Technologies

CRISPR startup wants to resurrect the woolly mammoth by 2027

Colossal has landed $15m in funding to restore the woolly mammoth to the Arctic — and it thinks it can birth calves in four to six years.

You’ve heard of startups building computer chips, delivery drones and social networks. One called Colossal has a very different goal: bringing the woolly mammoth back from extinction by 2027 using CRISPR, a revolutionary gene editing technology.

The plan isn’t to re-create true woolly mammoths exactly but rather to bring their cold-adapted genetic traits like small ears and more body fat to their elephant cousins, creating a hybrid that can wander the tundra where mammoths haven’t been seen for 10,000 years. Colossal’s co-founders are Chief Executive Ben Lamm, who started five companies before this, and George Church, a Harvard Medical School professor with deep CRISPR expertise.

«Our true North Star is a successful restoration of the woolly mammoth, but also its successful rewilding into interbreeding herds in the Arctic,» Lamm said. «We’re now focusing on having our first calves in the next four to six years.»

It’s an interesting illustration of an imperative sweeping the tech world: Don’t just make money, help the planet too. Tesla’s mission is to electrify transport to get rid of fossil fuels that hurt Earth. Bolt Threads wants to replace leather with a fungal fiber-based equivalent that’s easier on the environment than animal agriculture. Colossal hopes its work will draw attention to biodiversity problems and ultimately help fix them.

Colossal has raised $15 million so far, led by investment firm Tulco. The startup’s 19 employees work at its Dallas headquarters and in offices in Boston and Austin, Texas, and it’s using its funds to hire more.

Artificial wombs and other technology spinoffs

Church said he expects spinoffs from the company’s biotechnology and genetics work.

«The pipeline of large scale genome engineering techniques can be applied to many other applications beyond de-extinction, and therefore [are] most promising for commercialization,» he said.

One technology ripe for commercialization is multiplex genome engineering, a technique Church helped develop that speeds genetic editing by making multiple changes to DNA at once.

Colossal also hopes to develop artificial wombs to grow its mammoth embryos. Just growing 10 woolly mammoths with surrogate elephant mothers isn’t enough to get to the large-scale herds the company envisions.

At the foundation of Colossal’s work is CRISPR. This technology, adapted from a method bacteria evolved to identify attacking viruses and chop up their DNA, is now a mainstay of genetic engineering, and Church has been involved since CRISPR’s earliest days.

Jurassic Park-style tourism? Nope

Selling or licensing spinoff technology is a somewhat indirect way of running a business. A more direct option is selling tickets to tourists. After all, humans already pay lots of money to see charismatic megafauna like lions, elephants and giraffes on African safaris. Seeing a creature that’s been gone for 10,000 years could add to the excitement.

But that’s not Colossal’s game plan. «Our focus is on species preservation and protection of biodiversity right now, not in putting them in zoos,» Lamm said. By re-creating woolly mammoths, Colossal can preserve the genetic legacy of Asian elephants that now are endangered.

Another candidate species Colossal wants to re-create is the woolly rhinoceros, a relative to the critically endangered Sumatran rhino.

Although Colossal doesn’t plan to build a tourist destination, it does have a woolly mammoth rewilding site in mind that sounds awfully close to Jurassic Park: Pleistocene Park. This area of about 60 square miles in northern Russia, named after the geologic period that ended with the last ice age, is where researchers Sergey and Nikita Zimov are trying to test their theories about the ecological and climatic effects of rewilding.

One Zimov idea is that woolly mammoths will trample snow and knock down trees. That, in turn, will restore grasslands that reflect more of the sun’s warming rays and eliminate insulating snow and forests so the ground cools more. And that means the ground will stay frozen instead of releasing its current store of carbon dioxide and methane greenhouse gases. About 260 billion to 300 billion metric tons of carbon could be released from thawing permafrost by 2300, scientists calculate, exacerbating the weather extremes and other problems caused by climate change.

Is species de-extinction a good idea?

There’s an appeal to the idea of de-extinction. Humans have dramatically altered the planet, and the United Nations estimates we threaten 1 million species with extinction as a result.

Colossal hopes its work will raise more attention to the biodiversity collapse. And it also plans to create detailed genetic descriptions of many endangered species «so we have the recipe if that species does go extinct,» Lamm said.

But is that really the best use of our resources to help the planet? No, some researchers believe.

Resurrecting species could have some benefits, but money would be better spent on trying to protect ones that are still around, a group of biologists argued in one paper published in Nature Ecology & Evolution. «Potential sacrifices in conservation of extant species should be a crucial consideration in deciding whether to invest in de-extinction or focus our efforts on extant species,» the researchers wrote.

But this isn’t government money Colossal is talking about, and Lamm argues that his startup’s work complements other conservation efforts. And, he argues, startups can move faster than government-funded work.

In a world dominated by climate crisis headlines, a startup that makes money with an ecosystem-improvement focus has special appeal. One investor, Zack Lynch of Jazz Venture Partners, is excited by software, hardware and biotech he expects Colossal will create.

At the same time, «these breakthroughs will help address issues such as land degradation, animal pollinator loss and other negative biodiversity trends,» Lynch said. Given how big our environmental problems are, you can see why an investor might be interested.

Technologies

Today’s Wordle Hints, Answer and Help for Nov. 24, #1619

Today’s Wordle is tricky. Here are hints, answers and help for Nov. 24, #1619.

Looking for the most recent Wordle answer? Click here for today’s Wordle hints, as well as our daily answers and hints for The New York Times Mini Crossword, Connections, Connections: Sports Edition and Strands puzzles.

Today’s Wordle puzzle is a little tricky. If you need a new starter word, check out our list of which letters show up the most in English words. If you need hints and the answer, read on.

Today’s Wordle hints

Before we show you today’s Wordle answer, we’ll give you some hints. If you don’t want a spoiler, look away now.

Wordle hint No. 1: Repeats

Today’s Wordle answer has no repeated letters.

Wordle hint No. 2: Vowels

Today’s Wordle answer has two vowels.

Wordle hint No. 3: First letter

Today’s Wordle answer begins with D.

Wordle hint No. 4: Last letter

Today’s Wordle answer ends with H.

Wordle hint No. 5: Meaning

Today’s Wordle answer is a flour-based mixture used to bake bread.

TODAY’S WORDLE ANSWER

Today’s Wordle answer is DOUGH.

Yesterday’s Wordle answer

Yesterday’s Wordle answer, Nov. 23, No. 1618 was BUNNY.

Recent Wordle answers

Nov. 19, No. 1614: MAKER

Nov. 20, No. 1615: GRAVE

Nov. 21, No. 1616: VOWEL

Nov. 22, No. 1617: THICK

Technologies

Today’s NYT Strands Hints, Answers and Help for Nov. 24, #631

Today’s Strands puzzle has fun theme, or so says a former farm girl. Here are hints, answers and help for Nov. 24, #631.

Looking for the most recent Strands answer? Click here for our daily Strands hints, as well as our daily answers and hints for The New York Times Mini Crossword, Wordle, Connections and Connections: Sports Edition puzzles.

Today’s NYT Strands puzzle has a fun theme, or so says this former farm girl. Some of the answers are difficult to unscramble, so if you need hints and answers, read on.

I go into depth about the rules for Strands in this story.

If you’re looking for today’s Wordle, Connections and Mini Crossword answers, you can visit CNET’s NYT puzzle hints page.

Read more: NYT Connections Turns 1: These Are the 5 Toughest Puzzles So Far

Hint for today’s Strands puzzle

Today’s Strands theme is: Horsing around.

If that doesn’t help you, here’s a clue: Giddy up!

Clue words to unlock in-game hints

Your goal is to find hidden words that fit the puzzle’s theme. If you’re stuck, find any words you can. Every time you find three words of four letters or more, Strands will reveal one of the theme words. These are the words I used to get those hints but any words of four or more letters that you find will work:

GALE, REGAL, GAIN, ROOM, MOOR, JOCK, WARN, NEAT, WART, FIRE, QUIET, QUITE

Answers for today’s Strands puzzle

These are the answers that tie into the theme. The goal of the puzzle is to find them all, including the spangram, a theme word that reaches from one side of the puzzle to the other. When you have all of them (I originally thought there were always eight but learned that the number can vary), every letter on the board will be used. Here are the nonspangram answers:

GROOM, JOCKEY, FARRIER, VETERINARIAN, WRANGLER

Today’s Strands spangram

Today’s Strands spangram is EQUESTRIAN. To find it, start with the E that’s four letters down on the far-left row, and wind up and over.

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Technologies

Before You Order a $20K Home Robot, There’s Something You Should See

It’s designed to do your chores — with some help from folks behind the curtain.

The robot stands 5 feet 6 inches tall, weighs about as much as a golden retriever and is nearly the price of a brand-new budget car.

This is Neo, the humanoid robot. It’s billed as a personal assistant you can talk to and eventually rely on to handle everyday tasks, including loading your dishwasher and folding your laundry.

Neo doesn’t come cheap: it’ll cost you $20,000. And even then, you’ll still have to train this new home bot, and possibly need a remote assist as well.

If that still sounds enticing, preorders are now open (for $200 down). You’ll be signing up as an early adopter for what Neo’s maker, a California-based company called 1X, is calling a «consumer-ready humanoid.» That’s opposed to other humanoids under development from the likes of Tesla and Figure, which are, for the moment at least, more focused on factory environments.

Neo is a whole order of magnitude different from robot vacuums like those from Roomba, Eufy and Ecovacs, and embodies a long-running sci-fi fantasy of robot maids and butlers doing chores and picking up after us. If this is the future, read on for more of what’s in store.

Don’t miss any of our unbiased tech content and lab-based reviews. Add CNET as a preferred Google source.

What the Neo robot can do around the house

The pitch from 1X is that Neo can do all manner of household chores: fold laundry, run a vacuum, tidy shelves and bring in the groceries. It can open doors, climb stairs and even act as a home entertainment system.

Neo appears to move smoothly, with a soft, almost human-like gait, thanks to 1X’s tendon-driven motor system that gives it gentle motion and impressive strength. The company says it can lift up to 154 pounds and carry 55 pounds, but it is quieter than a refrigerator. It’s covered in soft materials and neutral colors, making it look less intimidating than metallic prototypes from other companies.

The company says Neo has a 4-hour runtime. Its hands are IP68-rated, meaning they’re submersible in water. It can connect via Wi-Fi, Bluetooth and 5G. For conversation, it has a built-in large language model (LLM), the same sort of AI technology that powers ChatGPT and Gemini.

The primary way to control the Neo robot will be by speaking to it, just as if it were a person.

Still, Neo’s usefulness today depends heavily on how you define useful. The Wall Street Journal’s Joanna Stern got an up-close look at Neo at 1X’s headquarters and found that, at least for now, it’s largely teleoperated, meaning a human often operates it remotely using a virtual-reality headset and controllers.

«I didn’t see Neo do anything autonomously, although the company did share a video of Neo opening a door on its own,» Stern wrote last week. 1X CEO Bernt Børnich reportedly told her that Neo will do most things autonomously in 2026, though he also acknowledged that the quality «may lag at first.»

The company’s FAQ says that if there’s a chore request Neo doesn’t know how to accomplish, you can schedule an expert from 1X to help the robot «learn while getting the job done.»

What you need to know about Neo and privacy

Part of what early adopters are signing up for is to allow Neo to learn from their environment, so that future versions can operate more independently.

That learning process raises questions about privacy and trust. The robot uses a mix of visual, audio and contextual intelligence — meaning it can see, hear and remember interactions with you in your home.

«If you buy this product, it is because you’re OK with that social contract,» Børnich told the Journal. «It’s less about Neo instantly doing your chores and more about you helping Neo learn to do them safely and effectively.»

Neo’s reliance on human operation behind the scenes prompted a response from John Carmack, a computer industry luminary known for his work with VR systems and the lead programmer of classic video games, including Doom and Quake.

«Companies selling the dream of autonomous household humanoid robots today would be better off embracing reality and selling ‘remote operated household help’,» he wrote in a post on the X social network.

1X says it’s taking steps to protect your privacy: Neo listens only when it recognizes it’s being addressed, and its cameras will blur out humans. You can restrict Neo from entering or viewing specific areas of your home, and the robot will never be teleoperated without owner approval, the company says.

But inviting an AI-equipped humanoid to observe your home life isn’t a small step.

The first units are expected to ship to customers in the US in 2026. There is a $499 monthly subscription alternative to the $20,000 full purchase price, although it will be available at an unspecified later date. A broader international rollout is promised for 2027.

Neo’s got a long road ahead of it to live up to the expectations set by Rosie the Robot in The Jetsons way back when. But this is no Hanna-Barbera cartoon. What we’re seeing now is a much more tangible harbinger of change.