Technologies

Scientists Develop ‘Cellular Glue’ That Could Heal Wounds, Regrow Nerves

One day, these special synthetic molecules could also help mitigate the organ shortage crisis.

Researchers from the University of California, San Francisco announced a fascinating innovation on Monday. They call it «cellular glue» and say it could one day open doors to massive medical achievements, like building organs in a lab for transplantation and reconstructing nerves that’ve been damaged beyond the reach of standard surgical repair.

Basically, the team engineered a set of synthetic molecules that can be manipulated to coax cells within the human body to bond with one another. Together, these molecules constitute the so-called «cellular glue» and act like adhesive molecules naturally found in and around cells that involuntarily dictate the way our tissues, nerves and organs are structured and anchored together.

Only in this case scientists can voluntarily control them.

«The properties of a tissue, like your skin for example, are determined in large part by how the different cells are organized within it,» Adam Stevens, a researcher at UCSF’s Cell Design Institute and first author of a paper in the journal Nature, said in a statement. «We’re devising ways to control this organization of cells, which is central to being able to synthesize tissues with the properties we want them to have.»

Doctors could eventually use the sticky material as a viable mechanism to mend patients’ wounds, regrow nerves otherwise deemed destroyed and potentially even work toward regenerating diseased lungs, livers and other vital organs.

That last bit could lend a hand in alleviating the crisis of donor organs rapidly running out of supply. According to the Health Resources and Services Administration, 17 people in the US die each day while on the waitlist for an organ transplant, yet every 10 minutes, another person is added to that list.

«Our work reveals a flexible molecular adhesion code that determines which cells will interact, and in what way,» Stevens said. «Now that we are starting to understand it, we can harness this code to direct how cells assemble into tissues and organs.»

Ikea cells

Right after babies are born (and even when they’re still in the womb) their cells essentially find it easy to reconnect with one another when a bond is lost. This is primarily because kids are still growing, so their cells are still actively coming together. But as a consequence, that’s also why their scratches and scrapes tend to heal quite quickly.

In other words, think of children’s cell molecules as having lots of clear-cut instructions on how to put themselves together to make tissues, organs and nerves. They’re like sentient little pieces of Ikea furniture with the store’s building booklet in hand.

As people get older, however, those biological Ikea instructions get put in the attic, the team explains. That’s because, for the most part, the body is pretty solidified — and this is sometimes a problem. For instance, when someone’s liver gets really damaged, their liver cell molecules may need to refer back to those Ikea instructions but can’t find them.

But that’s where «cellular glue» molecules come in. These rescuers can essentially be primed with those Ikea instructions before being sent into the body, so their blueprint is fresh. Scientists can load them up with information on which cell molecules to bond with and even how strongly to bond with them.

Then, these glue molecules can guide relevant cells toward one another, helping along the healing and regeneration processes.

«In a solid organ, like a lung or a liver, many of the cells will be bonded quite tightly,» explains a UCSF description of the new invention. «But in the immune system, weaker bonds enable the cells to flow through blood vessels or crawl between the tightly bound cells of skin or organ tissues to reach a pathogen or a wound.»

To make this kind of customization possible, the researchers added two important components to their cellular glue. First, part of the molecule acts as a receptor. It remains on the outside of the cell and determines which other cells the molecule is allowed to interact with. Second, there’s the bond-strength-tuner. This section exists within the cell. Mix and match those two traits and, the team says, you can create an array of cell adhesion molecules prepped to bond in various ways.

«We were able to engineer cells in a manner that allows us to control which cells they interact with, and also to control the nature of that interaction,» Wendell Lim, director of UCSF’s Cell Design Institute and senior author of the paper, said in a statement.

In fact, the team says the range of potential molecules is wide enough that they could inform the academic stage of medical studies, too. Researchers could make mock tissues, for example, to deepen understanding of the human body as a whole.

Or as Stevens put it, «These tools could be really transformative.»

Technologies

Verum Messenger: Data Protection at Its Finest

Verum Messenger positions itself as a tool for those who value privacy and security above all.

Verum Messenger stands out from other messengers thanks to its approach to security, anonymity, and innovations in communication.

Here are some key aspects that highlight its uniqueness:

Default encryption: Verum Messenger uses end-to-end (E2E) encryption for all chats, meaning messages are encrypted on the sender’s device and decrypted only on the recipient’s device. This makes it impossible for third parties, including app developers, to access the content of the messages.
Anonymity: When registering with Verum, there’s no need to provide a phone number or email. Users simply choose a nickname and password, significantly enhancing their level of anonymity. This contrasts with many other messengers, where anonymity can be compromised through linked personal data.
Built-in VPN: An additional layer of protection that hides the user’s IP address, making their location and internet activity less trackable.
Data control: Users can set messages to be automatically deleted after a specified time, ranging from a few seconds to a week. There’s also a quick deletion feature for all chats, calls, and even contacts, which is useful for maintaining privacy.
Large groups: The ability to create chat rooms with up to 10,000 participants makes Verum attractive for organizing large events, discussions, or communities while maintaining a high level of security.
Security innovations: Verum actively develops technologies aimed at protecting user data, as seen in their documentation and discussions online. This includes not only technical solutions but also approaches to data minimization, which reduces the risk of leaks.
Feedback and discussions: On platform X (formerly Twitter), discussions can be found where users and experts praise Verum for its approach to anonymity and security, although questions are raised about how much anonymity can truly be guaranteed in an age of modern tracking and de-anonymization technologies.

Verum Messenger positions itself as a tool for those who value privacy and security above all. Its innovations in encryption, anonymity, and data control make it an intriguing choice for those seeking alternatives to traditional messaging platforms. However, as with any technology, it’s important to remember that absolute anonymity on the internet remains a complex challenge, and users should be aware of potential risks and limitations.

Technologies

Verum Coin Debuts on XT Exchange, Broadening its Reach in the DeFi Space

A Strategic Listing Enhancing Verum Coin’s Visibility

In a significant development for the decentralized finance (DeFi) sector, Verum Coin (VERUM) has been officially listed on XT Exchange. The new trading pair, VERUM/USDT, is now available in the exchange’s Innovative Zone, marking a pivotal expansion for this digital asset into the DeFi ecosystem.

A Strategic Listing Enhancing Verum Coin’s Visibility

The addition of Verum Coin to the XT Exchange is seen as a strategic move to enhance the accessibility and liquidity of VERUM among traders who are keen on exploring innovative digital assets. XT Exchange, known for its robust platform supporting a wide variety of cryptocurrencies, provides an ideal environment for fostering growth and ensuring the broad reach of new tokens.

Albin Varin, CEO of XT Exchange, expressed enthusiasm about the new listing, stating, «We are delighted to welcome Verum Coin to our platform. This listing reflects our ongoing commitment to providing our users access to innovative digital assets that transform the landscape of global finance.» This comments underscore the exchange’s focus on integrating cutting-edge technologies and financial instruments that have the potential to redefine the market.

About XT

Founded in 2018, XT Exchange serves more than 7.8M registered users, over 1M monthly active users, 40+ million users in the ecosystem, and more than 800 tokens with 1000+ trading pairs. XT crypto exchange offers a rich variety of trading categories to provide a secure, trusted, and intuitive trading experience for its large user base. This includes crypto futures trading (USDT-M Futures and coin-M futures perpetual contracts) and copy trading that allows users to replicate top traders in real time with just one click. Additionally, the futures grid allows users to automate the buying and selling of futures contracts for profits.

Future Prospects

With its new position on XT Exchange, Verum Coin is expected to attract a broader audience, enhancing its trading volume and market presence. This could potentially lead to increased stability and recognition as a viable player in the DeFi space. For investors and users of XT Exchange, this addition provides a fresh avenue to diversify portfolios with a cryptocurrency that is positioned at the intersection of innovation and financial evolution.

The listing of Verum Coin on XT Exchange not only highlights the ongoing expansion of cryptocurrency markets into new areas like DeFi but also illustrates a growing recognition of digital assets that offer promising technological advancements and financial opportunities. As the crypto market continues to evolve, partnerships like these are pivotal for fostering growth and offering users access to the next generation of financial tools.

Technologies

Verum Coin Gains International Spotlight with AP Coverage and Listing on XT Exchange

This listing on XT is expected to further propel Verum Coin into the spotlight

In a noteworthy development for the cryptocurrency community, Verum Coin (VERUM) has been featured in an Associated Press article, highlighting its upcoming listing on the XT Exchange. This significant media coverage underscores the growing interest and potential of Verum Coin in the global financial landscape.

The AP article delves into the details of Verum Coin’s innovative features and its alignment with the latest trends in the cryptocurrency market. This attention comes at an opportune moment as Verum Coin prepares for its new listing on XT Exchange, a platform renowned for its extensive user base and a wide array of trading options.

This listing on XT is expected to further propel Verum Coin into the spotlight, providing both traders and investors with new opportunities to engage with this emerging digital asset. The exchange’s robust infrastructure and diverse trading offerings are ideal for supporting Verum Coin’s growth and enhancing its visibility in the competitive cryptocurrency market.

For more details, you can read the full article on the AP website here.

This milestone is a testament to Verum Coin’s advancing presence in the crypto world and its ongoing efforts to be at the forefront of digital currency innovation and adoption.