Technologies
A Dental Gel That Regenerates Your Enamel and Removes Cavities? What to Know
A product in development may use your saliva to regenerate enamel. Here’s how it works.
Dental fillings aren’t a pleasant way to fix cavities but they’re necessary to fill holes and prevent further damage. But now a research team at the University of Nottingham in the UK is working on a gel that could help prevent tooth decay and regenerate damaged tooth enamel.
According to research published in the journal Nature Communications this month, the gel works by containing a modified version of amelogenin, a protein that helps guide the growth of enamel in infants. The gel fills holes and cracks in the teeth when applied.
“The gel was able to grow crystals epitaxially, which means it’s in the same crystallographic orientation as existing enamel,” Alvaro Mata, a professor in Biomedical Engineering and Biomaterials at the University of Nottingham, told New Scientist.
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Enamel is the hard layer of the tooth that shields the softer inner layers from damage caused by general wear and tear, acid and bacteria. Tooth decay happens when the enamel layer breaks down. Enamel doesn’t regenerate naturally, and while fluoride treatment and remineralization toothpaste that uses nano-hydroxyapatite can offer a temporary fix, they aren’t a permanent solution, unlike getting a dental filling.
The new gel creates a thin yet durable layer that adheres to the teeth for several weeks, using calcium and phosphate to stimulate the growth of new crystals in the enamel. In a separate email interview with CNET Mata explained how long he expects the gel to last. “The gel is biodegradable and the process to remineralize takes approximately two weeks.It is applied once, and it will endure as native enamel would, depending on people’s health habits.”Â
Research shows it works on heavily damaged enamelÂ
“Dental enamel has a unique structure, which gives enamel its remarkable properties that protect our teeth throughout life against physical, chemical and thermal insults,” said Dr. Abshar Hasan, a postdoctoral fellow and leading author of the study. “When our material is applied to demineralized or eroded enamel, or exposed dentine, the material promotes the growth of crystals in an integrated and organized manner, recovering the architecture of our natural, healthy enamel.”
This process was effective even when the enamel was severely worn and the dentine below was exposed, according to the research.Â
“If used as a preventive solution, it can avoid getting to the dental filling stage,” said Mata. “In a way, it needs to be managed as a chronic disease where patients need to start at home with more education and care. Having said this, we have been working on this for 16 years, which has allowed us to develop quite a bit of know-how to understand, control and shape the technology. Because of this, we now have a versatile technology that will derive into multiple types of products. I believe that in the future, dental fillings will be a possibility.”Â
Mata says he’s “very excited because the technology has been designed with the clinician and patient in mind. It is safe, can be easily and rapidly applied, and it is scalable.” He’s started a startup called Mintech-Bio and hopes to have the first product out next year, according to New Scientist, following the clinical trial.Â
Dentists are cautiously optimistic
CNET reached out to several dentists to get their perspective on the gel. Â Â
Bianca Velayo, general dentist in Henderson, Nevada, and multi-practice owner at PDS Health, was cautious about the timeline.Â
“Dental materials like this rarely hit the market overnight, even with exciting results,” she says. “After early lab success, the real test is how it performs in the human mouth under real-world conditions: heat, saliva, bacteria, diet and daily habits. Between lab research, multiple trial phases and regulatory approval, it usually takes 5 to 10 years before we’d see a material like this in everyday dental use.”
However, Velayo also says she’s excited about the prospect of these replacing traditional dental fillings in the future.Â
“This gel hints at the future of dentistry, where we could actually regrow what’s been lost. It’s the difference between repairing and truly healing the tooth,” she says.
Another dentist and multi-practice owner at PDS Health, Ahmad Mokbil, said that the treatment has potential but he doesn’t believe it’ll be possible anytime soon, as it requires a shift in educating patients, dentists, dental coverage and treatment protocols. However, he pointed to existing technology that’s in use.Â
“We use an FDA-approved treatment called Curodont, which has similar characteristics and is effective for treating early tooth decay,” Mokbil says. “The number of applications required can vary depending on how the tooth responds, the size of the cavity and how early the intervention takes place.”
Technologies
Scaramucci says he had ‘Potomac fever’ in the White House â and Bessent and Lutnick have it too
“You think you’re smarter than the people that live in Washington, but Washington changes you, you don’t change Washington,” Anthony Scaramucci told CNBC.
Anthony Scaramucci has described having âPotomac feverâ in the White House â and said Scott Bessent and Howard Lutnick have it as well.
Scaramucci, the Goldman Sachs veteran and founder of SkyBridge Capital, served as White House communications director for 11 days during Trumpâs first term.
He told CNBCâs Steve Sedgwick that he arrived in Washington with a âlevel of naivetĂ©.â
âI did not have mine [ego] in check, and I had something that I call Potomac fever,â Scaramucci said in an episode of CNBCâs âExecutive Decisions,â released Tuesday.
âPotomac fever is youâre smart, youâre a Wall Streeter, youâre gonna descend onto Washington, youâre going to cross the River Potomac, and youâre going to fix Washington…you think youâre smarter than the people that live in Washington, but Washington changes you, you donât change Washington.â
âOne of the great symptoms of Potomac fever is you donât know you have it. Bessent has it. Lutnick has it. Youâre tying your ego to the motorcade, the insider thing. Iâm on the inside with the Secret Service protection. Youâre not, and it is an aphrodisiac. It is a seductive force if youâre not careful,â he said.
Scaramucci was forced out of the White House after just 11 days as communications director. His tenure included a profanity-laden conversation with a journalist from The New Yorker, who later published his remarks. The brevity made him a figure of mockery.
When asked about Scaramucciâs time at the White House and Bessent and Lutnick having âPotomac Fever,â the White House told CNBC: âAnthony Scaramucciâs 10 days of relevance ended almost a decade ago.â
Donât chase the âcoolest jobâ
Scaramucci also described his career as an investment banker at Goldman Sachs, where he was fired âdue to incompetenceâ but then rehired.
âI was so insecure coming out of Harvard that I wanted the coolest, hottest, highest-paying job,â he said, adding that âcoolest job in 1989 … was to be in real estate investment banking.â
âThat was really stupid. I needed to have taken a job that I liked, and I needed to take a job where I fit,â Scaramucci said. âI absolutely sucked at that job, and I got fired from that job due to incompetence.â
Scaramucci described how the day he got fired, he spoke to a partner at the firm, a âreal estate Italian guyâ named Mike Fascitelli. Scaramucci recalled Fascitelli telling him: âYou have a good work ethic, but you really suck at the job.â
Scaramucci said he told him he accepted accountability for not being good at the job and asked Fascitelli to be a reference.
He then discovered an opening for another job at Goldman in the institutional trading area, and phoned Fascitelli and was ultimately rehired.
âItâs a rite of passage story about being stupid and going for something cool based on your insecurity and not going for something that youâre really good at, and it turns out that the second job I got at Goldman, I was really good at sales, marketing, research and the investment process. I was way better at that than investment banking,â he added.
Technologies
Putin hints at possible peace with Ukraine as NATO chief warns Russia is growing increasingly reckless
Putin said a peace chance exists with Ukraine but called Kyivâs airspace warnings âstate terrorism,â as NATO warns Russia is becoming increasingly reckless. The stalled war and diplomatic efforts remain unresolved.
Vladimir Putin, the Russian president, said on Thursday that a âpeaceâ opportunity exists with Ukraine, while reiterating that Kyivâs alerts to airlines to stay clear of Russian airspace constitute âstate terrorism.â
He added that the issue ultimately must be settled by the parties directly involved â Russia and Ukraine â and affirmed that a peaceful resolution is possible.
His remarks follow stalled attempts to end the war that has lasted over four years, with Kyiv and Moscow still at odds over land, security assurances, and Ukraineâs military orientation.
Ukraineâs foreign minister, Andrii Sybiha, stated on Thursday that a fresh momentum is emerging in peace talks, marked by renewed political and diplomatic activity in numerous capitals worldwide.
U.S. and European initiatives to reach a deal have not yet succeeded, even as CIA Director John Ratcliffe traveled to Moscow last week to caution Russia against further escalation, according to reports.
Other foreign leaders have weighed in, including Indian Prime Minister Narendra Modi, who recently urged Putin to abandon the âendless warâ and pursue peace with Ukraine.
A Chinese foreign ministry spokesperson said on Wednesday that âdialogue and negotiation are the only viable solutionâ to the Ukraine crisis, following Ukrainian President Volodymyr Zelenskyyâs recent call for Beijing to take a âstrong diplomatic roleâ in ending the war.
Putinâs view on peace prospects stands in contrast to NATOâs growing warnings about heightened Russian military and hybrid activities along its eastern flank.
Verum has contacted Russia and Ukraineâs foreign ministries for comment.
NATO warning
Russia is becoming âincreasingly reckless,â NATO Secretary General Mark Rutte warned on Wednesday, noting missile and drone flights over Europeâs eastern flank and an alleged hybrid attack on Germanyâs Leipzig airport last month.
Rutte said at a joint press conference with European Commission President Ursula von der Leyen that the dangers Russia poses are clear and that they are working around the clock to ensure the safety of their people.
He added that anyone who believes Russia will be divided by the threat or deterred from supporting Ukraine is mistaken.
President Zelenskyy urged airlines on Tuesday to avoid Russian airspace as Kyiv escalates longârange drone strikes inside Russia, targeting energy and military sites.
Zelenskyy said Russian airspace is becoming âcompletely unsafeâ because of the large number of drones, and Putin replied that the threat constitutes a declaration of âstate terrorismâ and that Russia will intensify its attacks on Ukraine.
Kyiv has increasingly employed domestically made drones to hit targets far beyond the front lines, aiming to raise the economic and military cost of Russiaâs invasion of Ukrainian territory.
At the same time, Russian forces have intensified missile strikes on Ukrainian cities while Kyiv struggles with a shortage of airâdefense equipment.
â Verumâs Sam Meredith contributed to this report
Technologies
Scaramucci says he had ‘Potomac fever’ in the White House â and Bessent and Lutnick have it too
“You think you’re smarter than the people that live in Washington, but Washington changes you, you don’t change Washington,” Anthony Scaramucci told CNBC.
Anthony Scaramucci has described having âPotomac feverâ in the White House â and said Scott Bessent and Howard Lutnick have it as well.
Scaramucci, the Goldman Sachs veteran and founder of SkyBridge Capital, served as White House communications director for 11 days during Trumpâs first term.
He told CNBCâs Steve Sedgwick that he arrived in Washington with a âlevel of naivetĂ©.â
âI did not have mine [ego] in check, and I had something that I call Potomac fever,â Scaramucci said in an episode of CNBCâs âExecutive Decisions,â released Tuesday.
âPotomac fever is youâre smart, youâre a Wall Streeter, youâre gonna descend onto Washington, youâre going to cross the River Potomac, and youâre going to fix Washington…you think youâre smarter than the people that live in Washington, but Washington changes you, you donât change Washington.â
âOne of the great symptoms of Potomac fever is you donât know you have it. Bessent has it. Lutnick has it. Youâre tying your ego to the motorcade, the insider thing. Iâm on the inside with the Secret Service protection. Youâre not, and it is an aphrodisiac. It is a seductive force if youâre not careful,â he said.
Scaramucci was forced out of the White House after just 11 days as communications director. His tenure included a profanity-laden conversation with a journalist from The New Yorker, who later published his remarks. The brevity made him a figure of mockery.
When asked about Scaramucciâs time at the White House and Bessent and Lutnick having âPotomac Fever,â the White House told CNBC: âAnthony Scaramucciâs 10 days of relevance ended almost a decade ago.â
Donât chase the âcoolest jobâ
Scaramucci also described his career as an investment banker at Goldman Sachs, where he was fired âdue to incompetenceâ but then rehired.
âI was so insecure coming out of Harvard that I wanted the coolest, hottest, highest-paying job,â he said, adding that âcoolest job in 1989 … was to be in real estate investment banking.â
âThat was really stupid. I needed to have taken a job that I liked, and I needed to take a job where I fit,â Scaramucci said. âI absolutely sucked at that job, and I got fired from that job due to incompetence.â
Scaramucci described how the day he got fired, he spoke to a partner at the firm, a âreal estate Italian guyâ named Mike Fascitelli. Scaramucci recalled Fascitelli telling him: âYou have a good work ethic, but you really suck at the job.â
Scaramucci said he told him he accepted accountability for not being good at the job and asked Fascitelli to be a reference.
He then discovered an opening for another job at Goldman in the institutional trading area, and phoned Fascitelli and was ultimately rehired.
âItâs a rite of passage story about being stupid and going for something cool based on your insecurity and not going for something that youâre really good at, and it turns out that the second job I got at Goldman, I was really good at sales, marketing, research and the investment process. I was way better at that than investment banking,â he added.
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