Technologies

A Dental Gel That Regenerates Your Enamel and Removes Cavities? What to Know

A product in development may use your saliva to regenerate enamel. Here’s how it works.

Dental fillings aren’t a pleasant way to fix cavities but they’re necessary to fill holes and prevent further damage. But now a research team at the University of Nottingham in the UK is working on a gel that could help prevent tooth decay and regenerate damaged tooth enamel.

According to research published in the journal Nature Communications this month, the gel works by containing a modified version of amelogenin, a protein that helps guide the growth of enamel in infants. The gel fills holes and cracks in the teeth when applied.

«The gel was able to grow crystals epitaxially, which means it’s in the same crystallographic orientation as existing enamel,» Alvaro Mata, a professor in Biomedical Engineering and Biomaterials at the University of Nottingham, told New Scientist.

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Enamel is the hard layer of the tooth that shields the softer inner layers from damage caused by general wear and tear, acid and bacteria. Tooth decay happens when the enamel layer breaks down. Enamel doesn’t regenerate naturally, and while fluoride treatment and remineralization toothpaste that uses nano-hydroxyapatite can offer a temporary fix, they aren’t a permanent solution, unlike getting a dental filling.

The new gel creates a thin yet durable layer that adheres to the teeth for several weeks, using calcium and phosphate to stimulate the growth of new crystals in the enamel. In a separate email interview with CNET Mata explained how long he expects the gel to last. «The gel is biodegradable and the process to remineralize takes approximately two weeks.It is applied once, and it will endure as native enamel would, depending on people’s health habits.»

Research shows it works on heavily damaged enamel

«Dental enamel has a unique structure, which gives enamel its remarkable properties that protect our teeth throughout life against physical, chemical and thermal insults,» said Dr. Abshar Hasan, a postdoctoral fellow and leading author of the study. «When our material is applied to demineralized or eroded enamel, or exposed dentine, the material promotes the growth of crystals in an integrated and organized manner, recovering the architecture of our natural, healthy enamel.»

This process was effective even when the enamel was severely worn and the dentine below was exposed, according to the research.

«If used as a preventive solution, it can avoid getting to the dental filling stage,» said Mata. «In a way, it needs to be managed as a chronic disease where patients need to start at home with more education and care. Having said this, we have been working on this for 16 years, which has allowed us to develop quite a bit of know-how to understand, control and shape the technology. Because of this, we now have a versatile technology that will derive into multiple types of products. I believe that in the future, dental fillings will be a possibility.»

Mata says he’s «very excited because the technology has been designed with the clinician and patient in mind. It is safe, can be easily and rapidly applied, and it is scalable.» He’s started a startup called Mintech-Bio and hopes to have the first product out next year, according to New Scientist, following the clinical trial.

Dentists are cautiously optimistic

CNET reached out to several dentists to get their perspective on the gel.

Bianca Velayo, general dentist in Henderson, Nevada, and multi-practice owner at PDS Health, was cautious about the timeline.

«Dental materials like this rarely hit the market overnight, even with exciting results,» she says. «After early lab success, the real test is how it performs in the human mouth under real-world conditions: heat, saliva, bacteria, diet and daily habits. Between lab research, multiple trial phases and regulatory approval, it usually takes 5 to 10 years before we’d see a material like this in everyday dental use.»

However, Velayo also says she’s excited about the prospect of these replacing traditional dental fillings in the future.

«This gel hints at the future of dentistry, where we could actually regrow what’s been lost. It’s the difference between repairing and truly healing the tooth,» she says.

Another dentist and multi-practice owner at PDS Health, Ahmad Mokbil, said that the treatment has potential but he doesn’t believe it’ll be possible anytime soon, as it requires a shift in educating patients, dentists, dental coverage and treatment protocols. However, he pointed to existing technology that’s in use.

«We use an FDA-approved treatment called Curodont, which has similar characteristics and is effective for treating early tooth decay,» Mokbil says. «The number of applications required can vary depending on how the tooth responds, the size of the cavity and how early the intervention takes place.»

Technologies

Stuck in a Coffee Rut? ChatGPT Can Now Plan Your Next Starbucks Order

Don’t be surprised if the chatbot suggests mixing espresso with lemonade.

If you like getting your daily cup of coffee from Starbucks, you’ll now be able to consult with ChatGPT for your next beverage. Starbucks said on Wednesday that a new Starbucks app in ChatGPT, now in beta, will help you figure out your next order based on your mood or craving in the moment.

Although you won’t be able to order your Starbucks coffee directly through the ChatGPT app, it will suggest drinks and menu items you may enjoy, then direct you to the Starbucks app or website to complete your order.

OpenAI has added a host of other apps you can interact with in ChatGPT since announcing the functionality last year. You can do everything from browsing home listings to designing playlists without leaving the chatbot interface.

You’ll be able to use prompts like, «@Starbucks, I want something bright to start my morning,» or upload an image to describe your mood and location. Once the menu suggestion appears in ChatGPT, you can start the order through the chatbot and then complete it in the Starbucks app or online.

Paul Riedel, senior vice president of digital and loyalty at Starbucks, said in a statement that Starbucks noticed customers weren’t always starting off by looking at the menu. «They’re starting with a feeling,» he said. «We wanted to meet customers right in that moment of inspiration and make it easier than ever to find a drink that fits.»

Starbucks said interacting with ChatGPT lets you personalize your order more and discover menu options you never considered before.

(Disclosure: Ziff Davis, CNET’s parent company, in 2025 filed a lawsuit against OpenAI, alleging it infringed Ziff Davis copyrights in training and operating its AI systems.)

When I tried out the new feature, I asked it about the oddest beverage combinations you can get at Starbucks. One interesting combo ChatGPT came up with was espresso with lemonade. The AI described another drink as «basically liquid dessert soup,» if that’s more up your alley.

Technologies

Today’s NYT Connections: Sports Edition Hints and Answers for April 16, #570

Here are hints and the answers for the NYT Connections: Sports Edition puzzle for April 16 No. 570.

Looking for the most recent regular Connections answers? Click here for today’s Connections hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle and Strands puzzles.

Today’s Connections: Sports Edition is a fun one, especially if you enjoy unusual team names. If you’re struggling with today’s puzzle but still want to solve it, read on for hints and the answers.

Connections: Sports Edition is published by The Athletic, the subscription-based sports journalism site owned by The Times. It doesn’t appear in the NYT Games app, but it does in The Athletic’s own app. Or you can play it for free online.

Read more: NYT Connections: Sports Edition Puzzle Comes Out of Beta

Hints for today’s Connections: Sports Edition groups

Here are four hints for the groupings in today’s Connections: Sports Edition puzzle, ranked from the easiest yellow group to the tough (and sometimes bizarre) purple group.

Yellow group hint: Put your glasses on for this.

Green group hint: Hoops home.

Blue group hint: The minors.

Purple group hint: Hidden hoops word.

Answers for today’s Connections: Sports Edition groups

Yellow group: Look at.

Green group: Seen at an NBA court.

Blue group: Double-A baseball teams.

Purple group: Starts with a WNBA team.

Read more: Wordle Cheat Sheet: Here Are the Most Popular Letters Used in English Words

What are today’s Connections: Sports Edition answers?

The yellow words in today’s Connections

The theme is look at. The four answers are observe, spectate, view and watch.

The green words in today’s Connections

The theme is seen at an NBA court. The four answers are benches, half-court logo, scorer’s table and shot clock.

The blue words in today’s Connections

The theme is double-A baseball teams. The four answers are Biscuits, Drillers, Trash Pandas and Wind Surge.

The purple words in today’s Connections

The theme is starts with a WNBA team. The four answers are dreamy, firefly, Skype and sundial.

Technologies

Today’s NYT Mini Crossword Answers for Thursday, April 16

Here are the answers for The New York Times Mini Crossword for April 16.

Looking for the most recent Mini Crossword answer? Click here for today’s Mini Crossword hints, as well as our daily answers and hints for The New York Times Wordle, Strands, Connections and Connections: Sports Edition puzzles.

Need some help with today’s Mini Crossword? It’s pretty simple, but 1-Across is a bit tricky. Read on for all the answers. And if you could use some hints and guidance for daily solving, check out our Mini Crossword tips.

If you’re looking for today’s Wordle, Connections, Connections: Sports Edition and Strands answers, you can visit CNET’s NYT puzzle hints page.

Read more: Tips and Tricks for Solving The New York Times Mini Crossword

Let’s get to those Mini Crossword clues and answers.