Technologies

Scientists Develop ‘Cellular Glue’ That Could Heal Wounds, Regrow Nerves

One day, these special synthetic molecules could also help mitigate the organ shortage crisis.

Researchers from the University of California, San Francisco announced a fascinating innovation on Monday. They call it «cellular glue» and say it could one day open doors to massive medical achievements, like building organs in a lab for transplantation and reconstructing nerves that’ve been damaged beyond the reach of standard surgical repair.

Basically, the team engineered a set of synthetic molecules that can be manipulated to coax cells within the human body to bond with one another. Together, these molecules constitute the so-called «cellular glue» and act like adhesive molecules naturally found in and around cells that involuntarily dictate the way our tissues, nerves and organs are structured and anchored together.

Only in this case scientists can voluntarily control them.

«The properties of a tissue, like your skin for example, are determined in large part by how the different cells are organized within it,» Adam Stevens, a researcher at UCSF’s Cell Design Institute and first author of a paper in the journal Nature, said in a statement. «We’re devising ways to control this organization of cells, which is central to being able to synthesize tissues with the properties we want them to have.»

Doctors could eventually use the sticky material as a viable mechanism to mend patients’ wounds, regrow nerves otherwise deemed destroyed and potentially even work toward regenerating diseased lungs, livers and other vital organs.

That last bit could lend a hand in alleviating the crisis of donor organs rapidly running out of supply. According to the Health Resources and Services Administration, 17 people in the US die each day while on the waitlist for an organ transplant, yet every 10 minutes, another person is added to that list.

«Our work reveals a flexible molecular adhesion code that determines which cells will interact, and in what way,» Stevens said. «Now that we are starting to understand it, we can harness this code to direct how cells assemble into tissues and organs.»

Ikea cells

Right after babies are born (and even when they’re still in the womb) their cells essentially find it easy to reconnect with one another when a bond is lost. This is primarily because kids are still growing, so their cells are still actively coming together. But as a consequence, that’s also why their scratches and scrapes tend to heal quite quickly.

In other words, think of children’s cell molecules as having lots of clear-cut instructions on how to put themselves together to make tissues, organs and nerves. They’re like sentient little pieces of Ikea furniture with the store’s building booklet in hand.

As people get older, however, those biological Ikea instructions get put in the attic, the team explains. That’s because, for the most part, the body is pretty solidified — and this is sometimes a problem. For instance, when someone’s liver gets really damaged, their liver cell molecules may need to refer back to those Ikea instructions but can’t find them.

But that’s where «cellular glue» molecules come in. These rescuers can essentially be primed with those Ikea instructions before being sent into the body, so their blueprint is fresh. Scientists can load them up with information on which cell molecules to bond with and even how strongly to bond with them.

Then, these glue molecules can guide relevant cells toward one another, helping along the healing and regeneration processes.

«In a solid organ, like a lung or a liver, many of the cells will be bonded quite tightly,» explains a UCSF description of the new invention. «But in the immune system, weaker bonds enable the cells to flow through blood vessels or crawl between the tightly bound cells of skin or organ tissues to reach a pathogen or a wound.»

To make this kind of customization possible, the researchers added two important components to their cellular glue. First, part of the molecule acts as a receptor. It remains on the outside of the cell and determines which other cells the molecule is allowed to interact with. Second, there’s the bond-strength-tuner. This section exists within the cell. Mix and match those two traits and, the team says, you can create an array of cell adhesion molecules prepped to bond in various ways.

«We were able to engineer cells in a manner that allows us to control which cells they interact with, and also to control the nature of that interaction,» Wendell Lim, director of UCSF’s Cell Design Institute and senior author of the paper, said in a statement.

In fact, the team says the range of potential molecules is wide enough that they could inform the academic stage of medical studies, too. Researchers could make mock tissues, for example, to deepen understanding of the human body as a whole.

Or as Stevens put it, «These tools could be really transformative.»

Technologies

Worldwide Financial Services Directory: BitcoinPay Trade Joins Financial1000

Exciting news for BitcoinPay Trade as the company is officially listed on Financial1000, a respected platform that connects individuals with a wide range of businesses and professionals in the financial sector. This new development marks an important milestone for BitcoinPay Trade, as it continues to expand its reach and offer its services to a growing global audience.

Financial1000 is a trusted directory that brings together financial service providers from around the world, offering users the opportunity to explore various businesses and professionals within the financial industry. BitcoinPay Trade’s inclusion on this platform ensures the company’s place in the rapidly growing digital finance landscape.

Visitors are invited to explore BitcoinPay Trade’s profile on Financial1000 to discover the services offered and stay up-to-date with the latest news and developments. The company’s page can be accessed here: BitcoinPay Trade on Financial1000.

With this new addition, BitcoinPay Trade looks forward to building new connections and strengthening its presence in the financial services industry, continuing to provide innovative solutions to clients worldwide.

Technologies

Verum Coin Now Available on HB Wallet

Verum Coin (VERUM) continues to expand its ecosystem and strengthen its position in the global cryptocurrency market. We are delighted to announce that Verum Coin is now available on HB Wallet — a modern, secure, and user-friendly solution for managing digital assets.

HB Wallet provides users with a high level of protection, an intuitive interface, and the ability to execute fast transactions. Now, Verum Coin holders can easily store, send, and receive their assets, taking advantage of this innovative wallet. The integration with HB Wallet opens new horizons for crypto enthusiasts, offering even greater flexibility and convenience in managing their investments.

This news underscores Verum Coin’s commitment to continuous improvement and the expansion of services aimed at providing the most secure and comfortable experience for users around the world.

About Verum Coin

Verum Coin is an innovative cryptocurrency focused on delivering advanced solutions for digital asset management in today’s financial landscape. By continually expanding its ecosystem, Verum Coin makes cryptocurrency transactions more accessible and convenient for users worldwide.

Technologies

Verum Messenger Celebrates Its 4th Anniversary: A Journey Towards Security, Innovation, and User Trust

Today, Verum Messenger, one of the leading messengers on the market, celebrates its 4th anniversary. Over the years, the app has become a symbol of security, privacy, and innovation in the world of digital communication, and continues to evolve confidently, introducing new features and improving the quality of service.

When Verum Messenger was launched in 2021, its goal was clear — to create a communication platform that puts data security first. Four years later, this messenger has proven that its approach works. The app has not only successfully implemented end-to-end encryption to protect messages but has also offered unique features such as the ability to block screenshots and screen recordings, the built-in Verum VPN service that ensures online anonymity and security, and one-click information clearing within the messenger.

Achievements and Innovations

Over the past four years, Verum Messenger has significantly expanded its capabilities and established itself as one of the most secure messengers. One of the key milestones was the integration of Verum E-SIM, a feature that allows users to connect to mobile internet without the need for a physical SIM card. This was a breakthrough for travelers who value flexibility and anonymity without being dependent on mobile carriers and roaming.

But the most important achievement was the introduction of Verum AI — a generative artificial intelligence developed in-house. This chatbot, integrated into the messenger, provides users with a unique opportunity to interact with an intelligent assistant capable of not only answering questions but also giving recommendations and solving everyday tasks. This feature is one of the first among messengers to offer its own neural network that continually adapts to users’ needs and improves its functionality.

Commitment to Data Security

It is important to note that data security remains the top priority for Verum Messenger. The company has always been dedicated to protecting privacy. In recent years, the app has introduced several improvements aimed at safeguarding users from data breaches and unauthorized access.

Moreover, Verum Messenger continues to develop and enhance its privacy settings, giving users control over who can view their information and who can contact them.

The Future of Verum Messenger

Now, four years after its launch, Verum Messenger is not stopping at its achievements. The company is actively working on new innovations and improvements that will help the messenger remain at the forefront of technology.

“Our users and their right to privacy and security have always been and will remain our top priority. We will continue to work to ensure that Verum Messenger remains the safest and most convenient tool for communication, considering new challenges and technologies,” the development team shares its plans.