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Regen-COV might work before COVID exposure, trial shows: What to know about monoclonal antibodies

Monoclonal antibodies can greatly reduce hospitalization rates in people most at risk of severe COVID-19.
For the most up-to-date news and information about the coronavirus pandemic, visit the WHO and CDC websites.

Monoclonal antibody therapy for COVID-19 is available to people in the US for free who are at higher risk of severe disease in the first few days of their illness, or after they’ve been exposed to the coronavirus. The treatment — lab-made antibodies given to a person that help their immune system stop the infection from spreading — has proven to be a key tool for preventing the coronavirus from turning into severe illness. Preliminary research shows the treatment reduces risk for hospitalization or death by about 70%.

Now, early research is showing the treatment may benefit people much earlier on, before they’ve even been exposed to the coronavirus. Regeneron, one of the drug-makers of the antibody treatments, announced Monday that its drug was 81.6% effective in preventing COVID-19 in a trial period of two to eight months post-treatment. The drug in the study, which is called Regen-COV and was given to participants in a series of four injections, is the same drug as the one currently authorized for use on at-risk people who are in the early stages of COVID-19, and on some people who’ve been exposed to it.

Dr. Myron Cohen, who leads the monoclonal antibody efforts for the National Institutes of Health’s COVID Prevention Network, said in a news release Monday that the results from the drug-maker are «particularly important to those who do not respond to COVID-19 vaccines, including people who are immunocompromised.»

Regen-COV isn’t authorized yet for use in anyone who hasn’t been exposed to or is sick with COVID-19. A few monoclonal antibody therapies, including the one made by Regeneron, have emergency use authorization by the US Food and Drug Administration and should be accessible in doctors’ offices or even some state-run clinics, as seen in states such as Florida and Texas.

Importantly, monoclonal antibodies don’t replace the role of the COVID-19 vaccines in preventing hospitalization and death. According to data from August by the US Centers for Disease Control and Prevention, unvaccinated people were more than 11 times more likely to die from COVID-19 and about 6 times more likely to contract COVID-19 than fully vaccinated people.

A large number of Americans could be eligible for monoclonal antibody treatment if they test positive for COVID-19 (a smaller number would be eligible for the treatment without a positive test, and only a confirmed exposure). For example, everyone age 65 or older, people who are overweight, people with heart, liver, or kidney disease and many more would be eligible for the treatment in the early days of their symptoms.

Here’s what we know now about COVID-19 monoclonal antibodies.

What are monoclonal antibodies, and how do they work?

Monoclonal antibodies are lab-made antibodies that work by binding to bacteria, cancer cells or viruses the way natural antibodies do, stopping them from infecting more cells. The first monoclonal antibody therapy was approved more than 30 years ago and has been used for other illnesses, including the Ebola virus.

Monoclonal antibody treatments for COVID-19 are used before a person gets really sick, usually within 10 days of their first symptom, to prevent hospitalization. The treatment is only approved for people who are at risk of getting extremely sick — those who are age 65 or older and those who have «certain medical conditions,» per the FDA. The same treatment isn’t recommended for people who are already hospitalized with COVID-19.

Monoclonal antibody therapy is also authorized if an at-risk person is exposed to COVID-19, but the definition of «at-risk» in this instance, per the FDA, is a little narrower and reserved for people who are at risk because of a medical condition and unvaccinated or not fully protected by the COVID-19 vaccines because of an immunocompromising condition.

Read more: Pfizer says its COVID-19 antiviral pill reduces risk of serious illness

I tested positive. How do I know if I’m eligible?

If you come down with the coronavirus and are concerned about how the disease will affect you, contacting your doctor to learn your options and the best line of treatment for you is a good idea. But, in general, this specific treatment is reserved for people who are at risk for severe disease. Most people who are infected with COVID-19 will recover at home without medical help.

The people who test positive for COVID-19 and would be eligible or benefit from monoclonal antibody therapy may also be the same people who are eligible for COVID-19 vaccine boosters because of a medical condition. For those who are at risk of severe COVID-19 and would be eligible for monoclonal antibodies if they test positive (if they’re at least 12 years old and weigh at least 88 pounds) the FDA defines «at risk» under the EUA as:

  • All people age 65 and older.
  • People with obesity or those who are overweight (adults with a BMI of more than 25, and children age 12-17 who have a BMI at the 85th percentile or greater).
  • Pregnant people.
  • People with cancer.
  • People with chronic kidney or lung disease.
  • Individuals with cardiovascular disease or hypertension.
  • People with diabetes.
  • People with sickle cell disease.
  • Those living with neurodevelopmental disorders.
  • People who are immunocompromised or taking immunocompromising medication.
  • Those who have a «medical-related technological dependence» (such as a tracheostomy or gastrostomy).

However, the FDA stressed in a fact sheet for Eli Lilly’s treatment (another brand of monoclonal antibodies) that this isn’t a complete list, and other medical conditions or factors including race or ethnicity may also place individuals at higher risk for severe COVID-19. It also pointed to the CDC’s list of «people with certain medical conditions» for other health conditions, which includes things such as depression and Down syndrome as being high-risk conditions.

In sum: If you test positive and feel you are at risk for severe COVID-19 and might qualify for monoclonal antibodies, you should probably speak to a health care professional about them.

Does vaccine status matter?

No, people who test positive for COVID-19 and are eligible for monoclonal antibody therapy because of their age or health condition can be treated regardless of their vaccination status. That is because, while still protective, the vaccines may be less effective at preventing severe disease in some people than others.

However, being unvaccinated might make you eligible for monoclonal antibodies after an exposure to someone with COVID-19. According to the FDA’s authorization of Regen-COV for post-exposure, people eligible for post-exposure treatment must be at risk of severe COVID-19 disease, and either unvaccinated or vaccinated but immunocompromised or taking immunocompromising medications.

I qualify. How do I access the treatment?

Monoclonal antibodies are administered by IV (most commonly) or by injection, so they’re not a prescription you can easily pick up at the pharmacy. According to CNN, the infusion process takes about an hour and patients need to wait a while to be observed for side effects. If you’re at risk for severe COVID-19 and you’ve tested positive or think you have it, ask your doctor where the treatment is available.

If you live in Texas or Florida where there are state-run monoclonal antibody treatment centers, the same eligibility requirements for patients apply. In Florida, this means everyone age 12 and older who is at «high risk for severe illness» can make an appointment and find a monoclonal treatment center at one of the state’s eight locations. In Texas, there are nine antibody infusion centers across the state, but at-risk people need a referral from their doctor.

If you think you qualify for monoclonal antibody treatment but don’t have a health care provider, you can call the Combat COVID Monoclonal Antibodies Call Center at 1-877-332-6585. You can also use this link from the US Department of Health and Human Services antibody therapy finder.

Do monoclonal antibodies interfere with the coronavirus vaccines?

If you were treated with monoclonal antibodies and you haven’t been vaccinated yet, you should wait 90 days after your treatment to make an appointment, according to the CDC. This recommendation is until more is known about how the antibody response from the treatment affects the immune response from getting vaccinated.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

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Technologies

Today’s NYT Mini Crossword Answers for Saturday, July 12

Here are the answers for The New York Times Mini Crossword for July 12.

Looking for the most recent Mini Crossword answer? Click here for today’s Mini Crossword hints, as well as our daily answers and hints for The New York Times Wordle, Strands, Connections and Connections: Sports Edition puzzles.

Need some help with today’s Mini Crossword? It’s one of those long Saturday puzzles, and a few clues are tricky.  Read on for the answers. And if you could use some hints and guidance for daily solving, check out our Mini Crossword tips.

The Mini Crossword is just one of many games in the Times’ games collection. If you’re looking for today’s Wordle, Connections, Connections: Sports Edition and Strands answers, you can visit CNET’s NYT puzzle hints page.

Read more: Tips and Tricks for Solving The New York Times Mini Crossword

Let’s get to those Mini Crossword clues and answers.

Mini across clues and answers

1A clue:  Havana’s home
Answer: CUBA

5A clue: Last word in many bowling alley names
Answer: LANES

6A clue: Lots and lots
Answer: SOMUCH

7A clue: Left-leaning social media site
Answer: BLUESKY

8A clue: Hepburn of «Breakfast at Tiffany’s»
Answer: AUDREY

9A clue: Word after «break» or «banana»
Answer: BREAD

10A clue: Car loan figs.
Answer: APRS

Mini down clues and answers

1D clue: They always shoot their shot
Answer: CAMERAS

2D clue: Brand-new
Answer: UNUSED

3D clue: Woman with «the good hair,» in a famous Beyoncé lyric
Answer: BECKY

4D clue: In need of moisturizer
Answer: ASHY

5D clue: «We can’t hear you back here!»
Answer: LOUDER

6D clue: Drink noisily
Answer: SLURP

7D clue: ___ ghanouj
Answer: BABA

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Technologies

Today’s NYT Connections: Sports Edition Hints and Answers for July 12, #292

Here are hints and the answers for the NYT Connections: Sports Edition puzzle for July 12, No. 292

Looking for the most recent regular Connections answers? Click here for today’s Connections hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle and Strands puzzles.

Today’s Connections: Sports Edition has one of those classic purple categories, where you probably won’t figure it out before you’ve answered all the others. Need help? Read on for hints and the answers.

Connections: Sports Edition is out of beta now, making its debut on Super Bowl Sunday, Feb. 9. That’s a sign that the game has earned enough loyal players that The Athletic, the subscription-based sports journalism site owned by the Times, will continue to publish it. It doesn’t show up in the NYT Games app but now appears in The Athletic’s own app. Or you can continue to play it free online.  

Read more: NYT Connections: Sports Edition Puzzle Comes Out of Beta

Hints for today’s Connections: Sports Edition groups

Here are four hints for the groupings in today’s Connections: Sports Edition puzzle, ranked from the easiest yellow group to the tough (and sometimes bizarre) purple group.

Yellow group hint: Show Me State.

Green group hint: Old Line State.

Blue group hint: Gridiron greats.

Purple group hint: Names begins with a certain creature.

Answers for today’s Connections: Sports Edition groups

Yellow group: Missouri teams.

Green group: Maryland teams.

Blue group: Hall of Fame football coaches.

Purple group: Sports people or terms starting with an animal.

Read more: Wordle Cheat Sheet: Here Are the Most Popular Letters Used in English Words

What are today’s Connections: Sports Edition answers?

The yellow words in today’s Connections

The theme is Missouri teams. The four answers are Blues, Cardinals, Chiefs and Royals.

The green words in today’s Connections

The theme is Maryland teams.  The four answers are Maryland, Navy, Orioles and Ravens.

The blue words in today’s Connections

The theme is Hall of Fame football coaches. The four answers are Levy, Madden, Noll, and Shula.

The purple words in today’s Connections

The theme is sports people or terms starting with an animal. The four answers are batter, Catchings, Cowherd and dogleg.

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Technologies

CNET Daily Tariff Price Tracker: I’m Watching 11 Key Products for Changes, Here’s What’s Happened

The deadline for the start of Trump’s heaviest tariffs has been delayed until next month, leaving consumers stuck with more uncertainty over prices.

For the last three months, tariffs have been a hot topic, leaving consumers and businesses alike worried: Will they hike prices and by how much? It’s a question more relevant than ever this week, as President Trump punts another major deadline down the road and price-slashing Amazon’s Prime Day sales wind down as the week ends.

Amid those worries, I’ve been tracking prices every day for 11 key products likely to be hit by tariff-induced price increases, and the answer I’ve come to so far is this: Not so much, at least not yet. The winding road of tariff inflation still stretches before us into an uncertain future, so the threat of price hikes continues to cloud the horizon.

To date, I’ve seen two noteworthy price increases, one for the Xbox Series X and the other for a popular budget-friendly 4K TV. Some other products — including Apple’s popular AirPods and printer ink — have gone on sale for brief periods. 

CNET Tariff Tracker Index

Above, you can check out a chart with the average price of the 11 products included in this piece over the course of 2025. This will help give you a sense of the overall price changes and fluctuations going on. Further down, you’ll be able to check out charts for each individual product being tracked. 

We’ll be updating this article regularly as prices change. It’s all in the name of helping you make sense of things, so be sure to check back every so often. For more, check out CNET’s guide to whether you should wait to make big purchases or buy them now and get expert tips about how to prepare for a recession.

Methodology

We’re checking prices daily and will update the article and the relevant charts right away to reflect any changes. The following charts show a single bullet point for each month, with the most recent one labeled «Now» and showing the current price. For the past months, we’ve gone with what was the most common price for each item in the given month. 

In most cases, the price stats used in these graphs were pulled from Amazon using the historical price-tracker tool Keepa. For the iPhones, the prices come from Apple’s official materials and are based on the 128-gigabyte base model of the latest offering of the iPhone 16. For the Xbox Series X, the prices were sourced from Best Buy using the tool PriceTracker. If any of these products happen to be on sale at a given time, we’ll be sure to let you know and explain how those price drops differ from longer-term pricing trends that tariffs can cause.

The 11 products we’re tracking

Mostly what we’re tracking in this article are electronic devices and digital items that CNET covers in depth, like iPhones and affordable 4K TVs — along with a typical bag of coffee, a more humble product that isn’t produced in the US to any significant degree. 

The products featured were chosen for a few reasons: Some of them are popular and/or affordable representatives for major consumer tech categories, like smartphones, TVs and game consoles. Others are meant to represent things that consumers might buy more frequently, like printer ink or coffee beans. Some products were chosen over others because they are likely more susceptible to tariffs. Some of these products have been reviewed by CNET or have been featured in some of our best lists.

Below, we’ll get into more about each individual product, and stick around till the end for a rundown of some other products worth noting.

iPhone 16

The iPhone is the most popular smartphone brand in the US, so this was a clear priority for price tracking. The iPhone has also emerged as a major focal point for conversations about tariffs, given its popularity and its susceptibility to import taxes because of its overseas production, largely in China. Trump has reportedly been fixated on the idea that the iPhone can and should be manufactured in the US, an idea that experts have dismissed as a fantasy. Estimates have also suggested that a US-made iPhone would cost as much as $3,500.

Something to note about this graph: The price listed is the one you’ll see if you buy your phone through a major carrier. If you, say, buy direct from Apple or Best Buy without a carrier involved, you’ll be charged an extra $30, so in some places, you might see the list price of the standard iPhone 16 listed as $830.

Apple’s been taking a few steps to protect its prices in the face of these tariffs, flying in bulk shipments of product before they took effect and planning to move production for the US market from China to India. A new Reuters report found that a staggering 97% of iPhones imported from the latter country, March through May, were bound for the US. This latter move drew the anger of Trump again, threatening the company with a 25% tariff if they didn’t move production to the US, an idea CEO Tim Cook has repeatedly shot down in the past. This came after Trump gave a tariff exemption to electronic devices including smartphones, so the future of that move seems in doubt now.

Duracell AA batteries

A lot of the tech products in your home might boast a rechargeable energy source but individual batteries are still an everyday essential and I can tell you from experience that as soon as you forget about them, you’ll be needing to restock. The Duracell AAs we’re tracking are some of the bestselling batteries on Amazon.

Samsung DU7200 TV

Alongside smartphones, televisions are some of the most popular tech products out there, even if they’re an infrequent purchase. This particular product is a popular entry-level 4K TV and was CNET’s pick for best overall budget TV for 2025. Unlike a lot of tech products that have key supply lines in China, Samsung is a South Korean company, so it might have some measure of tariff resistance. 

After spending most of 2025 hovering around $400, this item has now seen some notable upticks on Amazon, most recently sitting around $450. This could potentially be in reaction to Trump’s announcement of 25% tariffs against South Korea this week.

Xbox Series X

Video game software and hardware are a market segment expected to be hit hard by the Trump tariffs. Microsoft’s Xbox is the first console brand to see price hikes — the company cited «market conditions» along with the rising cost of development. Most notably, this included an increase in the price of the flagship Xbox Series X, up from $500 to $600. Numerous Xbox accessories also were affected and the company also said that «certain» games will eventually see a price hike from $70 to $80.

Initially, we were tracking the price of the much more popular Nintendo Switch as a representative of the gaming market. Nintendo has not yet hiked the price of its handheld-console hybrid and stressed that the $450 price tag of the upcoming Switch 2 has not yet been inflated because of tariffs. Sony, meanwhile, has so far only increased prices on its PlayStation hardware in markets outside the US.

AirPods Pro 2

The latest iteration of Apple’s wildly popular true-wireless earbuds are here to represent the headphone market. Much to the chagrin of the audiophiles out there, a quick look at sales charts on Amazon shows you just how much the brand dominates all headphone sales. For most of the year, they’ve hovered around $199, but ahead of Prime Day sales this week they are currently on sale for $149.

HP 962 CMY printer ink

This HP printer ink includes cyan, magenta and yellow all in one product and recently saw its price jump from around $72 — where it stayed for most of 2025 — to $80, which is around its highest price over the last five years. We will be keeping tabs to see if this is a long-term change or a brief uptick. 

This product replaced Overture PLA Filament for 3D printers in this piece, but we’re still tracking that item.

Anker 10,000-mAh, 30-watt power bank

Anker’s accessories are perennially popular in the tech space and the company has already announced that some of its products will get more expensive as a direct result of tariffs. This specific product has also been featured in some of CNET’s lists of the best portable chargers. 

Bose TV speaker

Soundbars have become important purchases, given the often iffy quality of the speakers built into TVs. While not the biggest or the best offering in the space, the Bose TV Speaker is one of the more affordable soundbar options out there, especially hailing from a brand as popular as Bose. You can currently get this model at a healthy discount for Prime Day, down to $200 from $280.

Oral-B Pro 1000 electric toothbrush

They might be a lot more expensive than their traditional counterparts but electric toothbrushes remain a popular choice for consumers because of how well they get the job done. I know my dentist won’t let up on how much I need one. This particular Oral-B offering was CNET’s overall choice for the best electric toothbrush for 2025.

While this product hasn’t seen its price budge one way or another most of the year, there is a $10 coupon listed on Amazon right now.

Lenovo IdeaPad Flex 5i Chromebook

Lenovo is notable among the big laptop manufacturers for being a Chinese company making its products especially susceptible to Trump’s tariffs.

Starbucks Ground Coffee (28-ounce bag)

Coffee is included in this tracker because of its ubiquity —I’m certainly drinking too much of it these days —and because it’s uniquely susceptible to Trump’s tariff agenda. Famously, coffee beans can only be grown within a certain distance from Earth’s equator, a tropical span largely outside the US and known as the «Coffee Belt.» 

Hawaii is the only part of the US that can produce coffee beans, with data from USAFacts showing that 11.5 million pounds were harvested there in the 2022-23 season — little more than a drop in the mug, as the US consumed 282 times that amount of coffee during that period. Making matters worse, Hawaiian coffee production has declined in the past few years.

All that to say: Americans get almost all of their coffee from overseas, making it one of the most likely products to see price hikes from tariffs.

Other products

As mentioned, we occasionally swap out products with different ones that undergo notable price shifts. Here are some things no longer featured above, but that we’re still keeping an eye on:

  • Nintendo Switch: The baseline handheld-console hybrid has held steady around $299 most places — including Amazon — since it released in 2017. Whether that price will be affected by tariffs or the release of the Switch 2 remains to be seen. This product was replaced above with the Xbox Series X.
  • Overture PLA 3D printer filament: This is a popular choice on Amazon for the material needed to run 3D printers. It has held steady around $15 on Amazon all year. This product was replaced above by the HP 962 printer ink.

Here are some products we also wanted to single out that haven’t been featured with a graph yet:

  • Razer Blade 18 (2025), 5070 Ti edition: The latest revision of Razer’s largest gaming laptop saw a $300 price bump recently, with the base model featured an RTX 5070 Ti graphics card now priced at $3,500 ahead of launch, compared to the $3,200 price announced in February. While Razer has stayed mum about the reasoning, it did previously suspend direct sales to the US as Trump’s tariff plans were ramping up in April.
  • Asus ROG Ally X: The premium version of Asus’s Steam Deck competitor handheld gaming PC recently saw a price hike from $799 to $899, coinciding with the announcement of the company’s upcoming Xbox-branded Ally handhelds.
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