breakthrough infections.

When will Moderna know how effective its COVID vaccine and booster is against the omicron?

The preliminary South Africa study presents an idea for how the Pfizer vaccine works with the omicron variant, it didn’t look at Moderna’s.

Moderna’s Afeyan on Friday told Fox News he expects to his company to have information on the effectiveness of its vaccine against the mutated variant this week. “We don’t have that data yet,” he said. “We are testing thoroughly all aspects of what we could do.”

“Our expectation,” he said, “is that a boosted person will be protected, certainly against serious disease and hospitalization.”

CNET asked Moderna for a comment but didn’t immediately get a response.

Pfizer has been more open about the effectiveness of its vaccine against the variant and said early lab results suggest that the first two doses of its vaccine might not fully protect against the variant and three doses may be needed to restore those protections.

When could we know if a COVID vaccine booster protects against the omicron variant?

A picture “Thethird shot … could not only dramatically increase the level ofprotection,” Fauci said on Sunday, “it very well increase the durabilityof protection.”Fauci said it will take study to study the booster toknow for sure.

Is Moderna making an omicron booster shot?

Scientists worry the omicron variant could spread more quickly than the now-dominant delta variant because of the number of mutations the new strain has compared with delta. Moderna is currently working on an omicron-specific booster vaccine, along with testing a COVID-19 vaccine that could protect against several mutated strains of the coronavirus.

Likeevery other vaccine-maker around the world, Moderna is testing theeffectiveness of its COVID-19 vaccine against omicron, but it may beweeks before lab tests show concrete evidence of how well Modernaprotects people from the new variant.

As part of its boostertesting, Moderna is also investigating whether a 100-microgram dose ofits booster provides better protection against the omicron variant — inother words, a third dose rather than a half dose as the booster iscurrently formulated now.

If Moderna needs to make a new vaccine modified for the variant, it could be available early in2022.

When is it time to get a COVID-19 vaccine booster shot?

If you got Moderna or Pfizer, six months after the date of your second shot listed on yourvaccination card is when you’re eligible to receive your booster dose.The CDC and other health authorities are now urging you to get yourbooster as soon as you’re eligible, to keep your immune response againstomicron, delta and other coronavirus variants as strong as possible.Two months after the Johnson & Johnson vaccine is the time for abooster (more below).

On Dec. 2, Biden also outlined a plan forMedicare to contact the 64 million people it serves and for AARP toreach out to its 38 million senior members. Pharmacies like Walgreens,CVS and RiteAid should also contact people who got a vaccine attheir retail stores when it’s time to schedule another dose.

Should people who are pregnant get a booster shot?

The COVID-19 booster recommendations apply to all people 18 years and older, including those who are pregnant. In fact, the CDC urges pregnant people to get a COVID-19 vaccine — and a booster is half a full vaccine dose.

“People who are pregnant or recently pregnant are more likely to get severely ill with COVID-19 compared with people who are not pregnant,” the CDC says on its website.

A recent study also linked COVID-19 infection in pregnant people to higher risk of stillbirth. However, there is no evidence that getting vaccinated decreases fertility in women or men.

Is the Moderna booster shot a third dose?

Booster shots of COVID-19 vaccines are currently half doses of the same vaccine used in the first two full shots. The goal is to top up the vaccine formula that reinforces the body’s immune response against the virus and its variants. The Moderna booster authorized by the CDC is a 50-microgram dose, while the first two shots were each 100 micrograms.

Moderna is also working on a combination shot that contains this year’s flu vaccine and its COVID-19 booster vaccine, but that’s not available right now.

How do I know which pharmacies have Moderna appointments?

Boosters are available at roughly 80,000 places across the country, including over 40,000 local pharmacies. Some 90% of Americans have a vaccine site within 5 miles of where they live.

A terrific free service in conjunction with the CDC sends you information when you text your ZIP code to this number: 438829. The response will show you COVID-19 vaccine locations in your area, along with the brand they carry for certain age groups, for instance, Moderna 18+. This can save you the trial and error of calling around, or showing up to your appointment to find that your booster of choice isn’t available. The text can also give you a shortcut to make your appointment right from your phone screen.

You can also check Vaccines.gov to see which vaccines are available where, and call 800-232-0233 for vaccine information.

How can I get a free ride to get my booster shot?

Lyft and Uber are offering free rides for some people who need them. An easy way to access those links for more information is through the text feature above You can also go to Lyft.com/vax or call Uber at: 855-921-0033.

Who can get a Moderna booster shot right now?

As of Nov. 19, all US adults — those age 18 and older — are eligible to get a booster shot of the COVID-19 vaccine. They qualify if it’s been at least six months since they’ve received a second dose of either the Moderna or Pfizer vaccine. Those who received the Johnson & Johnson vaccine are eligible for a booster dose after two months. Adults are encouraged to get whatever booster dose is available to them, even if that means mixing and matching vaccine boosters (more below), in other words, getting a different booster shot than their original vaccination.

What are the side effects of Moderna’s booster?

According to the CDC, those who got the Moderna booster dose reported fewer reactions than they did after the second dose of the vaccine. In its study, the CDC found 95% of those who got Moderna for the first round of vaccine shots chose Moderna for the booster dose.

Is it safe to mix and match vaccine and booster brands? Yes

The US Food and Drug Administration has authorized mixing COVID-19 boosters, which in the US means Moderna, Pfizer and Johnson & Johnson. Any adult eligible for a booster can get any of the available brands of coronavirus vaccines. If you initially received Johnson & Johnson and it’s been two months or longer since you received the initial dose, you’ll be able to get the Moderna or Pfizer booster. If you received Moderna or Pfizer for your first two shots, you could pick any authorized vaccine available to you — including J&J — if you qualify and it’s been six months or longer since your second shot.

Is the Moderna COVID-19 booster shot still free?

All booster shots will be free, regardless of immigration or health insurance status. However, depending on where you get your booster shot — for example, at a local pharmacy — you may be asked to log your insurance status. You may be asked to provide your insurance card information, including your name, date of birth and membership number. You will not be charged for your COVID-19 vaccine or booster shot.

Will I need another COVID-19 booster shot?

The CDC updated its guidance to say that in 2022, some immunocompromised people will be able to get a fourth COVID-19 booster shot. It’s unclear if other groups will need to get a fourth dose at this time, but guidance could change in light of the omicron variant.

For more on coronavirus treatments and vaccines, here’s what we know about monoclonal antibody treatments, the new federal vaccine mandates and why some people may not want the shot.

What does the Moderna booster shot do?

A COVID-19 booster shot — whether from Moderna, Pfizer or Johnson & Johnson — tops off your immune response and guards against a breakthrough COVID-19 infection as the vaccine’s effectiveness decreases over time.

Recent studies of the Pfizer and AstraZeneca vaccines show that their effectiveness can begin to wane after six months. Moderna said early data suggests that those who received the Moderna vaccine in 2020 are showing a higher rate of breakthrough COVID-19 infections than those vaccinated this year, suggesting the need for a booster to maintain high levels of protection.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

Technologies

25 years after 9/11, the U.S. starts rolling back travel restrictions, from liquids to gate access

Years after 9/11, the U.S. government is walking back some security screenings as threats and technology evolve.

The Sept. 11, 2001, terror attacks reshaped how we travel, from how we pack our toiletries to what we wear when we fly. Airport checkpoints for almost a quarter century for most travelers have meant shoes off. Limitations on liquids. And no tearful, cinematic gateside farewells or joyful welcomes.

But 25 years later, the U.S. government is starting to ease some of the restrictions, which include measures that were tied to other attacks attempted in the months after 9/11.

Last year, the Department of Homeland Security, which was formed after the attacks, said flyers can leave their shoes on at airports, a major change for travelers going through regular security.

That rule was introduced after Richard Reid, who became known as the “shoe bomber,” tried and failed to ignite explosive material in his shoe on a Paris-to-Miami flight in December 2001.

Rules for liquids are officially unchanged. Those regulations for liquids in carry-ons stem from 2006, when British officials foiled a plot to bring liquid explosives on flights.

New scanners installed at some airport checkpoints allow travelers to leave liquids in their bags before going through screening, though availability varies by airport and checkpoint. Limits on liquid container size remain in effect.

“The technologies today are better than they were a long time ago and some of the technology that’s been deployed is better than it was five years ago,” said Jeff Price, a professor at the Metropolitan State University of Denver’s Department of Aviation and Aerospace Science and an airport management consultant.

Another change since that era is the number of options customers have for airport screening. The Transportation Security Administration, for $76.75 covering five years, offers PreCheck, in which travelers undergo prescreening services and can use expedited screening lanes.

“If you’ve got a few bucks, yeah, you can reduce the amount of screening and jump the line,” Price said. “The other side of that is when you do become a member of PreCheck, you give up a lot more of your personal data to the government, and that’s the trade-off.”

There’s also a private option with Clear, with a shorter identification check line, in exchange for prescreened biometric data.

Gate greetings return

The new changes are going beyond security.

TSA this week launched a free program allowing eligible trusted travelers, including TSA PreCheck members, to apply for access to secure gate areas without a boarding pass.

The program is called “Gateside,” and the agency has rolled it out at 13 U.S. airports, including Dallas Fort Worth International Airport, Los Angeles International Airport, Detroit Metropolitan Wayne County Airport and Salt Lake City International Airport.

The area beyond TSA screening has been heavily restricted since 9/11. In launching the program, the agency said PreCheck members who use the program can “meet family members at their gate, join a friend on a long layover for lunch or dinner, visit airport dining and shopping locations, or greet service members returning from deployment.”

Participants must apply online one to three days in advance and receive approval before entering through security.

Privatization attempt

Some of the tweaks to security have been more rocky.

The TSA late last month scrapped a program it called TSA Gold+ that would provide privatized security at certain airports.

The new head of TSA, David Cummins, who took the top role in early August, said that a new screening partnership program will “replace TSA Gold+ to better harness the role of the private sector in delivering a safer, more secure, and more efficient aviation system.”

TSA didn’t respond to requests for further comment.

Tampa International Airport in Florida had reviewed the program starting in May, in part because it could shield the airport from the impact of government shutdowns, airport Chief Operating Officer John Tiliacos told reporters last month. Those shutdowns left TSA officers without regular paychecks for months, and staffing shortages led to long lines at airports around the country. The chance to add new technology was also a draw.

Tampa decided not to move forward with the program, and TSA announced its replacement shortly after. Tampa’s Tiliacos told reporters last month “we weren’t quite satisfied that we were getting all of the answers to our questions regarding the technology” and that drove the airport’s decision to opt out.

Evolving threats

While some rules travelers have lived with for decades might be fading, the aviation sector is still dealing with changing threats.

“You have AI. You’ve got cybersecurity issues that continue to pop up. Drones are a major issue,” said Keith Jeffries, vice president of aviation security company K2 Security Screening Group, who is retired from the TSA and was the agency’s security director at Los Angeles International Airport. “It’s the role of security and protecting, especially the transportation sector, it’s getting broader, and other technologies are trying to keep up.”

As security technology evolves, so does the energy of potential attackers to overcome whatever obstacle they have and send their message.

Deterrents are important, but Jeffries said: “There is no such thing as the perfect security mousetrap. It doesn’t exist.”

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Technologies

Houthis reportedly advance to key Red Sea island, further threatening crucial oil choke point

The advance raises the threat to shipping near the Bab el-Mandeb Strait, a waterway that connects the Red Sea to the Gulf of Aden to global markets.

The Iran-backed Houthis reportedly advanced to Yemen’s strategic Perim Island on Friday, delivering a major boost to the militant group’s push to take control of one of the world’s most important shipping choke points.

The capture of Perim Island, which was reported by several news agencies, citing multiple Yemeni government sources, comes just one day after the Houthis seized Yemen’s port city of Mokha on the Red Sea coast. CNBC could not independently confirm the report.

The rapid ground offensive is seen as a severe setback to Saudi Arabia and the Yemeni forces it backs and puts Iran and its proxies on course to exercise control over two critically important oil choke points on either side of the Arabian Peninsula: the Bab el-Mandeb Strait and the Strait of Hormuz.

Perim Island is a small and rocky area of land that divides the Bab el-Mandeb Strait, a waterway that connects the Red Sea to the Gulf of Aden and to global markets.

There are concerns that the Houthis’ advance toward the Bab el-Mandeb Strait could have significant ramifications for global trade, particularly if the militant group ratchets up threats or attacks on Red Sea shipping.

The Houthi advance prompted Saudi Crown Prince Mohammed bin Salman to personally press President Donald Trump for U.S. military intervention, MS NOW reported later Friday, according to a person familiar with the conversations.

The crown prince spoke with Trump twice Thursday and urged him to strike the Iranian-backed group as it closed in on the Bab el-Mandeb. Trump declined, saying the U.S. does not plan to widen its regional military campaign to include the Houthis, according to the person, who was granted anonymity because of the sensitive nature of the conversations. Axios first reported the calls.

A senior administration official told CNBC the U.S. remains focused on protecting core national security interests, including freedom of navigation in the Red Sea, “while empowering our regional partners to take the lead in managing and resolving regional security challenges.”

The official added that the U.S. is “in continuous dialogue with Saudi Arabia.”

The capture of Mokha marked a “major blow” to Saudi Arabia as it raises the possibility of the group exerting a tighter grip on the Bab el-Mandeb Strait, according to Hamish Kinnear, principal Middle East and North Africa analyst at risk intelligence company Verisk Maplecroft.

Mokha is situated about 75 kilometers (46 miles) north of the Bab el-Mandeb Strait.

“The Houthis were already threatening Saudi shipping from previous positions, but their capture of Mocha opens up the possibility of further advances towards the Bab el-Mandeb coastline and a tighter grip on the chokepoint,” Kinnear said in a research note.

As the war continues, Kinnear said both Tehran and Washington believe time is on their side, making a new truce unlikely for now.

“Oil and gas prices, and more specifically refined products such as diesel, will continue to tick upwards while that remains the case – even if US convoys and Strait of Hormuz export alternatives cushion the price impact,” Kinnear said.

The strategic importance of the Bab el-Mandeb Strait has grown significantly since the start of the U.S. and Israel’s war against Iran in late February, with the waterway emerging as an alternative route for crude moving toward Asia.

What next for oil prices?

Oil prices traded sharply lower on Friday, but both major benchmarks could still end the week above $100 per barrel for the first time since mid-May.

International benchmark Brent crude

The resilience of the oil market is being tested by a clearer recognition of the mounting threat to regional supply, strategists at ING said, with energy market participants seen repricing both the duration and severity of the conflict.

Even as flows continue through the Strait of Hormuz, ING’s strategists said flows remain well below prewar levels, underlining how fragile the situation has become.

“Saudi energy infrastructure and crude oil exports from the Red Sea are increasingly at risk, with the Houthis in Yemen targeting Saudi Arabia,” ING’s Warren Patterson and Ewa Manthey said in a research note published Friday.

“As the Houthis have taken control of the Red Sea port of Mokha in Yemen, recent events increase the threat to shipping around the Bab al-Mandeb Strait,” they added.

— Luke Fountain contributed to this report.

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Technologies

Wall Street firm believes the AI stock market boom is ‘nearing an end.’ Here’s why

Stretched earnings expectations, extreme concentration and surging equity issuance point to growing bubble risks.

A range of equity market bubble indicators show that while the S & P 500 ‘s rally has further to run this year, its medium-term prospects look poor given how frothy the market has become, according to Capital Economics. “Most indicators suggest the AI equity boom is nearing an end,” Capital Economics’ senior market economist James Reilly said Thursday in a note. Capital has been more bullish than most on the stock market since mid-2023, reflecting a view that AI will be a transformative technology. Its year end-2026 S & P 500 forecast has consistently been above consensus. But the firm has also maintained that the AI-driven rally is a bubble that will eventually burst. To assess and spot a late-stage market bubble, Reilly looks at eight indicators including valuations, earnings, index concentration, equity issuance and foreign interest in U.S. equities. Some of those measures are already at or near levels that preceded previous stock market peaks. The analysis shows that while market variables such as earnings expectations look consistent with a market top, others such as volatility and leverage look slightly less alarming. Earnings stand out as the biggest warning sign. Expectations for S & P 500 earnings growth are around levels seen only at the peak of the dot-com bubble, while long-term EPS growth forecasts have surged to a record high. According to Reilly, the heavy concentration of this expected growth in the tech sector means that any signs of weakness in the tech firms’ earnings will weigh heavily on the index. Other indicators are also flashing warning signs. Index concentration is around dot-com-era extremes, net equity issuance has turned positive and foreign ownership of U.S. stocks is at a record high. Reilly said another wave of IPOs and share sales could be particularly significant, since similar issuance booms have historically coincided with market peaks. “On past form, this suggests that the end of the bubble is just months away, rather than years,” he said. Measures of leverage are not yet alarming compared to other factors, though the analyst warns that they are heading in a “concerning direction.” While volatility metrics look consistent with a mid -stage bubble, Reilly notes that constituent -level volatility isn’t as extreme as it was near the end of the dotcom boom. “While we continue to think that the S & P 500 will rally from around 7,650 now to 8,250 by end-2026 , we ultimately forecast it to fall back to 6,500 by end -2027,” he wrote. Those assumptions would equate to 8% upside this year and a 21% slide in 2027.

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