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How Mark Rober’s DNA Nerf Guns Could Lead to Medical Breakthroughs

Mark Rober explains his yearlong odyssey to break the record for world’s smallest Nerf gun five times, culminating in ones made out of DNA.

When Mark Rober set out to break the record for world’s smallest Nerf gun, he never expected he’d end up making more mini Nerf guns than the total number of actual Nerf guns ever to exist.

In his yearlong mission, Rober ended up breaking the record five times by collaborating with leading experts and employing different engineering techniques. 

tiny-nerf-gun-2

His first few batches of mini Nerf blasters were made possible by drastically simplifying the design of the Nerf gun. «All materials are springs, even glass,» Rober told CNET in an interview. «You just take advantage of that springiness [to] build all the hinges and the springs into one part.»

This one-part design broke the record a few times but eventually reached its limits. At 1,000 times smaller than a standard Nerf gun, about the perfect size for an ant, the mini Nerf guns were still able to fire. They had to be fired with a micro-manipulator, however, since human hands and tweezers would not be precise enough to do the job.

tiny-nerf-gun-1

Beyond that, Rober says a fireable Nerf gun «could be done,» but that the tools required were so expensive as to put it beyond the scope of his video.

Despite no longer being fireable, Rober kept going smaller, in part to protect this particular record from his friend and rival in world-record breaking shenanigans, YouTuber Jimmy Donaldson, aka Mr. Beast. 

Before wrapping up his video, Rober learned of a technique called DNA origami being studied at the Salk Institute and decided to make one last batch of nano Nerf guns.

This technique takes advantage of the fact that DNA naturally binds up when complementary strands are placed in solution together to build out specific shapes. In this case, the right DNA strands placed in the right temperature solution for the right length of time produced trillions of nano Nerf guns. 

nerf-guns-dna

At 100 nanometers in length, they’re smaller than the wavelength of visible light, so «light can’t even bounce off them to get back to your eye.» Rober explained that in order to view their creations, they needed the help of an atomic force microscope.

The technology behind these record-shattering mini Nerf guns could also be applied to medical breakthroughs. Rober explains that DNA origami techniques might be used someday to hack the human body’s biological mechanisms. For example, he says, «if you had 1.2 trillion mini Nerf guns that instead of firing darts were firing something … to kill a bad cell, cancer or fortify a good cell.»

To see our full interview with Rober about his record-breaking nano Nerf guns, check out the video in this article.

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Technologies

Today’s NYT Strands Hints, Answers and Help for Nov. 28 #635

Here are hints and answers for the NYT Strands puzzle for Nov. 28, No. 635.

Looking for the most recent Strands answer? Click here for our daily Strands hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle, Connections and Connections: Sports Edition puzzles.

Today’s NYT Strands puzzle is pretty tricky. If you’re not familiar with certain superstitious beliefs, you might not find all the answers. And some of the answers are difficult to unscramble, so if you need hints and answers, read on.

I go into depth about the rules for Strands in this story. 

If you’re looking for today’s Wordle, Connections and Mini Crossword answers, you can visit CNET’s NYT puzzle hints page.

Read more: NYT Connections Turns 1: These Are the 5 Toughest Puzzles So Far

Hint for today’s Strands puzzle

Today’s Strands theme is: If all else fails…

If that doesn’t help you, here’s a clue: Don’t tell, it won’t come true.

Clue words to unlock in-game hints

Your goal is to find hidden words that fit the puzzle’s theme. If you’re stuck, find any words you can. Every time you find three words of four letters or more, Strands will reveal one of the theme words. These are the words I used to get those hints but any words of four or more letters that you find will work:

  • GLUB, RATS, TARN, DALE, FONT, FOUNT, LASH

Answers for today’s Strands puzzle

These are the answers that tie into the theme. The goal of the puzzle is to find them all, including the spangram, a theme word that reaches from one side of the puzzle to the other. When you have all of them (I originally thought there were always eight but learned that the number can vary), every letter on the board will be used. Here are the nonspangram answers:

  • DANDELION, STAR, COIN, FOUNTAIN, LADYBUG, EYELASH

Today’s Strands spangram

Today’s Strands spangram is MAKEAWISH. To find it, start with the M that’s three letters down on the far right, and wind backwards.

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Technologies

Today’s NYT Connections Hints, Answers and Help for Nov. 28, #901

Here are some hints and the answers for the NYT Connections puzzle for Nov. 28, #901.

Looking for the most recent Connections answers? Click here for today’s Connections hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle, Connections: Sports Edition and Strands puzzles.

Today’s NYT Connections puzzle is kind of tough. If you need help sorting the answers into groups, you’re in the right place. Read on for clues and today’s Connections answers.

The Times now has a Connections Bot, like the one for Wordle. Go there after you play to receive a numeric score and to have the program analyze your answers. Players who are registered with the Times Games section can now nerd out by following their progress, including the number of puzzles completed, win rate, number of times they nabbed a perfect score and their win streak.

Read more: Hints, Tips and Strategies to Help You Win at NYT Connections Every Time

Hints for today’s Connections groups

Here are four hints for the groupings in today’s Connections puzzle, ranked from the easiest yellow group to the tough (and sometimes bizarre) purple group.

Yellow group hint: Appropriate.

Green group hint: I win!

Blue group hint: Musical instrument.

Purple group hint: Time to talk.

Answers for today’s Connections groups

Yellow group: Fitting.

Green group: Achieve victory over.

Blue group: Parts of an electric guitar.

Purple group: Phonetic elements of speech.

Read more: Wordle Cheat Sheet: Here Are the Most Popular Letters Used in English Words

What are today’s Connections answers?

The yellow words in today’s Connections

The theme is fitting. The four answers are fair, just, proper and right.

The green words in today’s Connections

The theme is achieve victory over. The four answers are beat, best, take and worst.

The blue words in today’s Connections

The theme is parts of an electric guitar. The four answers are fret, peg, pickup and string.

The purple words in today’s Connections

The theme is phonetic elements of speech. The four answers are intonation, loudness, rhythm and stress.

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Technologies

Anker’s New MagSafe Car Mount Keeps Your Phone Cool While Charging, and It’s 30% Off for Black Friday

Get wired-like charging speeds and MagSafe compatibility with Anker’s wireless car charging bundle for $62.99.

Black Friday is the best time of the year to upgrade the little essentials that make your everyday tech life more pleasant. I’ve found the perfect deal to amp up the phone charging setup in your car. This Anker MagSafe wireless car charging bundle is 30% off for the holidays, and it gives your iPhone a fast and steady way to power up while you navigate. It delivers up to 25-watt wireless charging speeds and with onboard active cooling, your phone stays comfortable to the touch.

Get it now for $62.99 verses the list price of $89.99.

What sets this charger apart is that its performance and cooling tech is built into a surprisingly compact package. The stand uses an ultra-strong Qi2 magnetic lock to keep your phone secure through bumps and turns. You can even tilt the mount and switch between portrait and landscape modes for navigation without blocking the view. The bundle has everything you need to get started including a 60-watt dual-USB-C charger, an adequately long USB-C cable, and cable organizers for a clean setup. Anker also includes a two-year warranty for peace of mind.

If you are getting your car prepped up for driving to a holiday vacation or just need a faster charging mount for your daily commute, this deal makes a lot of sense. CNET’s experts are also tracking more Black Friday and Cyber Monday picks across Apple products, headphones, and more, so you can score more savings before the sales season wraps up.

MOBILE DEALS OF THE WEEK

Deals are selected by the CNET Group commerce team, and may be unrelated to this article.

Why this deal matters

A high quality charger is a great addition to any car to speedily top up your phone on the go. You will especially want to look out for options from a top-tier brand like Anker for its fast charging speeds and reliability. This Black Friday deal is an excellent opportunity to save big on a staple car accessory. With holiday shopping heating up and tech accessories being one of the most popular categories, we expect the deal to sell out quick. So don’t wait too long before jumping on it.

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