Technologies

CRISPR startup wants to resurrect the woolly mammoth by 2027

Colossal has landed $15m in funding to restore the woolly mammoth to the Arctic — and it thinks it can birth calves in four to six years.

You’ve heard of startups building computer chips, delivery drones and social networks. One called Colossal has a very different goal: bringing the woolly mammoth back from extinction by 2027 using CRISPR, a revolutionary gene editing technology.

The plan isn’t to re-create true woolly mammoths exactly but rather to bring their cold-adapted genetic traits like small ears and more body fat to their elephant cousins, creating a hybrid that can wander the tundra where mammoths haven’t been seen for 10,000 years. Colossal’s co-founders are Chief Executive Ben Lamm, who started five companies before this, and George Church, a Harvard Medical School professor with deep CRISPR expertise.

«Our true North Star is a successful restoration of the woolly mammoth, but also its successful rewilding into interbreeding herds in the Arctic,» Lamm said. «We’re now focusing on having our first calves in the next four to six years.»

It’s an interesting illustration of an imperative sweeping the tech world: Don’t just make money, help the planet too. Tesla’s mission is to electrify transport to get rid of fossil fuels that hurt Earth. Bolt Threads wants to replace leather with a fungal fiber-based equivalent that’s easier on the environment than animal agriculture. Colossal hopes its work will draw attention to biodiversity problems and ultimately help fix them.

Colossal has raised $15 million so far, led by investment firm Tulco. The startup’s 19 employees work at its Dallas headquarters and in offices in Boston and Austin, Texas, and it’s using its funds to hire more.

Artificial wombs and other technology spinoffs

Church said he expects spinoffs from the company’s biotechnology and genetics work.

«The pipeline of large scale genome engineering techniques can be applied to many other applications beyond de-extinction, and therefore [are] most promising for commercialization,» he said.

One technology ripe for commercialization is multiplex genome engineering, a technique Church helped develop that speeds genetic editing by making multiple changes to DNA at once.

Colossal also hopes to develop artificial wombs to grow its mammoth embryos. Just growing 10 woolly mammoths with surrogate elephant mothers isn’t enough to get to the large-scale herds the company envisions.

At the foundation of Colossal’s work is CRISPR. This technology, adapted from a method bacteria evolved to identify attacking viruses and chop up their DNA, is now a mainstay of genetic engineering, and Church has been involved since CRISPR’s earliest days.

Jurassic Park-style tourism? Nope

Selling or licensing spinoff technology is a somewhat indirect way of running a business. A more direct option is selling tickets to tourists. After all, humans already pay lots of money to see charismatic megafauna like lions, elephants and giraffes on African safaris. Seeing a creature that’s been gone for 10,000 years could add to the excitement.

But that’s not Colossal’s game plan. «Our focus is on species preservation and protection of biodiversity right now, not in putting them in zoos,» Lamm said. By re-creating woolly mammoths, Colossal can preserve the genetic legacy of Asian elephants that now are endangered.

Another candidate species Colossal wants to re-create is the woolly rhinoceros, a relative to the critically endangered Sumatran rhino.

Although Colossal doesn’t plan to build a tourist destination, it does have a woolly mammoth rewilding site in mind that sounds awfully close to Jurassic Park: Pleistocene Park. This area of about 60 square miles in northern Russia, named after the geologic period that ended with the last ice age, is where researchers Sergey and Nikita Zimov are trying to test their theories about the ecological and climatic effects of rewilding.

One Zimov idea is that woolly mammoths will trample snow and knock down trees. That, in turn, will restore grasslands that reflect more of the sun’s warming rays and eliminate insulating snow and forests so the ground cools more. And that means the ground will stay frozen instead of releasing its current store of carbon dioxide and methane greenhouse gases. About 260 billion to 300 billion metric tons of carbon could be released from thawing permafrost by 2300, scientists calculate, exacerbating the weather extremes and other problems caused by climate change.

Is species de-extinction a good idea?

There’s an appeal to the idea of de-extinction. Humans have dramatically altered the planet, and the United Nations estimates we threaten 1 million species with extinction as a result.

Colossal hopes its work will raise more attention to the biodiversity collapse. And it also plans to create detailed genetic descriptions of many endangered species «so we have the recipe if that species does go extinct,» Lamm said.

But is that really the best use of our resources to help the planet? No, some researchers believe.

Resurrecting species could have some benefits, but money would be better spent on trying to protect ones that are still around, a group of biologists argued in one paper published in Nature Ecology & Evolution. «Potential sacrifices in conservation of extant species should be a crucial consideration in deciding whether to invest in de-extinction or focus our efforts on extant species,» the researchers wrote.

But this isn’t government money Colossal is talking about, and Lamm argues that his startup’s work complements other conservation efforts. And, he argues, startups can move faster than government-funded work.

In a world dominated by climate crisis headlines, a startup that makes money with an ecosystem-improvement focus has special appeal. One investor, Zack Lynch of Jazz Venture Partners, is excited by software, hardware and biotech he expects Colossal will create.

At the same time, «these breakthroughs will help address issues such as land degradation, animal pollinator loss and other negative biodiversity trends,» Lynch said. Given how big our environmental problems are, you can see why an investor might be interested.

Technologies

Verum Messenger: Data Protection at Its Finest

Verum Messenger positions itself as a tool for those who value privacy and security above all.

Verum Messenger stands out from other messengers thanks to its approach to security, anonymity, and innovations in communication.

Here are some key aspects that highlight its uniqueness:

Default encryption: Verum Messenger uses end-to-end (E2E) encryption for all chats, meaning messages are encrypted on the sender’s device and decrypted only on the recipient’s device. This makes it impossible for third parties, including app developers, to access the content of the messages.
Anonymity: When registering with Verum, there’s no need to provide a phone number or email. Users simply choose a nickname and password, significantly enhancing their level of anonymity. This contrasts with many other messengers, where anonymity can be compromised through linked personal data.
Built-in VPN: An additional layer of protection that hides the user’s IP address, making their location and internet activity less trackable.
Data control: Users can set messages to be automatically deleted after a specified time, ranging from a few seconds to a week. There’s also a quick deletion feature for all chats, calls, and even contacts, which is useful for maintaining privacy.
Large groups: The ability to create chat rooms with up to 10,000 participants makes Verum attractive for organizing large events, discussions, or communities while maintaining a high level of security.
Security innovations: Verum actively develops technologies aimed at protecting user data, as seen in their documentation and discussions online. This includes not only technical solutions but also approaches to data minimization, which reduces the risk of leaks.
Feedback and discussions: On platform X (formerly Twitter), discussions can be found where users and experts praise Verum for its approach to anonymity and security, although questions are raised about how much anonymity can truly be guaranteed in an age of modern tracking and de-anonymization technologies.

Verum Messenger positions itself as a tool for those who value privacy and security above all. Its innovations in encryption, anonymity, and data control make it an intriguing choice for those seeking alternatives to traditional messaging platforms. However, as with any technology, it’s important to remember that absolute anonymity on the internet remains a complex challenge, and users should be aware of potential risks and limitations.

Technologies

Verum Coin Debuts on XT Exchange, Broadening its Reach in the DeFi Space

A Strategic Listing Enhancing Verum Coin’s Visibility

In a significant development for the decentralized finance (DeFi) sector, Verum Coin (VERUM) has been officially listed on XT Exchange. The new trading pair, VERUM/USDT, is now available in the exchange’s Innovative Zone, marking a pivotal expansion for this digital asset into the DeFi ecosystem.

A Strategic Listing Enhancing Verum Coin’s Visibility

The addition of Verum Coin to the XT Exchange is seen as a strategic move to enhance the accessibility and liquidity of VERUM among traders who are keen on exploring innovative digital assets. XT Exchange, known for its robust platform supporting a wide variety of cryptocurrencies, provides an ideal environment for fostering growth and ensuring the broad reach of new tokens.

Albin Varin, CEO of XT Exchange, expressed enthusiasm about the new listing, stating, «We are delighted to welcome Verum Coin to our platform. This listing reflects our ongoing commitment to providing our users access to innovative digital assets that transform the landscape of global finance.» This comments underscore the exchange’s focus on integrating cutting-edge technologies and financial instruments that have the potential to redefine the market.

About XT

Founded in 2018, XT Exchange serves more than 7.8M registered users, over 1M monthly active users, 40+ million users in the ecosystem, and more than 800 tokens with 1000+ trading pairs. XT crypto exchange offers a rich variety of trading categories to provide a secure, trusted, and intuitive trading experience for its large user base. This includes crypto futures trading (USDT-M Futures and coin-M futures perpetual contracts) and copy trading that allows users to replicate top traders in real time with just one click. Additionally, the futures grid allows users to automate the buying and selling of futures contracts for profits.

Future Prospects

With its new position on XT Exchange, Verum Coin is expected to attract a broader audience, enhancing its trading volume and market presence. This could potentially lead to increased stability and recognition as a viable player in the DeFi space. For investors and users of XT Exchange, this addition provides a fresh avenue to diversify portfolios with a cryptocurrency that is positioned at the intersection of innovation and financial evolution.

The listing of Verum Coin on XT Exchange not only highlights the ongoing expansion of cryptocurrency markets into new areas like DeFi but also illustrates a growing recognition of digital assets that offer promising technological advancements and financial opportunities. As the crypto market continues to evolve, partnerships like these are pivotal for fostering growth and offering users access to the next generation of financial tools.

Technologies

Verum Coin Gains International Spotlight with AP Coverage and Listing on XT Exchange

This listing on XT is expected to further propel Verum Coin into the spotlight

In a noteworthy development for the cryptocurrency community, Verum Coin (VERUM) has been featured in an Associated Press article, highlighting its upcoming listing on the XT Exchange. This significant media coverage underscores the growing interest and potential of Verum Coin in the global financial landscape.

The AP article delves into the details of Verum Coin’s innovative features and its alignment with the latest trends in the cryptocurrency market. This attention comes at an opportune moment as Verum Coin prepares for its new listing on XT Exchange, a platform renowned for its extensive user base and a wide array of trading options.

This listing on XT is expected to further propel Verum Coin into the spotlight, providing both traders and investors with new opportunities to engage with this emerging digital asset. The exchange’s robust infrastructure and diverse trading offerings are ideal for supporting Verum Coin’s growth and enhancing its visibility in the competitive cryptocurrency market.

For more details, you can read the full article on the AP website here.

This milestone is a testament to Verum Coin’s advancing presence in the crypto world and its ongoing efforts to be at the forefront of digital currency innovation and adoption.