Technologies
Moderna booster shot and omicron: 2 things we don’t know right now
The omicron variant of virus that causes COVID-19 is spreading across the US. What has Moderna said about the effectiveness of its vaccine and booster against the mutation?
Saying «we underestimate this virus at our peril,» Tedros Adhanom, the director-general of the World Health Organization, said on Tuesday that «omicron is spreading at a rate we have not seen with any previous variant.» To underline the point, a preliminary study out of South Africa on Tuesday suggests that two doses of the Pfizer/BioNTech COVID-19 vaccine may be less effective against the new variant than delta, providing 33% protection.The study by Discovery, a South African health care organization, said the Pfizer vaccine may offer 70% protection against severe complications that result in hospitialization.
Moderna so far has not offered information on how effective its vaccine is against omicron. Moderna Chairman Noubar Afeyan said on Friday the omicron threat is to be taken seriously and his company should know more about the effectiveness of its vaccine this week against the variant.
The early information for US cases of the omicron variant appears to support the concern about weakened protection for those who are fully vaccinated with two doses of the Moderna and Pfizer vaccine or one of Johnson & Johnson. Rochelle P. Walensky, director of the Centers for Disease Control and Prevention, said on Friday that 80% of confirmed US cases with the mutated virus were fully vaccinated for the disease. And a third of the cases had received a booster, although some may have not been boosted in time to be fully protected before being infected with the omicron variant.
Omicron has pushed talk of a COVID booster to top of the page. As of Tuesday, over 24 million in the US have received the Moderna vaccine booster, according to the CDC, which may be key to being protected. «If you want to be optimally protected, you really should get a booster,» Dr. Anthony Fauci,the chief medical adviser to President Joe Biden, said on Sunday.
Scientists are still learning about the omicron variant, including how easily it can pass between people, how serious an infection it can cause and if it can evade immunity. As of Dec. 10, according to Jeff Zients, White House COVID-19 response coordinator, the US is administering 1.1 million booster shots a day, the most since May. The jump comes as the White House is stressing the need for COVID-19 vaccine heading into winter, including booster shots. (President Joe Biden’s campaign also includes «free» at-home COVID-19 test kits and stricter travel rules for international travelers.)
Health professionals believe that booster shots from Moderna and Pfizercould help slow COVID-19’s spread, reducing hospitalization and deaths, asthe effects of the vaccine weaken over time. The CDC urges booster shots for anyone over 18 six months after theirsecond dose of Moderna or Pfizer, or two months after getting asingle Johnson & Johnson dose.
The COVID-19 vaccines have proven so far to be highly effective in preventing hospitalization. People who are unvaccinated are 10 times more likely to be hospitalized if infected. With the federal vaccine mandate halted by a court order, Biden is turning to other measures to get booster shots administered. The government has also ordered 13 million courses of antiviral drugs in anticipation of higher caseloads this winter.
Here’s what you need to know about the Moderna booster, including doses, side effects and how to get a free ride. For more details, here’s the latest on COVID-19 vaccines for kids, how you can get a free COVID-19 test kit soon and what to know about breakthrough infections.
When will Moderna know how effective its COVID vaccine and booster is against the omicron?
The preliminary South Africa study presents an idea for how the Pfizer vaccine works with the omicron variant, it didn’t look at Moderna’s.
Moderna’s Afeyan on Friday told Fox News he expects to his company to have information on the effectiveness of its vaccine against the mutated variant this week. «We don’t have that data yet,» he said. «We are testing thoroughly all aspects of what we could do.»
«Our expectation,» he said, «is that a boosted person will be protected, certainly against serious disease and hospitalization.»
CNET asked Moderna for a comment but didn’t immediately get a response.
Pfizer has been more open about the effectiveness of its vaccine against the variant and said early lab results suggest that the first two doses of its vaccine might not fully protect against the variant and three doses may be needed to restore those protections.
When could we know if a COVID vaccine booster protects against the omicron variant?
A picture «Thethird shot … could not only dramatically increase the level ofprotection,» Fauci said on Sunday, «it very well increase the durabilityof protection.»Fauci said it will take study to study the booster toknow for sure.
Is Moderna making an omicron booster shot?
Scientists worry the omicron variant could spread more quickly than the now-dominant delta variant because of the number of mutations the new strain has compared with delta. Moderna is currently working on an omicron-specific booster vaccine, along with testing a COVID-19 vaccine that could protect against several mutated strains of the coronavirus.
Likeevery other vaccine-maker around the world, Moderna is testing theeffectiveness of its COVID-19 vaccine against omicron, but it may beweeks before lab tests show concrete evidence of how well Modernaprotects people from the new variant.
As part of its boostertesting, Moderna is also investigating whether a 100-microgram dose ofits booster provides better protection against the omicron variant — inother words, a third dose rather than a half dose as the booster iscurrently formulated now.
If Moderna needs to make a new vaccine modified for the variant, it could be available early in2022.
When is it time to get a COVID-19 vaccine booster shot?
If you got Moderna or Pfizer, six months after the date of your second shot listed on yourvaccination card is when you’re eligible to receive your booster dose.The CDC and other health authorities are now urging you to get yourbooster as soon as you’re eligible, to keep your immune response againstomicron, delta and other coronavirus variants as strong as possible.Two months after the Johnson & Johnson vaccine is the time for abooster (more below).
On Dec. 2, Biden also outlined a plan forMedicare to contact the 64 million people it serves and for AARP toreach out to its 38 million senior members. Pharmacies like Walgreens,CVS and RiteAid should also contact people who got a vaccine attheir retail stores when it’s time to schedule another dose.
Should people who are pregnant get a booster shot?
The COVID-19 booster recommendations apply to all people 18 years and older, including those who are pregnant. In fact, the CDC urges pregnant people to get a COVID-19 vaccine — and a booster is half a full vaccine dose.
«People who are pregnant or recently pregnant are more likely to get severely ill with COVID-19 compared with people who are not pregnant,» the CDC says on its website.
A recent study also linked COVID-19 infection in pregnant people to higher risk of stillbirth. However, there is no evidence that getting vaccinated decreases fertility in women or men.
Is the Moderna booster shot a third dose?
Booster shots of COVID-19 vaccines are currently half doses of the same vaccine used in the first two full shots. The goal is to top up the vaccine formula that reinforces the body’s immune response against the virus and its variants. The Moderna booster authorized by the CDC is a 50-microgram dose, while the first two shots were each 100 micrograms.
Moderna is also working on a combination shot that contains this year’s flu vaccine and its COVID-19 booster vaccine, but that’s not available right now.
How do I know which pharmacies have Moderna appointments?
Boosters are available at roughly 80,000 places across the country, including over 40,000 local pharmacies. Some 90% of Americans have a vaccine site within 5 miles of where they live.
A terrific free service in conjunction with the CDC sends you information when you text your ZIP code to this number: 438829. The response will show you COVID-19 vaccine locations in your area, along with the brand they carry for certain age groups, for instance, Moderna 18+. This can save you the trial and error of calling around, or showing up to your appointment to find that your booster of choice isn’t available. The text can also give you a shortcut to make your appointment right from your phone screen.
You can also check Vaccines.gov to see which vaccines are available where, and call 800-232-0233 for vaccine information.
How can I get a free ride to get my booster shot?
Lyft and Uber are offering free rides for some people who need them. An easy way to access those links for more information is through the text feature above You can also go to Lyft.com/vax or call Uber at: 855-921-0033.
Who can get a Moderna booster shot right now?
As of Nov. 19, all US adults — those age 18 and older — are eligible to get a booster shot of the COVID-19 vaccine. They qualify if it’s been at least six months since they’ve received a second dose of either the Moderna or Pfizer vaccine. Those who received the Johnson & Johnson vaccine are eligible for a booster dose after two months. Adults are encouraged to get whatever booster dose is available to them, even if that means mixing and matching vaccine boosters (more below), in other words, getting a different booster shot than their original vaccination.
What are the side effects of Moderna’s booster?
According to the CDC, those who got the Moderna booster dose reported fewer reactions than they did after the second dose of the vaccine. In its study, the CDC found 95% of those who got Moderna for the first round of vaccine shots chose Moderna for the booster dose.
Is it safe to mix and match vaccine and booster brands? Yes
The US Food and Drug Administration has authorized mixing COVID-19 boosters, which in the US means Moderna, Pfizer and Johnson & Johnson. Any adult eligible for a booster can get any of the available brands of coronavirus vaccines. If you initially received Johnson & Johnson and it’s been two months or longer since you received the initial dose, you’ll be able to get the Moderna or Pfizer booster. If you received Moderna or Pfizer for your first two shots, you could pick any authorized vaccine available to you — including J&J — if you qualify and it’s been six months or longer since your second shot.
Is the Moderna COVID-19 booster shot still free?
All booster shots will be free, regardless of immigration or health insurance status. However, depending on where you get your booster shot — for example, at a local pharmacy — you may be asked to log your insurance status. You may be asked to provide your insurance card information, including your name, date of birth and membership number. You will not be charged for your COVID-19 vaccine or booster shot.
Will I need another COVID-19 booster shot?
The CDC updated its guidance to say that in 2022, some immunocompromised people will be able to get a fourth COVID-19 booster shot. It’s unclear if other groups will need to get a fourth dose at this time, but guidance could change in light of the omicron variant.
For more on coronavirus treatments and vaccines, here’s what we know about monoclonal antibody treatments, the new federal vaccine mandates and why some people may not want the shot.
What does the Moderna booster shot do?
A COVID-19 booster shot — whether from Moderna, Pfizer or Johnson & Johnson — tops off your immune response and guards against a breakthrough COVID-19 infection as the vaccine’s effectiveness decreases over time.
Recent studies of the Pfizer and AstraZeneca vaccines show that their effectiveness can begin to wane after six months. Moderna said early data suggests that those who received the Moderna vaccine in 2020 are showing a higher rate of breakthrough COVID-19 infections than those vaccinated this year, suggesting the need for a booster to maintain high levels of protection.
The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.
Technologies
Apple Reportedly Planning Cheaper Macs to Compete With Budget Chromebooks, PCs
Apple doesn’t market its machines as affordable, but that could be changing.
Apple may release more affordable Mac laptops to compete with Chromebooks and budget-friendly Windows laptops as early as 2026.
Bloomberg’s Mark Gurman reports the company has plans to roll out a machine for «well under $1,000.» According to Gurman, the new laptop is already in early production under the codename J700. This matches earlier rumors that a low-cost MacBook Air was in the pipeline at around $599, which would allow Apple to directly compete with other cheap laptops, including Chromebooks and Windows PCs.
A representative for Apple did not immediately respond to a request for comment.
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According to the report, costs will be kept down by using a lower-end LCD that’s smaller than the 13.6-inch MacBook Air, potentially making the new affordable MacBook as small as 12 inches.
Another way Apple could reduce the cost is by using an A-series iPhone chip, which falls short of the top-tier performance offered by the MacBook Pro or the current M4 Air. The upcoming chip may be a variant of the A19 Pro chip that debuted with the iPhone 17 Pro and iPhone Air, which Apple says is capable of MacBook-level performance.
As CNET senior editor Matt Elliott noted, the promise is a bold one. He speculates that the rumored $599 MacBook Air may get the same smartphone processor, or an M-series chip based on that architecture.
Bloomberg also reports that a MacBook Pro with an M5 Pro and M5 Max chip is in development, and Apple has completed work on a MacBook Air powered by the M5 chip, which is planned for release early next year.
The affordable laptop would be designed for casual users, students and businesses, specifically individuals who need a device for tasks such as web browsing, light media editing and document creation. The tech giant is also targeting the education market, as well as iPad buyers who may also want a traditional laptop.
«If this is strictly a move to entice consumers with a high-quality, lower-cost MacBook running MacOS in place of an iPad with a keyboard, then yes, Apple can likely take a chunk of that market,» said Josh Goldman, managing editor at CNET.
«Making inroads into the education market at this point, where Chromebooks have taken over since the pandemic, will prove challenging, though I’m sure it’s nothing that throwing billions of dollars at can’t fix,» CNET’s Goldman said.
This price range is ‘a big departure’
Price is likely to be key here. A $599 price tag would place the new Mac in the same range as more affordable Chromebooks and entry-level laptops, representing a significant change from Apple’s previous strategy.
«Apple potentially dipping into the Chromebook range of $300 to $500 with a new MacBook is a big departure,» said Goldman.
He notes that one of Apple’s most affordable MacBooks is the M4 MacBook Air, available new starting at $999 for the 13-inch model. Walmart still sells a new M1 MacBook Air, a 5-year-old laptop, for around $600.
By contrast, an iPad 11th Gen with a Magic Keyboard will run you around $600, making it clear that Apple’s target market for the rumored device is students and lighter users.
Apple typically hasn’t targeted the lower-priced segment of the market with its MacBooks. However, with consumer wallets under pressure from inflation, high tariffs and layoffs, an affordable MacBook could be imperative and timely.
Technologies
Today’s NYT Connections: Sports Edition Hints and Answers for Nov. 5, #408
Here are hints and the answers for the NYT Connections: Sports Edition puzzle for Nov. 5, No. 408.
Looking for the most recent regular Connections answers? Click here for today’s Connections hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle and Strands puzzles.
Today’s Connections: Sports Edition is pretty diverse. The blue answers stuck out to me right away, because some of them are super famous and the others felt like they belonged with those names. If you’re struggling but still want to solve it, read on for hints and the answers.
Connections: Sports Edition is published by The Athletic, the subscription-based sports journalism site owned by the Times. It doesn’t show up in the NYT Games app but appears in The Athletic’s own app. Or you can play it free online.
Read more: NYT Connections: Sports Edition Puzzle Comes Out of Beta
Hints for today’s Connections: Sports Edition groups
Here are four hints for the groupings in today’s Connections: Sports Edition puzzle, ranked from the easiest yellow group to the tough (and sometimes bizarre) purple group.
Yellow group hint: How to see a game.
Green group hint: Soccer.
Blue group hint: Giddy up!
Purple group hint: Not a run play.
Answers for today’s Connections: Sports Edition groups
Yellow group: Ways to consume a sporting event.
Green group: NWSL teams.
Blue group: Triple Crown horse racing winners.
Purple group: Pass ____.
Read more: Wordle Cheat Sheet: Here Are the Most Popular Letters Used in English Words
What are today’s Connections: Sports Edition answers?
The yellow words in today’s Connections
The theme is ways to consume a sporting event. The four answers are in person, radio, streaming and television.
The green words in today’s Connections
The theme is NWSL teams. The four answers are Current, Dash, Pride and Spirit.
The blue words in today’s Connections
The theme is Triple Crown horse racing winners. The four answers are Citation, Gallant Fox, Omaha and Secretariat.
The purple words in today’s Connections
The theme is pass ____. The four answers are breakup, interference, protection and rush.
Technologies
Today’s NYT Connections Hints, Answers and Help for Nov. 5, #878
Here are some hints and the answers for the NYT Connections puzzle for Nov. 5, #878.
Looking for the most recent Connections answers? Click here for today’s Connections hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle, Connections: Sports Edition and Strands puzzles.
Today’s NYT Connections puzzle has a diverse mix of topics, including a neat blue category that music fans will ace. And it isn’t too tough, but if you need help, you’re in the right place. Read on for clues and today’s Connections answers.
The Times now has a Connections Bot, like the one for Wordle. Go there after you play to receive a numeric score and to have the program analyze your answers. Players who are registered with the Times Games section can now nerd out by following their progress, including the number of puzzles completed, win rate, number of times they nabbed a perfect score and their win streak.
Read more: Hints, Tips and Strategies to Help You Win at NYT Connections Every Time
Hints for today’s Connections groups
Here are four hints for the groupings in today’s Connections puzzle, ranked from the easiest yellow group to the tough (and sometimes bizarre) purple group.
Yellow group hint: Mess up.
Green group hint: Lead pipe is another one.
Blue group hint: They command the stage.
Purple group hint: Not snow, but …
Answers for today’s Connections groups
Yellow group: Make a hash of.
Green group: Weapons in the game Clue.
Blue group: Iconic soul singers.
Purple group: Rain ____.
Read more: Wordle Cheat Sheet: Here Are the Most Popular Letters Used in English Words
What are today’s Connections answers?
The yellow words in today’s Connections
The theme is make a hash of. The four answers are blow, botch, butcher and spoil.
The green words in today’s Connections
The theme is weapons in the game Clue.The four answers are candlestick, knife, rope and wrench.
The blue words in today’s Connections
The theme is iconic soul singers. The four answers are (Anita) Baker, (Roberta) Flack, (Aretha) Franklin and (Gladys) Knight.
The purple words in today’s Connections
The theme is rain ____. The four answers are bow, coat, forest and maker.
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