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Scientists Develop ‘Cellular Glue’ That Could Heal Wounds, Regrow Nerves

One day, these special synthetic molecules could also help mitigate the organ shortage crisis.

Researchers from the University of California, San Francisco announced a fascinating innovation on Monday. They call it «cellular glue» and say it could one day open doors to massive medical achievements, like building organs in a lab for transplantation and reconstructing nerves that’ve been damaged beyond the reach of standard surgical repair.

Basically, the team engineered a set of synthetic molecules that can be manipulated to coax cells within the human body to bond with one another. Together, these molecules constitute the so-called «cellular glue» and act like adhesive molecules naturally found in and around cells that involuntarily dictate the way our tissues, nerves and organs are structured and anchored together.

Only in this case scientists can voluntarily control them.

«The properties of a tissue, like your skin for example, are determined in large part by how the different cells are organized within it,» Adam Stevens, a researcher at UCSF’s Cell Design Institute and first author of a paper in the journal Nature, said in a statement. «We’re devising ways to control this organization of cells, which is central to being able to synthesize tissues with the properties we want them to have.»

Doctors could eventually use the sticky material as a viable mechanism to mend patients’ wounds, regrow nerves otherwise deemed destroyed and potentially even work toward regenerating diseased lungs, livers and other vital organs.

That last bit could lend a hand in alleviating the crisis of donor organs rapidly running out of supply. According to the Health Resources and Services Administration, 17 people in the US die each day while on the waitlist for an organ transplant, yet every 10 minutes, another person is added to that list.

«Our work reveals a flexible molecular adhesion code that determines which cells will interact, and in what way,» Stevens said. «Now that we are starting to understand it, we can harness this code to direct how cells assemble into tissues and organs.»

Ikea cells

Right after babies are born (and even when they’re still in the womb) their cells essentially find it easy to reconnect with one another when a bond is lost. This is primarily because kids are still growing, so their cells are still actively coming together. But as a consequence, that’s also why their scratches and scrapes tend to heal quite quickly.

In other words, think of children’s cell molecules as having lots of clear-cut instructions on how to put themselves together to make tissues, organs and nerves. They’re like sentient little pieces of Ikea furniture with the store’s building booklet in hand.

As people get older, however, those biological Ikea instructions get put in the attic, the team explains. That’s because, for the most part, the body is pretty solidified — and this is sometimes a problem. For instance, when someone’s liver gets really damaged, their liver cell molecules may need to refer back to those Ikea instructions but can’t find them.

But that’s where «cellular glue» molecules come in. These rescuers can essentially be primed with those Ikea instructions before being sent into the body, so their blueprint is fresh. Scientists can load them up with information on which cell molecules to bond with and even how strongly to bond with them.

Then, these glue molecules can guide relevant cells toward one another, helping along the healing and regeneration processes.

«In a solid organ, like a lung or a liver, many of the cells will be bonded quite tightly,» explains a UCSF description of the new invention. «But in the immune system, weaker bonds enable the cells to flow through blood vessels or crawl between the tightly bound cells of skin or organ tissues to reach a pathogen or a wound.»

To make this kind of customization possible, the researchers added two important components to their cellular glue. First, part of the molecule acts as a receptor. It remains on the outside of the cell and determines which other cells the molecule is allowed to interact with. Second, there’s the bond-strength-tuner. This section exists within the cell. Mix and match those two traits and, the team says, you can create an array of cell adhesion molecules prepped to bond in various ways.

«We were able to engineer cells in a manner that allows us to control which cells they interact with, and also to control the nature of that interaction,» Wendell Lim, director of UCSF’s Cell Design Institute and senior author of the paper, said in a statement.

In fact, the team says the range of potential molecules is wide enough that they could inform the academic stage of medical studies, too. Researchers could make mock tissues, for example, to deepen understanding of the human body as a whole.

Or as Stevens put it, «These tools could be really transformative.»

Technologies

Call-Recording App Neon Disappeared Abruptly. Now It’s Back for Another Try

The app stirred privacy and security questions offering to pay people for recordings of their phone calls to train AI models. A security flaw didn’t help.

In September, the Neon app briefly became a sensation on app download charts by promising to pay users for recording and sharing their phone calls. Then it abruptly went offline amid controversy over its security practices, privacy protections and payment structure. 

More than a month later, Neon has returned to the iOS App Store and the Google Play Store, and the New York-based companyfollowed up a few days later with a new payout formula. Its founder, Alex Kiam, says the security issues have been resolved, but without offering much detail.

How far the company has progressed remains unclear. An email from Kiam to users on Thursday was sprinkled with phrasing like «while we prepare this new version of the app» and «once the new version of the app launches.»

In our own tests, we were unable to get the new version of Neon to work on iOS. A screen that asks to verify a phone number for signup didn’t trigger a phone call as expected.   

Neon sells the recordings of user calls to companies training AI models, which are hungry for real-world input, such as how people speak conversationally. The company says it anonymizes call information. 

Privacy experts CNET spoke to warned against using the app in its previous incarnation due to concerns over call consent laws, and also noted that AI could infer user information or identities even if call data is anonymized.   


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What’s changed with the Neon app?

Shortly after Neon soared on the app store charts, the news site TechCrunch discovered a security flaw that allowed people to access calls from other users, including transcripts and metadata about the calls. After the app went dark, Kiam said that the company would address the issue and that the app would return with a bonus for users. 

At that time, users of the app could call anyone and get paid. According to the company, only the app user’s side of the call was sold, since in some states, it’s not legal to record a conversation without permission. 

The new version is attempting to circumvent these state issues with a new app-to-app setup: Both parties to the call must have the Neon app installed, essentially making it an opt-in service. Only calls from one Neon user to another Neon user are paid, meaning both people on the call have signed up with the company.

In his email on Thursday, Kiam list details of the updated formula for payments. It starts out with pay to users of 20 cents per minute for the first 20 minutes of call time per day, to a maximum of $4 a day. The plan also describes payments for referrals to the app, up to $50 a day from referral earnings — as long as users «don’t try to game the system with fake calls» — with the potential for a higher daily maximum for users «who have referred a lot of people.»

That is, earning potential is based largely on users getting other people to sign up and use the app.

Users posting comments on the Google Play Store have given the company low ratings, complaining that referral rates have dropped to as low as $1 and that call payment rates may be as low as 5 cents per minute. The app currently has a rating of 2.2 stars out of 5 on the Google Play Store and 2.7 stars out of 5 on the App Store for iOS.

Security concerns with Neon

When Neon went offline, it was with the expectation that the company would fix the vulnerability that could have allowed someone to access calls from other users. 

Kiam told CNET via email that the company «engaged with» three cybersecurity firms after the security hole was found and engaged a contractor to perform a code review to address security concerns. He said that Neon later hired that contractor as its chief technology officer. He didn’t name the contractor, but said the person is «the former CTO of a reasonably large tech company who has 20 years of experience building secure platforms.» 

Neon addressed the underlying issue TechCrunch found, Kiam said, and didn’t discover any evidence of «malicious actors» accessing its database. He didn’t elaborate on how the company addressed that issue.

The delay in bringing Neon back to iOS was not intentional, he said. «I wanted to bring Neon back quickly, but it was important that we did this right.» 

Neon’s updated terms of service

As part of its relaunch, Neon has waived the $30-per-day limit on pending payouts. Kiam said the company plans «a future pleasant surprise» for those who were already using the app.

According to the updated terms of service from Nov. 3, those who sign up for the app agree that Neon can «sell and offer for sale» call recordings «for the purpose of developing, training, testing, and improving machine learning models, artificial intelligence tools and systems, and related technologies.»

There is still concerning language regarding Neon’s rights and licenses that grant the company the authority to publicly display, reproduce and distribute call recordings «in any media formats and through any media channels.»

The appeal of earning a few extra bucks for very little effort is understandable, especially when many people are worried about money amid tech industry layoffs, the US government shutdown and the suspension of services like the SNAP food assistance program.  

Still, security concerns, the ethics of turning over personal conversations to AI companies, the lack of clarity about payments and complaints in user reviews should give users pause.

In an interview with CNET in early October, Kiam said his company was overwhelmed by the sudden popularity of Neon, but not completely surprised.

«I expected things to grow pretty quickly because … we’re getting people money for something that they would do anyway,» Kiam said. «We felt confident that there was real demand for something like this.»

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Technologies

Upgrade Your Mobile Gaming Experience With This Best-Ever Price on the GameSir G8 Plus

At just $72, this deal saves you $28 on a great controller for gaming on the go.

Mobile gaming has come in leaps and bounds in recent years, and some of the best games can be found on your phone. But touchscreens aren’t suited to all kinds of games, and that’s why a controller is a good pickup for any mobile gamer. The GameSir G8 Plus works with phones and tablets, and right now it’s yours for its lowest-ever price of just $72. That’s down $28 from its original price and about 10% off the price we’ve been seeing lately.

This deal doesn’t ask you to enter any codes or clip any coupons, but you should be aware of its limited-time label. Stocks could run dry at any time, so make sure to order your new controller soon to avoid missing out.

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The GameSir G8 Plus supports both Android and iOS, and connects to your device using Bluetooth. You place your phone or tablet into the controller itself, creating a Nintendo Switch-like experience.

The controller itself has Hall Effect joysticks to avoid age-old issues like stick drift, and the six-axis motion-sensing technology is useful for games that support motion controls. You can even connect this controller to your PC via a USB-C cable and play there, too.

Our reviewer, Jason Cockerham, thinks this controller is worth grabbing if you don’t mind dealing with its software. He goes into more detail in his full review, but notes that, «If you don’t care much about the lackluster app, then the G8 Plus really is a solid controller. It feels great, responds well, and has respectable battery life.» He also added that, «It’s a great controller, even for $100.» And now that it’s down to $72, it’s a much better value. 


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Why this deal matters

Sometimes it can be difficult to find time to fire up a console or PC, but that doesn’t have to mean you can’t play. Mobile gaming is a great way to game when you might otherwise not be able to, and this controller gives you a familiar gaming feel on the go — and at an excellent price, too.

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Technologies

The Top-Rated Motorola 2025 G Stylus Just Hit $300, a New Low for the Stylus-First Android

This 8GB/256GB unlocked model is 25% off at Amazon — with a built-in stylus, fast charging and Android 15.

Motorola’s G Stylus line has always leaned into utility, and the 2025 version adds a few thoughtful upgrades without pushing the price too far. It’s one of the few phones in its class with a built-in stylus, and it now supports Android 15, AI features and faster charging. If you’re looking for a mid-range phone that doesn’t feel stripped down, this one’s worth a look.

Amazon has dropped the 2025 Moto G Stylus to $300, a $100 discount off its $400 list price — that’s 25% off. Grab the deal while it lasts. It’s the lowest price we’ve seen for this configuration, which includes 8GB of RAM and 256GB of storage. For comparison, the 2024 model is currently available for $200 at Best Buy; however, it lacks the newer chip and faster charging capabilities.

The 2025 G Stylus features a 6.7-inch pOLED display with a 120Hz refresh rate and Dolby Atmos support. A Snapdragon processor powers it, runs Android 15 and includes a 50 MP primary camera with AI enhancements. The stylus is built in, and the phone supports sketching, note-taking and photo markup without requiring a separate accessory.

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Charging is fast — Motorola says you can get “power for the day” in just 15 minutes. However, the 68W TurboPower charger is sold separately. The phone also includes IP68 water resistance, a vegan leather finish and MIL-STD-810H durability testing.

In CNET’s hands-on coverage, the phone was praised for bringing AI features to a lower price tier. It’s also been called “the fastest charging phone under $400” — a rare distinction in this category.

For more picks, check out our best Android phones and top budget phone deals.

Why this deal matters

Stylus-equipped phones are rare in the midrange category. The 2025 Moto G Stylus adds fast charging, AI features and a premium display — all for $300. With 256GB of storage and Android 15, it’s a well-rounded option for phone users who want flexibility without overspending.

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