Technologies

Regen-COV might work before COVID exposure, trial shows: What to know about monoclonal antibodies

Monoclonal antibodies can greatly reduce hospitalization rates in people most at risk of severe COVID-19.

For the most up-to-date news and information about the coronavirus pandemic, visit the WHO and CDC websites.

Monoclonal antibody therapy for COVID-19 is available to people in the US for free who are at higher risk of severe disease in the first few days of their illness, or after they’ve been exposed to the coronavirus. The treatment — lab-made antibodies given to a person that help their immune system stop the infection from spreading — has proven to be a key tool for preventing the coronavirus from turning into severe illness. Preliminary research shows the treatment reduces risk for hospitalization or death by about 70%.

Now, early research is showing the treatment may benefit people much earlier on, before they’ve even been exposed to the coronavirus. Regeneron, one of the drug-makers of the antibody treatments, announced Monday that its drug was 81.6% effective in preventing COVID-19 in a trial period of two to eight months post-treatment. The drug in the study, which is called Regen-COV and was given to participants in a series of four injections, is the same drug as the one currently authorized for use on at-risk people who are in the early stages of COVID-19, and on some people who’ve been exposed to it.

Dr. Myron Cohen, who leads the monoclonal antibody efforts for the National Institutes of Health’s COVID Prevention Network, said in a news release Monday that the results from the drug-maker are «particularly important to those who do not respond to COVID-19 vaccines, including people who are immunocompromised.»

Regen-COV isn’t authorized yet for use in anyone who hasn’t been exposed to or is sick with COVID-19. A few monoclonal antibody therapies, including the one made by Regeneron, have emergency use authorization by the US Food and Drug Administration and should be accessible in doctors’ offices or even some state-run clinics, as seen in states such as Florida and Texas.

Importantly, monoclonal antibodies don’t replace the role of the COVID-19 vaccines in preventing hospitalization and death. According to data from August by the US Centers for Disease Control and Prevention, unvaccinated people were more than 11 times more likely to die from COVID-19 and about 6 times more likely to contract COVID-19 than fully vaccinated people.

A large number of Americans could be eligible for monoclonal antibody treatment if they test positive for COVID-19 (a smaller number would be eligible for the treatment without a positive test, and only a confirmed exposure). For example, everyone age 65 or older, people who are overweight, people with heart, liver, or kidney disease and many more would be eligible for the treatment in the early days of their symptoms.

Here’s what we know now about COVID-19 monoclonal antibodies.

What are monoclonal antibodies, and how do they work?

Monoclonal antibodies are lab-made antibodies that work by binding to bacteria, cancer cells or viruses the way natural antibodies do, stopping them from infecting more cells. The first monoclonal antibody therapy was approved more than 30 years ago and has been used for other illnesses, including the Ebola virus.

Monoclonal antibody treatments for COVID-19 are used before a person gets really sick, usually within 10 days of their first symptom, to prevent hospitalization. The treatment is only approved for people who are at risk of getting extremely sick — those who are age 65 or older and those who have «certain medical conditions,» per the FDA. The same treatment isn’t recommended for people who are already hospitalized with COVID-19.

Monoclonal antibody therapy is also authorized if an at-risk person is exposed to COVID-19, but the definition of «at-risk» in this instance, per the FDA, is a little narrower and reserved for people who are at risk because of a medical condition and unvaccinated or not fully protected by the COVID-19 vaccines because of an immunocompromising condition.

I tested positive. How do I know if I’m eligible?

If you come down with the coronavirus and are concerned about how the disease will affect you, contacting your doctor to learn your options and the best line of treatment for you is a good idea. But, in general, this specific treatment is reserved for people who are at risk for severe disease. Most people who are infected with COVID-19 will recover at home without medical help.

The people who test positive for COVID-19 and would be eligible or benefit from monoclonal antibody therapy may also be the same people who are eligible for COVID-19 vaccine boosters because of a medical condition. For those who are at risk of severe COVID-19 and would be eligible for monoclonal antibodies if they test positive (if they’re at least 12 years old and weigh at least 88 pounds) the FDA defines «at risk» under the EUA as:

All people age 65 and older.
People with obesity or those who are overweight (adults with a BMI of more than 25, and children age 12-17 who have a BMI at the 85th percentile or greater).
Pregnant people.
People with cancer.
People with chronic kidney or lung disease.
Individuals with cardiovascular disease or hypertension.
People with diabetes.
People with sickle cell disease.
Those living with neurodevelopmental disorders.
People who are immunocompromised or taking immunocompromising medication.
Those who have a «medical-related technological dependence» (such as a tracheostomy or gastrostomy).

However, the FDA stressed in a fact sheet for Eli Lilly’s treatment (another brand of monoclonal antibodies) that this isn’t a complete list, and other medical conditions or factors including race or ethnicity may also place individuals at higher risk for severe COVID-19. It also pointed to the CDC’s list of «people with certain medical conditions» for other health conditions, which includes things such as depression and Down syndrome as being high-risk conditions.

In sum: If you test positive and feel you are at risk for severe COVID-19 and might qualify for monoclonal antibodies, you should probably speak to a health care professional about them.

Does vaccine status matter?

No, people who test positive for COVID-19 and are eligible for monoclonal antibody therapy because of their age or health condition can be treated regardless of their vaccination status. That is because, while still protective, the vaccines may be less effective at preventing severe disease in some people than others.

However, being unvaccinated might make you eligible for monoclonal antibodies after an exposure to someone with COVID-19. According to the FDA’s authorization of Regen-COV for post-exposure, people eligible for post-exposure treatment must be at risk of severe COVID-19 disease, and either unvaccinated or vaccinated but immunocompromised or taking immunocompromising medications.

I qualify. How do I access the treatment?

Monoclonal antibodies are administered by IV (most commonly) or by injection, so they’re not a prescription you can easily pick up at the pharmacy. According to CNN, the infusion process takes about an hour and patients need to wait a while to be observed for side effects. If you’re at risk for severe COVID-19 and you’ve tested positive or think you have it, ask your doctor where the treatment is available.

If you live in Texas or Florida where there are state-run monoclonal antibody treatment centers, the same eligibility requirements for patients apply. In Florida, this means everyone age 12 and older who is at «high risk for severe illness» can make an appointment and find a monoclonal treatment center at one of the state’s eight locations. In Texas, there are nine antibody infusion centers across the state, but at-risk people need a referral from their doctor.

If you think you qualify for monoclonal antibody treatment but don’t have a health care provider, you can call the Combat COVID Monoclonal Antibodies Call Center at 1-877-332-6585. You can also use this link from the US Department of Health and Human Services antibody therapy finder.

Do monoclonal antibodies interfere with the coronavirus vaccines?

If you were treated with monoclonal antibodies and you haven’t been vaccinated yet, you should wait 90 days after your treatment to make an appointment, according to the CDC. This recommendation is until more is known about how the antibody response from the treatment affects the immune response from getting vaccinated.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

Technologies

The Future’s Here: Testing Out Gemini’s Live Camera Mode

Gemini Live’s new camera mode feels like the future when it works. I put it through a stress test with my offbeat collectibles.

«I just spotted your scissors on the table, right next to the green package of pistachios. Do you see them?»

Gemini Live’s chatty new camera feature was right. My scissors were exactly where it said they were, and all I did was pass my camera in front of them at some point during a 15-minute live session of me giving the AI chatbot a tour of my apartment. Google’s been rolling out the new camera mode to all Android phones using the Gemini app for free after a two-week exclusive to Pixel 9 (including the new Pixel 9A) and Galaxy S5 smartphones. So, what exactly is this camera mode and how does it work?

When you start a live session with Gemini, you now how have the option to enable a live camera view, where you can talk to the chatbot and ask it about anything the camera sees. Not only can it identify objects, but you can also ask questions about them — and it works pretty well for the most part. In addition, you can share your screen with Gemini so it can identify things you surface on your phone’s display.

When the new camera feature popped up on my phone, I didn’t hesitate to try it out. In one of my longer tests, I turned it on and started walking through my apartment, asking Gemini what it saw. It identified some fruit, ChapStick and a few other everyday items with no problem. I was wowed when it found my scissors.

That’s because I hadn’t mentioned the scissors at all. Gemini had silently identified them somewhere along the way and then recalled the location with precision. It felt so much like the future, I had to do further testing.

My experiment with Gemini Live’s camera feature was following the lead of the demo that Google did last summer when it first showed off these live video AI capabilities. Gemini reminded the person giving the demo where they’d left their glasses, and it seemed too good to be true. But as I discovered, it was very true indeed.

Gemini Live will recognize a whole lot more than household odds and ends. Google says it’ll help you navigate a crowded train station or figure out the filling of a pastry. It can give you deeper information about artwork, like where an object originated and whether it was a limited edition piece.

It’s more than just a souped-up Google Lens. You talk with it, and it talks to you. I didn’t need to speak to Gemini in any particular way — it was as casual as any conversation. Way better than talking with the old Google Assistant that the company is quickly phasing out.

Google also released a new YouTube video for the April 2025 Pixel Drop showcasing the feature, and there’s now a dedicated page on the Google Store for it.

To get started, you can go live with Gemini, enable the camera and start talking. That’s it.

Gemini Live follows on from Google’s Project Astra, first revealed last year as possibly the company’s biggest «we’re in the future» feature, an experimental next step for generative AI capabilities, beyond your simply typing or even speaking prompts into a chatbot like ChatGPT, Claude or Gemini. It comes as AI companies continue to dramatically increase the skills of AI tools, from video generation to raw processing power. Similar to Gemini Live, there’s Apple’s Visual Intelligence, which the iPhone maker released in a beta form late last year.

My big takeaway is that a feature like Gemini Live has the potential to change how we interact with the world around us, melding our digital and physical worlds together just by holding your camera in front of almost anything.

I put Gemini Live to a real test

The first time I tried it, Gemini was shockingly accurate when I placed a very specific gaming collectible of a stuffed rabbit in my camera’s view. The second time, I showed it to a friend in an art gallery. It identified the tortoise on a cross (don’t ask me) and immediately identified and translated the kanji right next to the tortoise, giving both of us chills and leaving us more than a little creeped out. In a good way, I think.

I got to thinking about how I could stress-test the feature. I tried to screen-record it in action, but it consistently fell apart at that task. And what if I went off the beaten path with it? I’m a huge fan of the horror genre — movies, TV shows, video games — and have countless collectibles, trinkets and what have you. How well would it do with more obscure stuff — like my horror-themed collectibles?

First, let me say that Gemini can be both absolutely incredible and ridiculously frustrating in the same round of questions. I had roughly 11 objects that I was asking Gemini to identify, and it would sometimes get worse the longer the live session ran, so I had to limit sessions to only one or two objects. My guess is that Gemini attempted to use contextual information from previously identified objects to guess new objects put in front of it, which sort of makes sense, but ultimately, neither I nor it benefited from this.

Sometimes, Gemini was just on point, easily landing the correct answers with no fuss or confusion, but this tended to happen with more recent or popular objects. For example, I was surprised when it immediately guessed one of my test objects was not only from Destiny 2, but was a limited edition from a seasonal event from last year.

At other times, Gemini would be way off the mark, and I would need to give it more hints to get into the ballpark of the right answer. And sometimes, it seemed as though Gemini was taking context from my previous live sessions to come up with answers, identifying multiple objects as coming from Silent Hill when they were not. I have a display case dedicated to the game series, so I could see why it would want to dip into that territory quickly.

Gemini can get full-on bugged out at times. On more than one occasion, Gemini misidentified one of the items as a made-up character from the unreleased Silent Hill: f game, clearly merging pieces of different titles into something that never was. The other consistent bug I experienced was when Gemini would produce an incorrect answer, and I would correct it and hint closer at the answer — or straight up give it the answer, only to have it repeat the incorrect answer as if it was a new guess. When that happened, I would close the session and start a new one, which wasn’t always helpful.

One trick I found was that some conversations did better than others. If I scrolled through my Gemini conversation list, tapped an old chat that had gotten a specific item correct, and then went live again from that chat, it would be able to identify the items without issue. While that’s not necessarily surprising, it was interesting to see that some conversations worked better than others, even if you used the same language.

Google didn’t respond to my requests for more information on how Gemini Live works.

I wanted Gemini to successfully answer my sometimes highly specific questions, so I provided plenty of hints to get there. The nudges were often helpful, but not always. Below are a series of objects I tried to get Gemini to identify and provide information about.

Technologies

Today’s Wordle Hints, Answer and Help for April 26, #1407

Here are hints and the answer for today’s Wordle No. 1,407 for April 26. Hint: Fans of a certain musical group will rock out with this puzzle.

Looking for the most recent Wordle answer? Click here for today’s Wordle hints, as well as our daily answers and hints for The New York Times Mini Crossword, Connections, Connections: Sports Edition and Strands puzzles.

Today’s Wordle puzzle isn’t too tough. The letters are fairly common, and fans of a certain rock band might get a kick out of the answer. If you need a new starter word, check out our list of which letters show up the most in English words. If you need hints and the answer, read on.

Today’s Wordle hints

Before we show you today’s Wordle answer, we’ll give you some hints. If you don’t want a spoiler, look away now.

Wordle hint No. 1: Repeats

Today’s Wordle answer has no repeated letters.

Wordle hint No. 2: Vowels

There is one vowel in today’s Wordle answer.

Wordle hint No. 3: Start letter

Today’s Wordle answer begins with the letter C.

Wordle hint No. 4: Rock out

Today’s Wordle answer is the name of a legendary English rock band.

Wordle hint No. 5: Meaning

Today’s Wordle answer can refer to a violent confrontation.

TODAY’S WORDLE ANSWER

Today’s Wordle answer is CLASH.

Yesterday’s Wordle answer

Yesterday’s Wordle answer, April 25, No. 1406 was KNOWN.

Recent Wordle answers

April 21, No. 1402: SPATE

April 22, No. 1403: ARTSY

April 23, No. 1404: OZONE.

April 24, No. 1405: GENIE

What’s the best Wordle starting word?

Don’t be afraid to use our tip sheet ranking all the letters in the alphabet by frequency of uses. In short, you want starter words that lean heavy on E, A and R, and don’t contain Z, J and Q.

Some solid starter words to try:

ADIEU

TRAIN

STARE

NOISE

Technologies

T-Mobile Adds New Top 5G Plans, T-Satellite and New 5-Year Price Locks

The new top unlimited plans, Experience More and Experience Beyond, shave some costs and add data and satellite options.

Just two years after expanding its lineup of cellular plans, T-Mobile this week announced two new plans that replace its Go5G Plus and Go5G Next offerings, refreshed its prepaid Metro line and wrapped them all in a promised five-year pricing guarantee.

To convert more subscribers, the carrier is also offering up to $800 to help customers pay off phone balances when switching from another carrier.

In a briefing with CNET, Jon Friar, president of T-Mobile’s consumer group, explained why the company is revamping and simplifying its array of mobile plans. «The pain point that’s out there over the last couple of years is rising costs all around consumers,» Friar said. «For us to be able to bring more value and even lower prices on [plans like] Experience More versus our former Go5G Plus is a huge win for consumers.»

The new plans went into effect April 23.

With these changes, CNET is already hard at work updating our picks for Best T-Mobile Plans, so check back soon for our recommendations.

More Experiences to define the T-Mobile experience

The top of the new T-Mobile postpaid lineup is two new plans: Experience More and Experience Beyond.

Experience More is the next generation of the Go5G Plus plan, which has unlimited 5G and 4G LTE access and unlimited Premium Data (download speeds up to 418Mbps and upload speeds up to 31Mbps). High-speed hotspot data is bumped up to 60GB from 50GB per month. The monthly price is now $5 lower per line than Go5G Plus.

The Experience More plan also gets free T-Satellite with Starlink service (the new name for T-Mobile’s satellite feature that uses Starlink’s constellation of satellites) through the end of 2025. Although T-Satellite is still officially in beta until July, customers can continue to get free access to the beta starting now. At the start of the new year, the service will cost $10 per month, a $5 drop from T-Mobile’s originally announced pricing. T-Satellite will be open to customers of other carriers for the same pricing beginning in July.

The new top-tier plan, Experience Beyond, also comes in $5 per line cheaper than its predecessor, Go5G Next. It has 250GB of high-speed hotspot data per month, up from 50GB, and more data when you’re traveling outside the US: 30GB in Canada and Mexico (versus 15GB) and 15GB in 215 countries (up from 5GB). T-Satellite service is included in the Experience Beyond plan.

However, one small change to the Experience plans affects that pricing: Taxes and fees, previously included in the Go5G Plus and Go5G Next prices, are now broken out separately. T-Mobile recently announced that one such fee, the Regulatory Programs and Telco Recovery Fee, would increase up to 50 cents per month.

According to T-Mobile, the Experience Beyond rates and features will be «rolling out soon» for customers currently on the Go5G Next plan.

The Essentials plan is staying in the lineup at the same cost of $60 per month for a single line, the same 50GB of Premium Data and unlimited 5G and 4G LTE data. High-speed hotspot data is an optional $10 add-on, as is T-Satellite access, for $15 (both per month).

Also still in the mix is the Essentials Saver plan, an affordable option that has ranked high in CNET’s Best Cellphone Plans recommendations.

Corresponding T-Mobile plans, such as those for military, first responders and people age 55 and older are also getting refreshed with the new lineup.

T-Mobile’s plan shakeup is being driven in part by the current economic climate. Explaining the rationale behind the price reductions and the streamlined number of plans, Mike Katz, president of marketing, innovation and experience at T-Mobile told CNET, «We’re in a weird time right now where prices everywhere are going up and they’ve happened over the last several years. We felt like there was an opportunity to compete with some simplicity, but more importantly, some peace of mind for customers.»

Existing customers who want to switch to one of the new plans can do so at the same rates offered to new customers. Or, if a current plan still works for them, they can continue without changes (although keep in mind that T-Mobile earlier this year increased prices for some legacy plans).

Five years of price stability

It’s nearly impossible to think about prices these days without warily eyeing how tariffs and US economic policy will affect what we pay for things. So it’s not surprising to see carriers implement some cost stability into their plans. For instance, Verizon recently locked prices for three years on their plans.

Now, T-Mobile is building a five-year price guarantee for its T-Mobile and Metro plans. That pricing applies to talk, text and data amounts — not necessarily taxes and other fees that can fluctuate.

Given the uncertain outlook, it seems counterintuitive to lock in a longer rate. When asked about this, Katz said, «We feel like our job is to solve pain points for customers and we feel like this helps with this exact sentiment. It shifts the risk from customers to us. We’ll take the risk so they don’t have to.»

The price hold applies to new customers signing up for the plans as well as current customers switching to one. T-Mobile is offering the same deals and pricing to new and existing subscribers. Also, the five-year deal applies to pricing; it’s not a five-year plan commitment.

More money and options to encourage switchers

The promise of a five-year price guarantee is also intended to lure people from other carriers, particularly AT&T and Verizon. As further incentive, T-Mobile is offering up to $800 per line (distributed via a virtual prepaid Mastercard) to help pay off other carriers’ device contracts. This is a limited-time offer. There are also options to trade in old devices, including locked phones, to get up to four new flagship phones.

Or, if getting out of a contract isn’t an issue, T-Mobile can offer $200 in credit (up to $800 for four lines) to bring an existing number to the network.

Four new Metro prepaid plans

On the prepaid side, T-Mobile is rolling out four new Metro plans, which are also covered by the new five-year price guarantee:

• Metro Starter costs $25 per line per month for a family of four and there is no need to bring an existing number. (The cost is $105 the first month.)

• Metro Starter Plus runs $40 per month for a new phone, unlimited talk, text and 5G data when bringing an existing number. For $65 per month, new customers can get two lines and two new Samsung A15 phones. No autopay is required.

• Metro Flex Unlimited is $30 per line per month with autopay for four lines ($125 the first month) with unlimited talk, text and 5G data.

• Metro Flex Unlimited Plus costs $60 per line per month, then $35 for lines two and three and then lowers the price of the fourth line to $10 per month as more family members are added. Adding a tablet or smartwatch to an existing line costs $5. And streaming video, such as from the included Amazon Prime membership, comes through at HD quality.

See more: If you’re looking for phone plans, you may also be looking for a new cell phone. Here are CNET’s picks.